JAMA Author Interviews: Recent Episodes
JAMA Network
Interviews with leading researchers and thinkers in health care about practice-changing research, innovations, and the most pressing issues facing medicine and health care today from JAMA, the Journal of the American Medical Association.
The United States has witnessed a staggering rise in obesity beginning in the early 1980s, leading to a wide array of important health consequences including heart disease, diabetes, and premature death. In this episode of Healthy Dialogue, Host Derek C. Angus, MD, MPH, talks with Marion Nestle, PhD, MPH, Paulette Goddard Professor Emerita at New York University and influential author on food politics, for a candid conversation about how society became ensnared in the current obesity epidemic and what might untangle it. Related Content:
- Food Politics, Obesity, and the "Wicked Mess" We Are In
This episode of Healthy Dialogue explores the history and future of science funding in the US in light of recent changes, and proposed changes, from the federal government. Host Derek Angus, MD, MPH, speaks with former editor in chief of Science and a former director of the National Institute of General Medical Sciences at the NIH, Jeremy Berg, PhD. Related Content:
- Why and How Should the Government Fund Biomedical Research?
In this episode of Healthy Dialogue, host Derek Angus, MD, MPH sits down with Dimitri Christakis, MD, MPH, to discuss whether social media use disorder is a real phenomenon, the mechanisms behind it, and its consequences for young people. Related Content:
- Social Media Use by Children—Wonderful, Hazardous, or Something in Between?
A growing number of young adults are being diagnosed with cancer, particularly colorectal cancer, but the underlying cause remains unclear. In this episode of Healthy Dialogue, Kimmie Ng, MD, MPH, and Ilana Richman, MD, MHS, discuss the increase in cases, potential causes, diagnostics, treatment, and more. Related Content:
- Unpacking the Rise in Early-Onset Cancer
Private equity investment continues to expand across US health care. Current estimates put private equity ownership at almost 10% of hospitals and more than one-fifth of for-profit hospitals nationwide. In this episode of Healthy Dialogue, Sneha Kannan, MD, MS, assistant professor of critical care medicine at the University of Pittsburgh, joins host Derek C. Angus, MD, MPH, to discuss the complex role of private equity in health care and what it means for clinicians and patients. Related Content:
- Private Equity's Growing Presence in Health Care—Promise or Peril?
Dementia affects millions of people globally, causing profound memory loss and cognitive impairment and compromising the ability to function independently in day-to-day life. In this episode of Healthy Dialogue, host Derek C. Angus, MD, MPH, sat down with Gil Rabinovici, MD, a neurologist and director of the UCSF Alzheimer's Disease Research Center, to discuss the latest developments in dementia and Alzheimer disease research. Related Content:
- A New Era in Dementia—Advances in Diagnostic Blood Tests, Novel Drugs, and the Power of Lifestyle Changes
The rise in use and function of ambient AI scribes is arguably one of the fastest technologic changes ever seen in health care. In this episode of Healthy Dialogue, host Derek Angus, MD, MPH, is joined by Vincent Liu, MD, MS, Chief Data Officer of The Permanente Medical Group in Kaiser Permanente, to discuss the rapidly changing world of ambient AI. Related Content:
- Ambient AI Scribes and the Quintuple Aim
- Changes in Clinician Time Expenditure and Visit Quantity With Adoption of Artificial Intelligence–Powered Scribes
- AI Scribes Are Here, but Is Health Care Ready?
What is behind the rise in autism diagnoses? Join Jeremy Veenstra-VanderWeele, MD, professor of developmental neuropsychiatry at Columbia University, and JAMA Psychiatry Editor Dost Öngür, MD, PhD, as they discuss the history of autism spectrum disorder, the role that genetics and environmental factors play, the importance of early intervention in treatment, and more with JAMA Senior Editor Derek Angus, MD, MPH. Related Content:
- Autism—Understanding Diagnosis, Prevalence, and Treatment
Go beyond the latest discoveries with nuanced, in-depth conversations in Healthy Dialogue, a podcast from the JAMA Network. Host and JAMA Senior Editor, Derek C. Angus, MD, MPH, sits down with the world's leading experts to explore the most pressing issues in health and health care.
In this episode, JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, and Medical News Director Jennifer Abbasi discuss the journal's inaugural Research of the Year roundup. Related Content:
- Research of the Year 2025
SOFA-2, validated in more than 3 million intensive care unit (ICU) patients, incorporates contemporary organ support treatments, showing strong predictive validity for ICU mortality in diverse international settings. Coauthor Mervyn Singer, MD, joins JAMA Associate Editor Christopher W. Seymour, MD, MSc, to discuss. Related Content:
- Rationale and Methodological Approach Underlying the Development of the Sequential Organ Failure Assessment (SOFA)–2 Score
- Development and Validation of the Sequential Organ Failure Assessment (SOFA)-2 Score
- A Revision to Organ Failure Assessment in Critically Ill Patients
Epidemiologist Brian Lee, PhD, discusses his study on acetaminophen use during pregnancy and children's risk of autism and other neurodevelopmental disorders in this interview with JAMA Deputy Editor Linda Brubaker, MD. Related Content:
- Acetaminophen Use in Pregnancy—Study Author Explains the Data
Delaying diagnosis of parkinsonism can mean delaying care. In a study recently published in JAMA Neurology, David Vaillancourt, PhD, and colleagues tested the ability of an AI model to differentiate between Parkinson disease and other neurodegenerative disorders when paired with MRI. He joins JAMA and JAMA+ AI Associate Editor Yulin Hswen, ScD, MPH to discuss. Related Content:
- A Large Proportion of Parkinson Disease Diagnoses Are Wrong—Here's How AI Could Help
- Automated Imaging Differentiation for Parkinsonism
Dalbavancin, a long-acting IV lipoglycopeptide, may be an option for the treatment of complicated Staphylococcus aureus bacteremia without requiring long-term IV access. Author Thomas L. Holland, MD, MSc, from Duke University School of Medicine discusses key points of the DOTS randomized clinical trial and more with JAMA Deputy Editor Preeti Malani, MD, MSJ. Related Content:
- Dalbavancin for Treatment of Staphylococcus aureus Bacteremia
- Management of Staphylococcus aureus Bacteremia
Interview with Sameer Jauhar, PhD, author of Incidence and Nature of Antidepressant Discontinuation Symptoms: A Systematic Review and Meta-Analysis. Hosted by John Torous, MD. Related Content:
- Incidence and Nature of Antidepressant Discontinuation Symptoms
Interview with Dennis J. Rivet II, MD, author of GLP-1 Receptor Agonists in Idiopathic Intracranial Hypertension. Hosted by Cynthia E. Armand, MD. Related Content:
- GLP-1 Receptor Agonists in Idiopathic Intracranial Hypertension
Nationwide data are unavailable regarding changes in intensive care unit (ICU) outcomes over the past 10 years, limiting understanding of practice changes. Authors Emily Moin, MD, MBE, and Scott D. Halpern, MD, PhD, MBE, of the University of Pennsylvania join JAMA Associate Editor Christopher W. Seymour, MD, MSc, to discuss how ICU care and outcomes have changed in the US over the past decade. Related Content:
- Use of Life Support and Outcomes Among Patients Admitted to Intensive Care Units
The incidence of invasive group A streptococcal infections has risen in the US. Similar observations have been reported in other parts of the world. Authors Joshua Osowicki, MBBS, PhD, of Murdoch Children’s Research Institute and Theresa L. Lamagni, MSc, PhD, of the United Kingdom Health Security Agency join JAMA Deputy Editor Preeti Malani, MD, MSJ, to discuss the public health challenge posed by group A strep. Related Content:
- Invasive Group A Streptococcal Disease in the US
- Invasive Group A Streptococcal Infections in 10 US States
Less than 20% of patients eligible for lung cancer screening get screened in the US. A recent study examined whether adults eligible for lung cancer screening engage in screening for other types of cancer. Coauthor Chi-Fu Jeffrey Yang, MD, of Harvard Medical School joins JAMA Deputy Editor Tracy Lieu, MD, to discuss. Related Content:
- Preventive Health Care Use Among Adults Eligible for Lung Cancer Screening in the US
Despite increased participation in US long-distance running races, cardiac arrest incidence remains stable. Authors Jonathan Kim, MD, MSc, of Emory University, and Aaron Baggish, MD, of the University of Lausanne Switzerland, discuss the RACER 2 study and compare results with initial findings published in the RACER 1 study from 13 years ago, with JAMA Associate Editor Gregory Marcus, MD, MAS. Related Content:
- Cardiac Arrest During Long-Distance Running Races
ARDS, which is characterized by hypoxemic respiratory failure and inflammatory injury to the lungs, has a mortality rate of 30% to 40%. Balasubramanian Venkatesh, MD, of the George Institute for Global Health joins JAMA Deputy Editor Kristin Walter, MD, MS, to discuss the effects of inhaled sedation with sevoflurane for patients with moderate to severe ARDS. Related Content:
- Sevoflurane Sedation in Acute Respiratory Distress Syndrome
- Inhaled Sedation in Acute Respiratory Distress Syndrome
The US Food and Drug Administration (FDA) issued new draft regulatory guidance for pulse oximeters related to skin pigment. The guidance is a step forward but it may have unintended consequences. Authors Michael Lipnick, MD, and Philip Bicker, MD, PhD, professors of anesthesia at University of California, San Francisco, discuss this and more with JAMA Executive Editor Gregory Curfman, MD. Related Content:
- Pulse Oximetry and Skin Pigmentation—New Guidance From the FDA
- Adherence to FDA Guidance on Pulse Oximetry Testing Among Diverse Individuals, 1996-2024
- Addressing Racial and Ethnic Bias in Pulse Oximeters—A Wicked Problem
- Evaluating the Accuracy of Pulse Oximetry in Children According to Race
The CAUGHT-CAD randomized clinical trial sought to determine whether a CAC score-informed strategy could slow the progression of coronary plaque volume. Author Thomas H. Marwick of the Baker Heart & Diabetes Institute joins JAMA Associate Editor Pradeep Natarajan to discuss "Effects of Combining Coronary Calcium Score With Treatment on Plaque Progression in Familial Coronary Artery Disease." Related Content:
- Effects of Combining Coronary Calcium Score With Treatment on Plaque Progression in Familial Coronary Artery Disease
- Cardiac CT Calcium Score
- Coronary Artery Calcium Testing—Too Early, Too Late, Too Often
- Filling the Evidence Gaps Toward a Coronary Artery Calcium-Guided Primary Prevention Strategy
The HEALEY ALS platform is an innovative first attempt at platform trials in ALS, looking to slow ALS disease progression. Author Sabrina Paganoni, MD, PhD, of Massachusetts General Hospital and Harvard Medical School, discusses results of the first 4 drug regimens from this platform trial and how this study design makes efficient use of resources, with JAMA Deputy Editor Christopher Muth, MD. Related Content:
- Platform Clinical Trials for the Efficient Evaluation of Multiple Treatments
- Pridopidine in Amyotrophic Lateral Sclerosis
- Platform Trials in ALS
- Verdiperstat in Amyotrophic Lateral Sclerosis
- Efficacy and Safety of Zilucoplan in Amyotrophic Lateral Sclerosis
- CNM-Au8 in Amyotrophic Lateral Sclerosis
Understanding health conditions with the most spending and variation across locations and over time is important for identifying trends, inequalities, and strategies for lowering health spending. Joseph Dieleman, PhD, of the University of Washington speaks with JAMA Associate Editor Karen Joynt Maddox, MD, MPH, about county-level variation in health care spending across the US. Related Content:
- Tracking US Health Care Spending by Health Condition and County
Two recent studies published in JAMA provide evidence about the effects of state-level abortion restrictions on birth rates and infant mortality. Author Alyssa Bilinski, PhD, MSc, of Brown University School of Public Health joins JAMA Deputy Editor Tracy Lieu, MD, to discuss her related Editorial "Abortion May Be Controversial—Supporting Children and Families Need Not Be." Related Content:
- Abortion May Be Controversial—Supporting Children and Families Need Not Be
Contemporary models of dementia care are multidisciplinary and aim to bridge medical and social services. Julie P. W. Bynum, MD, MPH, of the University of Michigan speaks with JAMA Deputy Editor Christopher C. Muth, MD, about 2 trials—the D-CARE and IN-PEACE trials—that evaluated care models to support people diagnosed with dementia and their caregivers. Related Content:
- Challenges and Innovations in Dementia Care—Evaluating Comprehensive Models
- Health System, Community-Based, or Usual Dementia Care for Persons With Dementia and Caregivers
- Palliative Care Program for Community-Dwelling Individuals With Dementia and Caregivers
Two new trials published in JAMA evaluate the efficacy of periprocedural intra-arterial thrombolytics after successful endovascular thrombectomy for patients with acute ischemic stroke. Diederik Dippel, MD, PhD, of Erasmus University Medical Center discusses this and more with JAMA Deputy Editor Christopher C. Muth, MD. Related Content:
- Intra-Arterial Thrombolytics During Thrombectomy for Ischemic Stroke—End of the Story or a New Beginning?
- Intra-Arterial Tenecteplase Following Endovascular Reperfusion for Large Vessel Occlusion Acute Ischemic Stroke
- Intra-Arterial Urokinase After Endovascular Reperfusion for Acute Ischemic Stroke
Private equity acquisitions of health care facilities have rapidly increased over the past decade. However, little is known about the effects of these acquisitions on patient experience. Author Rishi K. Wadhera, MD, MPP, MPhil, of Harvard Medical School discusses this topic with JAMA Associate Editor Karen Joynt Maddox, MD, MPH. Related Content:
- Changes in Patient Care Experience After Private Equity Acquisition of US Hospitals
Certain CD4+ T-cell subtypes play a role in asthma. Characterizing asthma endotypes in diverse groups is important to help develop effective therapies for youth with asthma. Author Juan C. Celedon, MD, DrPH, University of Pittsburgh, Department of Pediatrics, discusses this and more with JAMA Deputy Editor Kristin L. Walter, MD, MS. Related Content:
- Transcriptomic Profiles in Nasal Epithelium and Asthma Endotypes in Youth
Most Medicare Advantage (MA) plans offer dental care coverage as a supplemental benefit. However,few beneficiaries are enrolled in an MA plan that provides comprehensive dental benefits. Lisa Simon, MD, DMD, discusses this and more with JAMA Deputy Editor Kristin L. Walter, MD, MS. Related Content:
- Availability of Dental Benefits Within Medicare Advantage Plans by Enrollment and County
Long COVID is now defined as a heterogeneous, infection-associated chronic condition present for at least 3 months after SARS-CoV-2 infection. Author Leora Horwitz, MD, MHS, of NYU Grossman School of Medicine joins JAMA Executive Editor Gregory Curfman, MD, to discuss the JAMA article "2024 Update of the RECOVER-Adult Long COVID Research Index." Related Content:
- 2024 Update of the RECOVER-Adult Long COVID Research Index
- Characterizing Long COVID in Children and Adolescents
Triple-negative breast cancer accounts for around 15% of breast cancers. Zhi-Ming Shao, MD, of Fudon University, joins JAMA Oncology Editor in Chief and JAMA Deputy Editor Nora Disis, MD, to discuss "Camrelizumab vs Placebo in Combination With Chemotherapy as Neoadjuvant Treatment in Patients with Early or Locally Advanced Triple-Negative Breast Cancer: The CamRelief Randomized Clinical Trial." Related Content:
- Camrelizumab vs Placebo in Combination With Chemotherapy as Neoadjuvant Treatment in Patients With Early or Locally Advanced Triple-Negative Breast Cancer
New antiretroviral drugs and formulations continue to become available for the prevention and management of HIV infection. Author Rajesh T. Gandhi, MD, joins JAMA Deputy Editor Preeti Malani, MD, MSJ, to discuss these new approaches for HIV. Related Content:
- Antiretroviral Drugs for Treatment and Prevention of HIV in Adults: 2024 Recommendations of the International Antiviral Society–USA Panel
- Advances in Treatment and Prevention of HIV
A new JAMA study examines the association between severe maternal morbidity in a first birth and the probability of a subsequent birth. Authors Neda Razaz, PhD, and Eleni Tsamantioti, MD, MMedSc, both from the Karolinska Institute in Sweden, discuss this and more with JAMA Associate Editor Melissa A. Simon, MD, MPH. Related Content:
- Association of Severe Maternal Morbidity With Subsequent Birth
- Severe Maternal Morbidity and Subsequent Birth—Understanding and Informing a Woman’s Choice
Elevated lipoprotein(a) levels increase the risk of atherosclerotic cardiovascular disease (ASCVD) and aortic stenosis. Cleveland Clinic’s Steven E. Nissen, MD, speaks with JAMA Executive Editor Gregory Curfman, MD, about how zerlasiran produced more than 80% reductions in time-averaged lipoprotein(a) concentration. Related Content:
- Zerlasiran—A Small-Interfering RNA Targeting Lipoprotein(a)
Preterm birth is the greatest cause of neonatal mortality and morbidity, with infants born extremely preterm at highest risk. Author Brett J. Manley, PhD, the Royal Women’s Hospital, Melbourne, Australia, discusses a new study of the effect of intratracheal corticosteroid administration on survival free of bronchopulmonary dysplasia in preterm infants, with JAMA Deputy Editor Tracy A. Lieu, MD, MPH. Related Content:
- Intratracheal Budesonide Mixed With Surfactant for Extremely Preterm Infants
Preventing obesity in early childhood is challenging for clinicians and families. Authors Eliana M. Perrin, MD, MPH, of Johns Hopkins University, and William J. Heerman, MD, MPH, of Vanderbilt University, join JAMA Deputy Editor Tracy Lieu, MD, to discuss "A Digital Health Behavior Intervention to Prevent Childhood Obesity: The Greenlight Plus Randomized Clinical Trial." Related Content:
- A Digital Health Behavior Intervention to Prevent Childhood Obesity
A new study published in JAMA found that drug-related supply chain issue reports were 40% less likely to result in meaningful drug shortages in Canada compared with the US. Authors Kate Suda, PharmD, MS, of University of Pittsburgh School of Medicine, and Mina Tadrous, PharmD, PhD, of University of Toronto, discuss this and more with JAMA Deputy Editor Joseph S. Ross, MD, MHS. Related Content:
- Differences in Drug Shortages in the US and Canada
- Understanding Drug Supply Shortages in the US and Canada
In the US, childbirth typically occurs in hospitals or accredited birth centers. President of the American College of Obstetricians and Gynecologists Stella Marie Dantas, MD, speaks with JAMA Deputy Editor Linda Brubaker, MD, MS, about newly proposed advanced birth centers that would permit higher-risk births, with concerns for patient safety and rural obstetric care access. Related Content:
- Advanced Birth Centers and the Effect on Maternity Care
The Declaration of Helsinki originated in 1964, developed by the World Medical Association (WMA). Process Chair Jack S. Resneck Jr, MD, discusses the 2024 updates to the Declaration of Helsinki with JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS. Related Content:
- Revisions to the Declaration of Helsinki on Its 60th Anniversary
- World Medical Association Declaration of Helsinki
- Making the Ethical Oversight of All Clinical Trials Fit for Purpose
- The Revised Declaration of Helsinki—Considerations for the Future of Artificial Intelligence in Health and Medical Research
- Revisiting the Declaration of Helsinki—A Patient-Centered Perspective
- Future-Proofing Research Ethics—Key Revisions of the Declaration of Helsinki 2024
- The Revision of the Declaration of Helsinki Viewed From the Americas—Paving the Way to Better Research
- Declaration of Helsinki—Revisions for the 21st Century
- Facilitating Efficient and Ethical Trials at the Intersection of Research and Clinical Care
- The 2024 Revision to the Declaration of Helsinki
Transfusion strategy for patients with acute brain injury, telehealth care, acute kidney injury after cardiac surgery, and weaning ventilatory support are the topics of 4 trials published in JAMA and presented at the 2024 European Society of Intensive Care Medicine meeting. JAMA Associate Editor Christopher Seymour, MD, MSc, joins Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, to discuss. Related Content:
- Shifting Balance of the Risk-Benefit of Restrictive Transfusion Strategies in Neurocritically Ill Patients—Is Less Still More?
- Evaluating Complex Technological Innovations in Critical Care—Current Challenges and Future Directions
- Impact of Adsorptive Blood Purification on Kidney Outcomes
- Ventilator Weaning Strategies—Managing Interaction Between Randomized Treatments
- Restrictive vs Liberal Transfusion Strategy in Patients With Acute Brain Injury
- Effect of Tele-ICU on Clinical Outcomes of Critically Ill Patients
- Extracorporeal Blood Purification and Acute Kidney Injury in Cardiac Surgery
- Frequency of Screening and Spontaneous Breathing Trial Techniques
Gastric cancer is a leading cause of cancer death globally. Chronic H pylori infection is the primary cause of gastric cancer, responsible for at least 80% of the new cases. Constanza Camargo, PhD, of the National Cancer Institute joins JAMA Associate Editor John M. Inadomi, MD, to discuss co-testing with FIT and H pylori stool antigen to help prevent gastric cancer. Related Content:
- Fecal Immunochemical Test and Helicobacter pylori Stool Antigen Co-Testing
- Screening for Helicobacter pylori to Prevent Gastric Cancer
Fever is associated with worse outcomes in patients with stroke, but whether preventing fever improves outcomes is unclear. David M. Greer, MD, MA, speaks with JAMA Associate Editor Jeffrey L. Saver, MD, about fever prevention in patients with acute stroke and its impact on functional outcomes. Related Content:
- Fever Prevention in Patients With Acute Vascular Brain Injury
- Feasibility of Fever Prevention in Vascular Brain Injury
The 2024 Lasker–DeBakey Clinical Medical Research Award has been presented for the discovery of GLP-1 and its application to the treatment of obesity. Lasker winner Svetlana Mojsov, PhD, discusses her role in this innovative discovery and more with JAMA Senior Editor Anne Rentoumis Cappola, MD, ScM. Related Content:
- Chemistry Matters—From a Putative Peptide to Effective Treatments for Diabetes and Obesity
- Discovery of cGAS as a DNA-Sensing Enzyme That Triggers Inflammation
- GLP-1 for Treating Obesity—Origin, History, and Evolution
- AIDS in Africa—Impact of Research
Palliative care is an essential component to high-quality care for patients with cancer. How can access to palliative care be expanded? Eduardo Bruera, MD, from MD Anderson Cancer Center speaks with JAMA Editor in Chief Kirsten Bibbins-Domingo about 2 new trials in JAMA that address access to care and what more it will take for executives, insurers, and regulators to support palliative care programs. Related Content:
- Improving Palliative Care Access for Patients With Cancer
- Telehealth vs In-Person Early Palliative Care for Patients With Advanced Lung Cancer
A new trial assessed whether balloon angioplasty plus aggressive medical management was superior to aggressive medical management alone for patients with symptomatic intracranial atherosclerotic stenosis. Author Zhongrong Miao, MD, PhD, from Beijing Tiantan Hospital, discusses the BASIS randomized clinical trial with JAMA Deputy Editor Christopher C. Muth, MD. Related Content:
- Balloon Angioplasty vs Medical Management for Intracranial Artery Stenosis
- Is Balloon Angioplasty the Future for Intracranial Stenosis?
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The abating COVID-19 pandemic brings attention to rising mortality rates from non-COVID causes in the US, a trend that predates the COVID-19 pandemic. Viewpoint author Steven H. Woolf, MD, MPH, discusses this and more with JAMA Executive Editor Gregory Curfman, MD. Related Content:
- Increasing Mortality Rates in the US, but Not From COVID-19
Nonhormonal treatments for menopausal vasomotor symptoms may benefit symptomatic patients who cannot take or prefer to avoid systemic hormones. Author JoAnn V. Pinkerton, MD, MSCP, discusses the efficacy and safety of elinzanetant for the treatment of moderate to severe vasomotor symptoms associated with menopause with JAMA Deputy Editor Linda Brubaker, MD, MS. Related Content:
- Elinzanetant for the Treatment of Vasomotor Symptoms Associated With Menopause
- A New Era in Menopause Management?
To address the need to characterize long COVID in children and adolescents, the National Institutes of Health funded a pediatric program in the Researching COVID to Enhance Recovery (RECOVER) Initiative. Editorialist Suchitra Rao, MBBS, MSCS, University of Colorado School of Medicine and Children’s Hospital Colorado, Aurora, discusses this and more with JAMA Senior Editor Tracy A. Lieu, MD, MPH. Related Content:
- Uncovering Long COVID in Children
- Characterizing Long COVID in Children and Adolescents
A new study looks at uterus transplant to determine if it is safe, feasible, and results in births of healthy infants. Editorialist Emily Jungheim, MD, MSCI, Northwestern University, discusses this innovative treatment with JAMA Deputy Editor Linda Brubaker, MD, MS. Related Content:
- Uterus Transplant—The Frontier of Innovative Fertility Treatment
- Uterus Transplant in Women With Absolute Uterine-Factor Infertility
Ten percent of US adolescents use e-cigarettes, and many want to quit. However, evidence on the effectiveness of vaping cessation interventions is lacking. Amanda L. Graham, PhD, of the Truth Initiative discusses with JAMA Senior Editor Tracy Lieu, MD, MPH, how a tailored, interactive text message intervention increased vaping cessation among adolescents recruited via social media channels. Related Content:
- A Vaping Cessation Text Message Program for Adolescent E-Cigarette Users
- Supporting Adolescents’ Desire to Quit E-Cigarettes
- What Are E-Cigarettes?
- Variability in Constituents of E-Cigarette Products Containing Nicotine Analogues
- E-Cigarette Use in Adults
- Controversial FDA Decision Authorizes Menthol-Flavored E-Cigarettes Despite Risks to Youth
- Vaping in Youth
- E-Cigarette Use in Adolescents and Adults—A JAMA Collection
Gestational age estimation is foundational for obstetric care. In resource-limited settings, an integrated AI tool allows novice users to improve gestational age estimates. Author Jeffrey Stringer, MD, University of North Carolina, joins JAMA Deputy Editor Linda Brubaker, MD, MS, to discuss Diagnostic Accuracy of an Integrated AI Tool to Estimate Gestational Age From Blind Ultrasound Sweeps. Related Content:
- Diagnostic Accuracy of an Integrated AI Tool to Estimate Gestational Age From Blind Ultrasound Sweeps
- Enhancing Obstetric Ultrasonography With Artificial Intelligence in Resource-Limited Settings
Biomarkers for Alzheimer disease (AD) provide insight into disease processes and may aid clinical diagnosis for individuals with cognitive impairment. Author Stephen Salloway, MD, MS, of Brown University joins JAMA Deputy Editor Christopher Muth, MD, to discuss 2 articles and an accompanying editorial about blood biomarkers for AD and potential implications for clinical practice. Related Content:
- Are Blood Tests for Alzheimer Disease Ready for Prime Time?
- Blood Biomarkers to Detect Alzheimer Disease in Primary Care and Secondary Care
- Changes in Alzheimer Disease Blood Biomarkers and Associations With Incident All-Cause Dementia
Ulcerative colitis can significantly decrease quality of life. A third of patients have persistent symptoms with tumor necrosis factor inhibitors and nearly 1 in 5 patients will be hospitalized within 5 years of diagnosis. Author Gilaad G. Kaplan, MD, MPH, of the University of Calgary joins JAMA Associate Editor John M. Inadomi, MD, to discuss Risankizumab for Ulcerative Colitis. Related Content:
- Monoclonal Antibody Risankizumab for Ulcerative Colitis
- Risankizumab for Ulcerative Colitis
What are the ovarian cancer risks associated with endometriosis subtypes? Author Karen C. Schliep, PhD, MSPH, of the University of Utah joins JAMA Deputy Editor Linda Brubaker, MD, MS, to discuss Endometriosis Typology and Ovarian Cancer Risk. Related Content:
- Endometriosis Typology and Ovarian Cancer Risk
- New Insights in Endometriosis Subtypes and Ovarian Cancer Risk
Oral nicotine pouches are becoming more popular in the US, based on a survey performed in 2022. Hongying Daisy Dai, PhD, from Nebraska Medical Center, Omaha, discusses nicotine pouches and more with JAMA Deputy Editor Kristin L. Walter, MD, MS. Related Content:
- Prevalence of Nicotine Pouch Use Among US Adults
Availability of pediatric care is decreasing, despite the growing complexity of pediatric care needs. Match rates for pediatric residency continue to decline. The US risks a serious shortage of pediatricians. Julie Byerley, MD, MPH, executive vice president & chief academic officer, Geisinger, Pennsylvania, discusses this and more with JAMA Deputy Editor Linda Brubaker, MD, MS. Related Content:
- Where Are All the Pediatricians?
Facilitating safe and timely health care for individuals planning medication abortion is a reproductive health care priority. Lauren J. Ralph, PhD, MPH, and Daniel Grossman, MD, of University of California San Francisco join JAMA Deputy Editor Linda Brubaker, MD, MS, to discuss Comparison of Effectiveness of No-Test Telehealth and In-Person Medication Abortion. Related Content:
- Comparison of No-Test Telehealth and In-Person Medication Abortion
Can a new ECG finding identify individuals at risk for dying suddenly? Jason D. Roberts, MD, of McMaster University joins JAMA Associate Editor Gregory M. Marcus, MD, MAS, to discuss A Clinical Diagnostic Test for Calcium Release Deficiency Syndrome (CRDS). CRDS is a recently described cause of sudden arrhythmic death. Until now, no clinical test has existed to identify those with the disease. Related Content:
- A Clinical Diagnostic Test for Calcium Release Deficiency Syndrome
- The First Clinical Test for Calcium Release Deficiency Syndrome?
Joel M. Dulhunty, MD, PhD, Royal Brisbane and Women’s Hospital, and Jason A. Roberts, BPharm, PhD, University of Queensland Centre for Clinical Research, join JAMA Deputy Editor Preeti Malani, MD, MSJ, to discuss the BLING trial that assessed continuous vs intermittent β-lactam antibiotic infusions in patients with sepsis or septic shock. Related Content:
- Continuous vs Intermittent β-Lactam Antibiotic Infusions in Critically Ill Patients With Sepsis
- Prolonged vs Intermittent Infusions of β-Lactam Antibiotics in Adults With Sepsis or Septic Shock
Randomized clinical trials (RCTs) frequently fail to generate knowledge relevant to practice, while practice patterns are frequently unsupported by RCT evidence. Derek C. Angus, MD, MPH, of the University of Pittsburgh, joins JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, to discuss The Integration of Clinical Trials With the Practice of Medicine: Repairing a House Divided. Related Content:
- The Integration of Clinical Trials With the Practice of Medicine
Forced nitrogen inhalation was used by the state of Alabama to execute Kenneth Smith on January 25, 2024. Some politicians, attorneys general, and health care practitioners support its use for capital punishment in the US. Philip E. Bickler, MD, PhD, and Michael S. Lipnick, MD, discuss the evidence indicating that forced nitrogen inhalation is inhumane with JAMA Executive Editor Gregory Curfman, MD. Related Content:
- Evidence Against Use of Nitrogen for the Death Penalty
Guidelines call for better evidence on the health outcomes after living kidney donation. Author Amit X. Garg, MD, PhD, London Health Sciences Centre, and editorialist Elizabeth C. Lorenz, MD, Baylor College of Medicine, discuss a new study that compares the risks of hypertension and other health outcomes in living kidney donors, with JAMA Associate Editor Wolfgang Winkelmayer, MD, ScD. Related Content:
- Hypertension and Kidney Function After Living Kidney Donation
- Prospectively Examining Outcomes After Living Kidney Donation
- Kidney Transplant Outcomes From Deceased Donors Who Received Dialysis
- Expanding the Overton Window in Deceased Kidney Donor Eligibility—Enough to Make a Difference?
What is the natural history and cardiovascular burden of the V142I transthyretin variant among US Black individuals who carry this variant? Senthil Selvaraj, MD, MS, MA, from Duke University, and Scott D. Solomon, MD, from Brigham and Women’s Hospital, discuss this and more with JAMA Executive Editor Gregory Curfman, MD. Related Content:
- Cardiovascular Burden of the V142I Transthyretin Variant
- Addressing Health Disparities—The Case for Variant Transthyretin Cardiac Amyloidosis Grows Stronger
- Heart Failure in African American Individuals, Version 2.0
- Cardiac Amyloidosis Due to Transthyretin Protein
Between 2019 and 2021, pediatric mortality rates had the largest increases in at least half a century. Steven H. Woolf, MD, MPH, of Virginia Commonwealth University Center on Society and Health, joins JAMA Associate Editor Tracy A. Lieu, MD, MPH, to discuss how racial and ethnic disparities and specific causes have factored into these increases and what this means for policymakers and clinicians. Related Content:
- Racial and Ethnic Disparities in All-Cause and Cause-Specific Mortality Among US Youth
- Injury Prevention Science and Firearm Injury in Pediatric Health
When initial treatment with varenicline or nicotine replacement doesn't work, does increasing dosage improve smoking cessation rates? Paul Cinciripini, PhD, of MD Anderson Cancer Center's Department of Behavioral Science, joins JAMA Executive Editor Gregory Curfman, MD, to discuss guidance on the best strategies for smoking cessation following an initial quit attempt. Related Content:
- Smoking Cessation After Initial Treatment Failure With Varenicline or Nicotine Replacement
Extensive evidence documents health disparities for lesbian, gay, and bisexual (LGB) women, including worse physical, mental, and behavioral health than heterosexual women. Sarah McKetta, ScM, MD, PhD, discusses these factors and their link to premature mortality with JAMA Deputy Editor Linda Brubaker, MD, MS. Related Content:
- Disparities in Mortality by Sexual Orientation in a Large, Prospective Cohort of Female Nurses
Can real-time EHR–generated recommendations safely reduce antibiotic use in hospitalized patients with pneumonia or UTI? Shruti K. Gohil, MD, MPH, of the University of California-Irvine, joins JAMA Deputy Editor Preeti Malani, MD, MSJ, to discuss the INSPIRE randomized clinical trial. Related Content:
- Stewardship Prompts to Improve Antibiotic Selection for Pneumonia
- Stewardship Prompts to Improve Antibiotic Selection for Urinary Tract Infection
- Harnessing the Electronic Health Record to Improve Empiric Antibiotic Prescribing
Climate action is an urgent public health imperative. Climate change is causing excess morbidity and mortality and posing an increasing threat to mental health and well-being. The US health care sector is a significant contributor to this problem. A. Eugene Washington, MD, of Duke University, discusses accelerating climate action with JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS. Related Content:
- Accelerating Climate Action Through Academic Health Systems
The utility of prostate-specific antigen (PSA) screening for prostate cancer detection is impacted by detection of cancers with low risk of mortality. Editorialist Jeffrey J. Tosoian, MD, MPH, discusses a pragmatic approach to prostate cancer screening with JAMA Deputy Editor Mary L. (Nora) Disis, MD. Related Content:
- A Pragmatic Approach to Prostate Cancer Screening
- Prostate Cancer Screening With PSA, Kallikrein Panel, and MRI
- Prostate-Specific Antigen Screening and 15-Year Prostate Cancer Mortality
Infections due to multidrug-resistant organisms (MDROs) are difficult to treat with increased morbidity, mortality, length of hospitalization, and health care costs. Author Susan S. Huang, MD, MPH, from the University of California Irvine School of Medicine, joins JAMA Deputy Editor Preeti Malani, MD, MSJ, to discuss a new study that used a regional intervention to prevent MDROs. Related Content:
- Reducing Hospitalizations and Multidrug-Resistant Organisms via Regional Decolonization in Hospitals and Nursing Homes
The US Supreme Court will soon decide a case challenging the US Food and Drug Administration’s (FDA’s) approval of mifepristone. Author Holly Fernandez Lynch, JD, MBE, University of Pennsylvania, joins JAMA Executive Editor Gregory Curfman, MD, to discuss the science and politics surrounding this significant case. Related Content:
- The FDA in the Crosshairs—Science, Politics, and Abortion
- Provision of Medications for Self-Managed Abortion Before and After the Dobbs v Jackson Women’s Health Organization Decision
- Understanding the Impacts of the Supreme Court Case FDA v Alliance for Hippocratic Medicine
How did GPT-4 Vision, a model that can work with images and text as input, perform when answering clinical challenge questions from medical journals? Daniel Truhn, MD, MSc, of the University Hospital Aachen in Germany, joins JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, to discuss this topic. Related Content:
- Comparative Analysis of Multimodal Large Language Model Performance on Clinical Vignette Questions
An observational study by Lin Li, PhD, and colleagues, published in JAMA, found that pharmacotherapy was associated with reduced mortality in individuals with ADHD. Frances R. Levin, MD, of the Columbia Vagelos College of Physicians and Surgeons, who wrote an accompanying editorial, joins JAMA Associate Editor Donald C. Goff, MD, to discuss the results of this article. Related Content:
- Treating Attention-Deficit/Hyperactivity Disorder Matters
Introducing JAMA's new Communicating Medicine series, JAMA Associate Editor Anne Cappola, MD, ScM, discusses strategies for delivering effective messages in the patient encounter with authors Joseph Cappella, PhD, of the University of Pennsylvania, and Richard Street, PhD, of Texas A&M University and Baylor College of Medicine. Related Content:
- Delivering Effective Messages in the Patient-Clinician Encounter
How will new study results inform HIV prevention in the US and globally? JAMA Deputy Editor Preeti Malani, MD, MSJ, and author Jeanne Marrazzo, MD, MPH, director of NIAID, discuss these study findings and more. Related Content:
- HIV Preexposure Prophylaxis With Emtricitabine and Tenofovir Disoproxil Fumarate Among Cisgender Women
JAMA Associate Editor Romain Pirracchio, MD, MPH, discusses context and implications of the new pediatric sepsis criteria with authors Hallie Prescott, MD, MSc, of the University of Michigan and Ann Arbor VA Hospital, and Roberto Jabornisky, MD, of Northeastern National Medical School in Argentina. Related Content:
- Context and Implications of the New Pediatric Sepsis Criteria
- Transitioning From SIRS to Phoenix With the Updated Pediatric Sepsis Criteria—The Difficult Task of Simplifying the Complex
Renters who received eviction filings experienced excess mortality associated with the COVID-19 pandemic. JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, discusses a recent study that underscores the importance of studying health outcomes among marginalized populations with author Nick Graetz, PhD, from Princeton University. Related Content:
- Examining Excess Mortality Associated With the COVID-19 Pandemic for Renters Threatened With Eviction
Childhood death rates remain high in some areas of sub-Saharan Africa, despite global reductions in childhood mortality. JAMA Deputy Editor Preeti Malani, MD, MSJ, and author Thomas Lietman, MD, University of California, San Francisco, discuss twice-yearly azithromycin to reduce childhood mortality. Related Content:
- Mass Azithromycin Distribution to Prevent Child Mortality in Burkina Faso
Bivalent mRNA COVID-19 vaccines were recommended for children and adolescents aged 5 to 17 years in the US, but were they effective? JAMA Associate Editor Tracy A. Lieu, MD, MPH, spoke with author Leora R. Feldstein, PhD, US Centers for Disease Control and Prevention, about the effectiveness of bivalent COVID-19 vaccines in children and adolescents. Related Content:
- Effectiveness of Bivalent mRNA COVID-19 Vaccines in Preventing SARS-CoV-2 Infection in Children and Adolescents Aged 5 to 17 Years
Following the Dobbs decision, females aged 18-45 years living in states with “trigger laws” that restricted access to abortion reported a greater increase in symptoms of anxiety and depression than those in states without trigger laws. JAMA Associate Editor Donald Goff, MD, speaks with editorialist Julia Steinberg, PhD, associate professor at the School of Public Health at the University of Maryland, about this topic. Related Content:
- Mental Health Symptoms When Abortion Access Is Restricted
- Anxiety and Depression Symptoms After the Dobbs Abortion Decision
JAMA Deputy Editor Preeti Malani, MD, MSJ, and author Alexander K. Smith, MD, MS, MPH, University of California, San Francisco, discuss the importance of 2 new palliative care trials that were recently published in JAMA. Related Content:
- A Tale of 2 Palliative Care Trials
- Association of Receipt of Palliative Care Interventions With Health Care Use, Quality of Life, and Symptom Burden Among Adults With Chronic Noncancer Illness
Dialysis facilities in the US are financially rewarded for higher rates of home dialysis and kidney transplant, but facilities that serve patients with high social risk might have a harder time meeting these goals. JAMA Associate Editor Karen E. Joynt Maddox, MD, MPH, speaks with Amal N. Trivedi, MD, MPH, of Brown University, about how this plays out under the ESRD Treatment Choices Model. Related Content:
- Social Risk and Dialysis Facility Performance in the First Year of the ESRD Treatment Choices Model
Alpha-gal syndrome is a food allergy to red meat products that develops after affected individuals are bitten by a tick. JAMA Deputy Editor Kristin Walter, MD, MS, discusses alpha-gal syndrome with author Mariel R. Benjamin, MD, assistant professor in the Division of Allergy and Clinical Immunology at Michigan Medicine. Related Content:
- What Is Alpha-Gal Syndrome?
The effects of private equity acquisition of US hospitals on the quality of inpatient care and patient outcomes remain largely unknown. JAMA Associate Editor Karen E. Joynt Maddox, MD, MPH, spoke with author Zirui Song, MD, PHD, of Massachusetts General Hospital, about a recent study showing that private equity acquisition was associated with increased hospital-acquired adverse events. Related Content:
- Changes in Hospital Adverse Events and Patient Outcomes Associated With Private Equity Acquisition
Does reducing dietary sodium benefit patients already taking antihypertensive medication? JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, speaks with author Norrina Allen, PhD, MPH, from Northwestern University, about the effect of dietary sodium on blood pressure. Related Content:
- Effect of Dietary Sodium on Blood Pressure
Cannabis use is increasing among reproductive-age individuals. JAMA Deputy Editor Linda Brubaker, MD, MS, discusses the associated risks of cannabis exposure during pregnancy with Torri D. Metz, MD, MS, University of Utah Health. Related Content:
- Cannabis Exposure and Adverse Pregnancy Outcomes Related to Placental Function
Bilateral renal agenesis results in lethal neonatal pulmonary hypoplasia. New evidence from an amnioinfusion trial is available. JAMA Deputy Editor Linda Brubaker, MD, MS, discusses the results from the Renal Anhydramnios Fetal Therapy Trial with Meredith A. Atkinson, MD, MHS, Johns Hopkins University, and Johnathan M. Davis, MD, Tufts University. Related Content:
- Neonatal Survival After Serial Amnioinfusions for Bilateral Renal Agenesis
Cervical cancer screening is effective when done as recommended. JAMA Deputy Editor Linda Brubaker, MD, speaks with Rachel L. Winer, PhD, MPH, of the University of Washington, about a recent trial in JAMA that compared cervical cancer screening strategies, including direct-mail and opt-in approaches for human papillomavirus (HPV) self-sampling. Related Content:
- Strategies to Increase Cervical Cancer Screening With Mailed Human Papillomavirus Self-Sampling Kits
Small-volume blood collection tubes may decrease red blood cell transfusions in intensive care units without affecting laboratory analysis. JAMA Associate Editor Christopher W. Seymour, MD, MSc, discusses the results and implications of the STRATUS trial with Deborah M. Siegal, MD, MSc, of Ottawa Hospital Research Institute. Related Content:
- Small-Volume Blood Collection Tubes to Reduce Transfusions in Intensive Care
Fitness trackers are a group of devices including watches, phones, and rings that track physical activity. JAMA Executive Editor Gregory Curfman, MD, speaks with I-Min Lee, MBBS, ScD, professor of medicine at Harvard Medical School and professor of epidemiology at Harvard T.H. Chan School of Public Health, about using fitness trackers to guide advice on activity prescription. Related Content:
- Fitness Trackers to Guide Advice on Activity Prescription
JAMA Senior Editor Kristin Walter, MD, MS, and Lawrence O. Gostin, JD, JAMA Legal and Global Health Correspondent and Faculty Director of the O’Neill Institute for National and Global Health Law at Georgetown University, discuss the Inflation Reduction Act, which for the first time allows the Centers for Medicare & Medicaid Services to negotiate prescription drug prices with drug manufacturers. Related Content:
- Medicare’s Historic Prescription Drug Price Negotiations
JAMA Executive Editor Gregory Curfman, MD, speaks with Richard G. Bach, MD, professor of medicine and medical director of the cardiac intensive care unit at the Washington University School of Medicine in St Louis, about the use of traditional Chinese medicine to treat patients with acute ST-segment elevation myocardial infarction. Related Content:
- Traditional Chinese Medicine Meets Evidence-Based Medicine in the Acutely Infarcted Heart
Optical coherence tomography (OCT) is a powerful imaging tool used across multiple clinical disciplines. JAMA Executive Editor Gregory Curfman, MD, speaks with 2023 Lasker Award recipient James G. Fujimoto, PhD, professor of electrical engineering at MIT, about his role in developing OCT and OCT’s advancements in clinical practice. Related Content:
- Optical Coherence Tomography—History, Evolution, and Future Prospects
Nasal mupirocin plus chlorhexidine baths in ICUs prevents methicillin-resistant Staphylococcus aureus (MRSA) infections but raises concern about antibiotic resistance. JAMA Senior Editor Kristin Walter, MD, speaks with Susan Huang, MD, of University of California, Irvine, about a study comparing iodophor vs mupirocin with chlorhexidine bathing for ICU-attributable S aureus clinical cultures. Related Content:
- Nasal Iodophor Antiseptic vs Nasal Mupirocin Antibiotic in the Setting of Chlorhexidine Bathing to Prevent Infections in Adult ICUs
It’s been unclear whether remote ischemic conditioning (RIC) with transient cycles of limb ischemia and reperfusion is an effective treatment for acute stroke. JAMA Deputy Editor Chris Muth, MD, speaks with author Rolf Blauenfeldt, MD, Aarhus University Hospital, Denmark, about the RESIST randomized clinical trial, which looks at the effect of RIC when initiated in the prehospital setting. Related Content:
- Remote Ischemic Conditioning for Acute Stroke
During the COVID-19 pandemic, the incidence of diabetes in childhood increased. JAMA Associate Editor Anne R. Cappola, MD, ScM, and Ezio Bonifacio, PhD, from the Center for Regenerative Therapies at the Dresden University of Technology, discuss SARS-CoV-2 infection and its association with islet autoimmunity in early childhood. Related Content:
- SARS-CoV-2 Infection and Development of Islet Autoimmunity in Early Childhood
Many premature infants with respiratory distress are now supported with continuous positive airway pressure, or CPAP, rather than intubation and ventilation, and those with CPAP can receive surfactant via a minimally invasive approach. JAMA Associate Editor Tracy Lieu, MD, speaks with author Peter Dargaville, MD, from the Menzies Institute for Medical Research in Tasmania, Australia, about Two-Year Outcomes After Minimally Invasive Surfactant Therapy in Preterm Infants: Follow-Up of the OPTIMIST-A Randomized Clinical Trial. Related Content:
- Two-Year Outcomes After Minimally Invasive Surfactant Therapy in Preterm Infants
There is an established link between sedentary behavior and cardiovascular disease, but the association between sedentary behavior and dementia is unclear. JAMA Deputy Editor Christopher C. Muth, MD, speaks with David A. Raichlen, PhD, University of Southern California, about a new study that investigates the relationship between sedentary behavior and dementia in older adults.
Related Content:
- Sedentary Behavior and Incident Dementia Among Older Adults
In a new study, psilocybin showed promise as a treatment for major depressive disorder (MDD). JAMA Associate Editor Donald C. Goff, MD, speaks with author Charles L. Raison, MD, from the Usona Institute, about the study, as well as Rachel Yehuda, PhD, Mount Sinai School of Medicine, who wrote an accompanying editorial about the potential benefits of psychedelic therapies. Related Content:
- Single-Dose Psilocybin Treatment for Major Depressive Disorder
- Psychedelic Therapy—A New Paradigm of Care for Mental Health
Magnesium sulfate is widely recommended for neuroprotection in pregnancies at risk of preterm delivery. However, the optimal gestational age for use is unclear. JAMA Associate Editor Melissa Simon, MD, MPH, and Caroline Crowther, MD, Liggins Institute, University of Auckland, discuss the use of magnesium sulfate at different gestational ages and potential benefit vs harms as reflected in the MAGENTA Trial.
Related Content:
- Prenatal Intravenous Magnesium at 30-34 Weeks’ Gestation and Neurodevelopmental Outcomes in Offspring
Anthracyclines are used to treat a variety of cancers, but treatment may be limited by cardiac toxicity. JAMA Executive Editor Gregory Curfman, MD, discusses a new clinical trial on the use of atorvastatin to prevent anthracycline-induced cardiac toxicity with authors Tomas Neilan, MD, MPH, and Marielle Scherrer-Crosbie, MD, PhD.
Related Content:
- Atorvastatin for Anthracycline-Associated Cardiac Dysfunction
Cardiovascular health is essential to everyone, but especially important to address in individuals who can become or who are pregnant or postpartum. JAMA Associate Editor Melissa Simon, MD, MPH, and Sadiya S. Khan, MD, MSc, Northwestern University, discuss the importance of cardiovascular health in pregnancy-capable, pregnant, and postpartum persons, how to counsel such individuals, issues of access to care and health equity, and their impact on cardiovascular health.
Related Content:
- Trends in Cardiovascular Health Counseling Among Postpartum Individuals
The performance of whole-genome sequencing in comparison with targeted genomic testing methods is not well understood. In this podcast, JAMA Associate Editor W. Gregory Feero, MD, PHD, interviews author Jill L. Maron, MD, MPH, of the Women and Infants Hospital of Rhode Island about a study of whole-genome sequencing vs a commercially available targeted genetic testing platform for diagnosing ill neonates with suspected genetic conditions.
Related Content:
- Rapid Whole-Genomic Sequencing and a Targeted Neonatal Gene Panel in Infants With a Suspected Genetic Disorder
Bempedoic acid is an effective option for some statin-intolerant patients with an elevated predicted risk of cardiovascular events. However, as JAMA Executive Editor Gregory Curfman, MD, discusses with editorialist Dhruv S. Kazi, MD, MSc, MS, bempedoic acid should not be considered a substitute for statins, which remain the first-line therapy for primary prevention.
Related Content:
- Bempedoic Acid for Primary Prevention of Cardiovascular Events in Statin-Intolerant Patients
- Bempedoic Acid for High-Risk Primary Prevention of Cardiovascular Disease
Valganciclovir is standard cytomegalovirus (CMV) prophylaxis in high-risk kidney transplant recipients, but its use is limited by myelosuppression. JAMA Deputy Editor Preeti Malani, MD, MSJ, interviews Ajit Limaye, MD, from the University of Washington, about a multinational randomized trial of letermovir vs valganciclovir for CMV prevention in CMV-negative patients receiving a kidney from a CMV-positive donor.
Related Content:
- Letermovir vs Valganciclovir for Prophylaxis of Cytomegalovirus in High-Risk Kidney Transplant Recipients
US hospitals report data on numerous quality metrics to government and independent rating organizations, but the cost of doing so is not well known. JAMA Associate Editor Karen E. Joynt Maddox, MD, discusses a new study that examines just how many quality metrics hospitals have to report, and attempts to quantify how much data collection and reporting costs in hours and dollars, with corresponding author Stephen A. Berry MD, PhD, Johns Hopkins University, Baltimore, Maryland.
Related Content:
- The Volume and Cost of Quality Metric Reporting
Interview with Michael Silverstein, MD, MPH, USPSTF chair and coauthor of Screening for Depression and Suicide Risk in Adults, and Screening for Anxiety Disorders in Adults: US Preventive Services Task Force Recommendation Statements. Hosted by JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS.
Related Content:
- Anxiety Screening
- Depression and Suicide Risk Screening
- Screening for Depression and Suicide Risk in Adults
- Screening for Anxiety Disorders in Adults
- Screening for Depression and Suicide Risk in Adults
- Screening for Anxiety Disorders in Adults
- Are There Reasons to Fear Anxiety Screening?
- Reframing the Key Questions Regarding Screening for Suicide Risk
The US Black population experienced more than 80 million excess years of life lost compared with the White population over a recent 22-year period. JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, discusses the research that quantified this disparity with authors César Caraballo, MD, Harlan M. Krumholz, MD, SM, and Clyde W. Yancy, MD, MSc.
Related Content:
- Excess Mortality and Years of Potential Life Lost Among the Black Population in the US, 1999-2020
Intentional miscoding of abortion services may put clinicians and hospital systems at legal risk. JAMA Senior Editor Linda Brubaker, MD, MS, and Carmel Shachar, JD, MPH, from the Petrie-Flom Center for Health Law Policy, Biotechnology, and Bioethics, Harvard Law School, discuss the risks of intentional miscoding practices and possible penalties.
Related Content:
- Abortion Miscoding—Legal Risks for Clinicians and Hospital Systems
The Covenant of Water, Stanford University professor Dr Abraham Verghese’s long-awaited follow-up to his 2009 novel Cutting for Stone, traces the lives of a family in southern India negotiating forces of history, fate, and a genetic condition that takes the life of a member in each generation by drowning. In part 2, JAMA Arts and Medicine Section Editor Michael Berkwits, MD, MSCE, talks with Dr Verghese about the craft of writing fiction, the role of the humanities in medicine, of artificial intelligence in literature, and more. Related Content:
- “The Art of the Craft,” From The Covenant of Water
- The Covenant of Water – Reflections on Fiction, the Humanities, and Medicine (Part 1 of this interview)
The ACA’s preventive services mandate requires insurers to cover, without charge, nearly 200 basic primary care services. But now, a federal judge has issued a nationwide injunction preventing the Biden administration from enforcing this cost-free care for a significant number of these services. JAMA Executive Editor Gregory Curfman, MD, discusses this and more with Abbe R. Gluck, JD, Solomon Center for Health Law & Policy, Yale Law School. Related Content:
- Cost-Free Preventive Care Under the ACA Faces Legal Challenge
Most epidemiological studies of heart failure have been conducted in high-income countries. JAMA Senior Editor Kristin L. Walter, MD, MS, interviews Philip George Joseph, MD, from the Population Health Research Institute, Ontario, Canada, about a study of more than 23 000 patients with heart failure in 40 countries. Related Content:
- Global Variations in Heart Failure Etiology, Management, and Outcomes
Interview with Gbenga Ogedegbe, MD, MPH, USPSTF member and coauthor of Screening for Latent Tuberculosis Infection in Adults: US Preventive Services Task Force Recommendation Statement. Hosted by JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS. Related Content:
- Screening for Latent Tuberculosis Infection in Adults
- Screening for Latent Tuberculosis Infection Among Non–US-Born Adults in the US
- Screening for Latent Tuberculosis Infection in Adults
- Screening for Latent Tuberculosis
The mental health of young people in the US has been an issue of increased concern in recent years. In this podcast, author Tanner Bommersbach, MD, MPH, assistant professor in the Department of Psychiatry and Psychology at the Mayo Clinic in Rochester, Minnesota, and Greg Rhee, PhD, a health services researcher and pharmacoepidemiologist at the University of Connecticut, join JAMA Senior Editor Kristin Walter, MD, MS, in a discussion about mental health-related emergency department visits in the US among children, adolescents, and young adults from 2011-2020. Related Content:
- National Trends in Mental Health–Related Emergency Department Visits Among Youth, 2011-2020
The Covenant of Water, Stanford University professor Dr Abraham Verghese’s long-awaited follow-up to his 2009 novel Cutting for Stone, traces the lives of a family in southern India negotiating forces of history, fate, and a genetic condition that takes the life of a member in each generation by drowning. JAMA Arts and Medicine Section Editor Michael Berkwits, MD, MSCE, talks with Dr Verghese about the novel’s clinical insights, the craft of writing fiction, the role of the humanities in medicine, of artificial intelligence in literature, and more. Related Content:
- “The Art of the Craft,” From The Covenant of Water
Major medical schools are no longer contributing data to the US News & World Report (USNWR) including more than half the schools that are currently ranked in the top 10 medical schools by the survey. In this podcast, JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, speaks with author Holly J. Humphrey, MD, from the Josiah Macy Jr Foundation in New York, about the recently published Viewpoint "Medical School Rankings—Bad for the Health of the Profession and the Public." Related Content:
- Medical School Rankings—Bad for the Health of the Profession and the Public
Differences among countries in how health care is organized could have implications for health equity. JAMA Associate Editor Karen Joynt Maddox, MD, MPH, and Bruce E. Landon, MD, MBA, MSc, professor of health care policy, Harvard Medical School, discuss whether treatment patterns and outcomes for patients presenting with acute myocardial infarction differ for patients with higher vs lower incomes across 6 countries. Related Content:
- Differences in Treatment Patterns and Outcomes of Acute Myocardial Infarction for Low- and High-Income Patients in 6 Countries
JAMA Executive Editor Greg Curfman, MD, speaks with Robert D. Truog, MD, MA, director of the Harvard Center for Bioethics, who describes the 2 approaches to the determination of death (cardiovascular death and brain death) and discusses the possibility that the determination of brain death may soon undergo substantial change, with important implications for organ transplantation. Related Content:
- The Uncertain Future of the Determination of Brain Death
Mary Arakelyan, MPH, and JoAnna Leyenaar, MD, PhD, MPH, vice chair of Research in Pediatrics at Dartmouth, discuss increases in pediatric mental health hospitalizations and suicide-related diagnoses over the past decade. Hosted by JAMA Associate Editor Tracy Lieu, MD, MPH. Related Content: Pediatric Mental Health Hospitalizations at Acute Care Hospitals in the US, 2009-2019. Related Content:
- Pediatric Mental Health Hospitalizations at Acute Care Hospitals in the US, 2009-2019
In 2011, the US Food and Drug Administration (FDA) announced a mandate to limit acetaminophen (paracetamol) to 325 mg/tablet in combination acetaminophen and opioid medications, with manufacturer compliance required by early 2014. In this podcast, JAMA Deputy Editor Mary M. McDermott, MD, interviews Jayme E. Locke, MD, MPH, and Babak J. Orandi, MD, PhD, about their JAMA study describing results of the FDA announcement on subsequent rates of hospitalizations for acute liver failure due to toxicity from acetaminophen-containing opioid drugs. Related Content:
- Association of FDA Mandate Limiting Acetaminophen (Paracetamol) in Prescription Combination Opioid Products and Subsequent Hospitalizations and Acute Liver Failure
- Moving the Needle to Reduce Acetaminophen (Paracetamol) Hepatotoxicity
- Acetaminophen (Paracetamol) and Acute Liver Failure
In this JAMA author interview, Peter J. Pronovost, MD, PhD, Chief Quality & Clinical Transformation Officer, University Hospitals, Cleveland, and an internationally recognized expert in patient safety, discusses his recent article in JAMA on “Misdiagnosis in the Emergency Department.” A new report from AHRQ underscores the seriousness of this problem. Related Content:
- Misdiagnosis in the Emergency Department
Interview with James Stevermer, MD, MSPH, USPSTF member and coauthor of Serologic Screening for Genital Herpes Infection: US Preventive Services Task Force Reaffirmation Recommendation Statement. Hosted by JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS.
Related Content:
- Serologic Screening for Genital Herpes Infection: US Preventive Services Task Force Reaffirmation Recommendation Statement
- Reducing HSV-2 Morbidity and Mortality>
- Reaffirmed USPSTF Recommendation Against Serologic Screening for Genital Herpes: Empowering Clinicians and Reducing Potential Harm
- Serologic Screening for Genital Herpes: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force
- Screening for Genital Herpes (Patient Page)
Susanna Naggie, MD, vice dean for research at Duke University's School of Medicine, discusses the ACTIV-6 trial of fluvoxamine for outpatient treatment of COVID-19 and outlines the role of platform trials during the pandemic. Hosted by JAMA Deputy Editor and Editorial Director for Equity Preeti Malani, MD, MSJ.
Related Content:
Effect of Fluvoxamine vs Placebo on Time to Sustained Recovery in Outpatients With Mild to Moderate COVID-19
In the wake of new legal challenges to race-conscious admission policies, JAMA Interim Executive Editor Gregory Curfman, MD, discusses racial and ethnic diversity in undergraduate and medical school admission policies with Roy H. Hamilton, MD, MS, from the Perelman School of Medicine, University of Pennsylvania. Related Content:
- Defending Racial and Ethnic Diversity in Undergraduate and Medical School Admission Policies
JAMA Deputy Editor Preeti Malani, MD, MSJ, discusses potential next-generation COVID-19 vaccines with Peter Marks, MD, PhD, director of the Center for Biologics Evaluation and Research at the US Food and Drug Administration. Related Content:
- Urgent Need for Next-Generation COVID-19 Vaccines
In this JAMA author interview, we speak with Robert M. Califf, MD, Commissioner of the FDA, about a remarkable advance in the technology of hearing aids. Dr Califf has done important work to secure the entry of over-the-counter hearing aids into the market, providing a less expensive alternative to traditional hearing aids. In this interview, Dr Califf tells the story of how this technology has finally been made available to the public. Related Content:
- Over-the-counter Hearing Aids: From Research to Policy to Practice
Interview with Chris Zielinski, Visiting Research Fellow and Faculty of Health and Wellbeing at the University of Winchester, UK, James Kigera, Editor-in-Chief, Annals of African Surgery, and James Tumwine, Editor-in-Chief, African Health Sciences, authors of COP27 Climate Change Conference—Urgent Action Needed for Africa and the World. Hosted by JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD.
Related Content:
- COP27 Climate Change Conference—Urgent Action Needed for Africa and the World
- Conflict and Climate Collide to Create an Acute Hunger Crisis for an Unprecedented 345 Million People
- Climate Justice and Health
- Children, Climate Justice, and Lessons From Puerto Rico
Interview with Chris Zielinski, Visiting Research Fellow and Faculty of Health and Wellbeing at the University of Winchester, UK, James Kigera, Editor-in-Chief, Annals of African Surgery, and James Tumwine, Editor-in-Chief, African Health Sciences, authors of COP27 Climate Change Conference—Urgent Action Needed for Africa and the World. Hosted by JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD.
Related Content:
- COP27 Climate Change Conference—Urgent Action Needed for Africa and the World
- Conflict and Climate Collide to Create an Acute Hunger Crisis for an Unprecedented 345 Million People
- Climate Justice and Health
- Children, Climate Justice, and Lessons From Puerto Rico
Interview with Gbenga Ogedegbe, MD, MPH, USPSTF member and coauthor of Screening for Obstructive Sleep Apnea in Adults: US Preventive Services Task Force Recommendation Statement. Hosted by JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS.
Related Content:
- Screening for Obstructive Sleep Apnea in Adults
- Screening for Obstructive Sleep Apnea in Adults
- Screening for Obstructive Sleep Apnea in Adults
- Screening for Obstructive Sleep Apnea
- USPSTF Updates Recommendation for Obstructive Sleep Apnea Screening in Adults
Interview with Gbenga Ogedegbe, MD, MPH, USPSTF member and coauthor of Screening for Obstructive Sleep Apnea in Adults: US Preventive Services Task Force Recommendation Statement. Hosted by JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS.
Related Content:
- Screening for Obstructive Sleep Apnea in Adults
- Screening for Obstructive Sleep Apnea in Adults
- Screening for Obstructive Sleep Apnea in Adults
- Screening for Obstructive Sleep Apnea
- USPSTF Updates Recommendation for Obstructive Sleep Apnea Screening in Adults
Interview with Carol Mangione, MD, MSPH, USPSTF chair and coauthor of Hormone Therapy for the Primary Prevention of Chronic Conditions in Postmenopausal Persons: US Preventive Services Task Force Recommendation Statement. Hosted by JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS.
Related Content:
- Hormone Therapy for the Primary Prevention of Chronic Conditions in Postmenopausal Persons
- Hormone Therapy for the Primary Prevention of Chronic Conditions in Postmenopausal Persons
- Menopausal Hormone Therapy for Prevention of Chronic Conditions
Interview with Martha Kubik, PhD, RN, USPSTF member and coauthor of Screening for Anxiety in Children and Adolescents: US Preventive Services Task Force Recommendation Statement, and Screening for Depression and Suicide Risk in Children and Adolescents: US Preventive Services Task Force Recommendation Statement. Hosted by JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS.
Related Content:
- Screening for Anxiety in Children and Adolescents
- Screening for Anxiety in Children and Adolescents
- Screening for Depression and Suicide Risk in Children and Adolescents
- Screening for Depression and Suicide Risk in Children and Adolescents
- Screening for Anxiety in Children and Adolescents
- Screening for Pediatric Anxiety Disorders
In this JAMA Author Interview, JAMA Interim Executive Editor Greg Curfman, MD, speaks with Mary M. McDermott, MD, professor of medicine at Northwestern University Feinberg School of Medicine, on current therapies for peripheral artery disease and a new clinical trial she directed on the use of telmisartan, an angiotensin receptor blocker, for patients with peripheral artery disease.
Related Content:
Effect of Telmisartan on Walking Performance in Patients With Lower Extremity Peripheral Artery Disease
JAMA Network Open Editor Frederick Rivara, MD, MPH, discusses approaches to reducing firearm violence with several JAMA Viewpoint authors: Sandro Galea, MD, DrPH (Boston University), Elinore J. Kaufman, MD, MSHP (University of Pennsylvania), and Roger A. Mitchell Jr, MD (Howard University). Topics include the state-level response to firearm-related harms, the paucity of data on firearm violence, and the pervasive health effects of firearm violence on neighborhoods and in the carceral system.
Related Content:
- The Epidemiology of Firearm Injuries in the US: The Need for Comprehensive, Real-time, Actionable Data
- Violence and the Carceral State: A Public Health Continuum
- State Firearm Laws and Firearm-Related Mortality and Morbidity
- Examining the Impact of Firearm Safety Laws on Suicides
- Physicians and EMS Who Responded to Mass Shootings Develop Consensus Recommendations for Improving Care
- Approaches to Reducing Firearm Violence
Interview with Katrina E. Donahue, MD, MPH, USPSTF member and coauthor of Screening for Syphilis Infection in Nonpregnant Adolescents and Adults: US Preventive Services Task Force Reaffirmation Recommendation Statement. Hosted by JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS.
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- The Critical Need to Modernize Syphilis Screening
- Screening for Syphilis Infection in Nonpregnant Adolescents and Adults
- Screening for Syphilis Infection in Nonpregnant Adults and Adolescents
- Screening for Syphilis
Interview with Katrina E. Donahue, MD, MPH, USPSTF member and coauthor of Screening for Syphilis Infection in Nonpregnant Adolescents and Adults: US Preventive Services Task Force Reaffirmation Recommendation Statement. Hosted by JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS.
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- The Critical Need to Modernize Syphilis Screening
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JAMA Network Open Editor Frederick Rivara, MD, MPH, discusses approaches to reducing firearm violence with several JAMA Viewpoint authors: Sandro Galea, MD, DrPH (Boston University), Elinore J. Kaufman, MD, MSHP (University of Pennsylvania), and Roger A. Mitchell Jr, MD (Howard University). Topics include the state-level response to firearm-related harms, the paucity of data on firearm violence, and the pervasive health effects of firearm violence on neighborhoods and in the carceral system.
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- The Epidemiology of Firearm Injuries in the US: The Need for Comprehensive, Real-time, Actionable Data
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- State Firearm Laws and Firearm-Related Mortality and Morbidity
- Examining the Impact of Firearm Safety Laws on Suicides
- Physicians and EMS Who Responded to Mass Shootings Develop Consensus Recommendations for Improving Care
- Approaches to Reducing Firearm Violence
CRISPR genome editing is a revolutionary technology that can be used to make highly targeted changes in DNA in living cells. JAMA Associate Editor W. Gregory Feero, MD, PhD, Maine Dartmouth Family Medicine Residency, and Matthew J. Kan, MD, PhD, University of California San Francisco, discuss how CRISPR works and how CRISPR-based technologies are being used in ongoing trials to treat a wide variety of medical conditions.
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Arguably, a clinician’s most important role is providing an accurate and actionable diagnosis for patients. But challenges stand in the way, including tool limitations, inequitable access, and discontinuity of care. In this roundtable Q&A discussion, Urmimala Sarkar, MD, MPH (Zuckerberg San Francisco General Hospital and Trauma Center, UCSF), Jonathan H. Chen, MD, PhD (Stanford Center for Biomedical Informatics Research, Stanford University), and Harvey V. Fineberg, MD, PhD (Gordon and Betty Moore Foundation), discuss issues affecting diagnostic excellence, the emergence of artificial intelligence–driven tools, and ways to make the diagnostic process patient-focused. Hosted by JAMA Editor in Chief Kirsten Bibbins-Domingo, MD, PhD.
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- Decoding Artificial Intelligence to Achieve Diagnostic Excellence
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- Achieving Diagnostic Excellence
CRISPR genome editing is a revolutionary technology that can be used to make highly targeted changes in DNA in living cells. JAMA Associate Editor W. Gregory Feero, MD, PhD, Maine Dartmouth Family Medicine Residency, and Matthew J. Kan, MD, PhD, University of California San Francisco, discuss how CRISPR works and how CRISPR-based technologies are being used in ongoing trials to treat a wide variety of medical conditions.
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- Treatment of Genetic Diseases With CRISPR Genome Editing
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Arguably, a clinician’s most important role is providing an accurate and actionable diagnosis for patients. But challenges stand in the way, including tool limitations, inequitable access, and discontinuity of care. In this roundtable Q&A discussion, Urmimala Sarkar, MD, MPH (Zuckerberg San Francisco General Hospital and Trauma Center, UCSF), Jonathan H. Chen, MD, PhD (Stanford Center for Biomedical Informatics Research, Stanford University), and Harvey V. Fineberg, MD, PhD (Gordon and Betty Moore Foundation), discuss issues affecting diagnostic excellence, the emergence of artificial intelligence–driven tools, and ways to make the diagnostic process patient-focused. Hosted by JAMA Editor in Chief Kirsten Bibbins-Domingo, MD, PhD.
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- Decoding Artificial Intelligence to Achieve Diagnostic Excellence
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Interview with Michael D. Cabana, MD, MA, MPH, USPSTF member and coauthor of Screening for Prediabetes and Type 2 Diabetes in Children and Adolescents: US Preventive Services Task Force Recommendation Statement. Hosted by JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS.
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- Screening for Prediabetes and Type 2 Diabetes in Children and Adolescents
- Screening for Prediabetes and Type 2 Diabetes in Children and Adolescents
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Interview with Michael D. Cabana, MD, MA, MPH, USPSTF member and coauthor of Screening for Prediabetes and Type 2 Diabetes in Children and Adolescents: US Preventive Services Task Force Recommendation Statement. Hosted by JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS.
Related Content:
- Screening for Prediabetes and Type 2 Diabetes in Children and Adolescents
- Screening for Prediabetes and Type 2 Diabetes in Children and Adolescents
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Over a nearly 40-year career at the head of the National Institute of Allergy and Infectious Diseases, Anthony Fauci, MD, has seen a seismic shift in the way that science is communicated to and received by the public. In conversation with JAMA Network Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, Fauci reflects on his career at NIAID, the joys and challenges of advising 7 presidents, and shares his strategies for communicating scientific information in an ever-changing environment.
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- Dr Fauci and the Art of Science Communication
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Over a nearly 40-year career at the head of the National Institute of Allergy and Infectious Diseases, Anthony Fauci, MD, has seen a seismic shift in the way that science is communicated to and received by the public. In conversation with JAMA Network Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, Fauci reflects on his career at NIAID, the joys and challenges of advising 7 presidents, and shares his strategies for communicating scientific information in an ever-changing environment.
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- Dr Fauci and the Art of Science Communication
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Interview with John B. Wong, MD, USPSTF member and coauthor of Statin Use for the Primary Prevention of Cardiovascular Disease in Adults: US Preventive Services Task Force Recommendation Statement. Hosted by JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS.
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- Statin Use for the Primary Prevention of Cardiovascular Disease in Adults
- Statin Use for the Primary Prevention of Cardiovascular Disease in Adults
- Statins for the Prevention of Cardiovascular Disease
- Statin Usage in Primary Prevention—Comparing the USPSTF Recommendations With the AHA/ACC/Multisociety Guidelines
- Statins for Primary Cardiovascular Disease Prevention
- Statins and Primary Atherosclerotic Cardiovascular Disease Prevention—What We Know, Where We Need to Go, and Why Are We Not There Already?
President Biden has signed into law the Inflation Reduction Act containing important provisions related to prescription drug costs. JAMA Health Forum Editor John Z. Ayanian, MD, MPP, and Deputy Editor Melinda B. Buntin, PhD, discuss the effects of these provisions on patients with Aaron S. Kesselheim, MD, JD, MPH, of Harvard Medical School and Brigham and Women’s Hospital.
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- New Reforms to Prescription Drug Pricing in the US
- Estimating Rebates and Other Discounts Received by Medicare Part D
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- Spending by the Centers for Medicare & Medicaid Services Before and After Confirmation of Benefit for Drugs Granted US Food and Drug Administration Accelerated Approval, 2012 to 2017
- Improving Prescription Drug Affordability Through Regulatory Action
In this Author Interview, JAMA Deputy Editor Gregory Curfman, MD, discusses the state of coronary artery bypass surgery in 2022 with E. Magnus Ohman, MD, from Duke University. The conversation emphasizes methods to preserve patency of saphenous vein bypass grafts, the subject of an article in the August 9, 2022, issue of JAMA. Dr Ohman wrote the accompanying Editorial.
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Electronic health records (EHRs) hold great promise to assist clinicians, but current versions are less user-friendly than ideal. JAMA Associate Editor Tracy Lieu, MD, MPH, spoke with Kevin B. Johnson, MD, MS, University of Pennsylvania, and William W. Stead, MD, Vanderbilt University Medical Center, about how to improve EHRs to protect cognitive attention and optimize their potential to provide cognitive support to health care professionals.
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- Making Electronic Health Records Both SAFER and SMARTER
On August 3, 2022, the US Department of Health and Human Services released 2 major reports in response to a presidential memo calling for a whole-of-government response to the SARS-CoV-2 sequelae known as “Long COVID." JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, discusses these new reports and the research and support needed to address this pervasive health concern with HHS Assistant Secretary for Health Rachel Levine, MD. Recorded July 29, 2022.
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- Addressing the Long-term Effects of COVID-19
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Interview with Lori Pbert, PhD, USPSTF member and coauthor of Behavioral Counseling Interventions to Promote a Healthy Diet and Physical Activity for Cardiovascular Disease Prevention in Adults Without Cardiovascular Disease Risk Factors: US Preventive Services Task Force Recommendation Statement. Hosted by JAMA Senior Editor Kristin L. Walter, MD, MS.
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- Behavioral Counseling Interventions to Promote a Healthy Diet and Physical Activity for Cardiovascular Disease Prevention in Adults Without Known Cardiovascular Disease Risk Factors
- Behavioral Counseling Interventions to Promote a Healthy Diet and Physical Activity for Cardiovascular Disease Prevention in Adults Without Cardiovascular Disease Risk Factors
- Behavioral Counseling Interventions to Promote a Healthy Diet and Physical Activity to Prevent CVD in Adults Without Risk Factors
- Implications of the New Recommendation on Behavioral Counseling Interventions to Promote Healthy Eating and Physical Activity
- Improving Behavioral Counseling for Primary Cardiovascular Disease Prevention
- Updated USPSTF Recommendations for Behavioral Counseling Interventions
Exercise limitation is a cardinal manifestation of heart failure with reduced ejection fraction (HFrEF), but it is not consistently improved by any of the current guideline-directed medical therapies. JAMA Deputy Editor Gregory Curfman, MD, discusses whether omecamtiv mecarbil can improve peak exercise capacity in patients with HFrEF with Gregory D. Lewis, MD, from Massachusetts General Hospital, and Mark H. Drazner, MD, MSc, from University of Texas Southwestern Medical Center.
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- Effect of Omecamtiv Mecarbil on Exercise Capacity in Chronic Heart Failure With Reduced Ejection Fraction: The METEORIC-HF Randomized Clinical Trial
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JAMA Associate Editor Preeti Malani, MD, MSJ, discusses the transmission, diagnosis, and treatment of monkeypox and the 2022 outbreak with Jeannette Guarner, MD, and Carlos del Rio, MD, both of the Division of Infectious Diseases at Emory University’s School of Medicine.
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Monkeypox in 2022—What Clinicians Need to Know
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Global Monkeypox Outbreaks Spur Drug Research for the Neglected Disease
Patient safety is a national priority, but adverse events during hospitalization are hard to track and whether progress has been made over the past decade is unknown. JAMA Associate Editor Karen E. Joynt Maddox, MD, MPH, Washington University School of Medicine, discusses recent findings demonstrating decreases in hospital chart-abstracted adverse events and what’s next in patient safety in the wake of COVID-19, with Mark Metersky, MD, University of Connecticut Health Center, and Peter Pronovost, MD, PhD, University Hospitals, Shaker Heights, Ohio.
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Trends in Adverse Event Rates in Hospitalized Patients, 2010-2019
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Improvements in Hospital Adverse Event Rates: Achieving Statistically Significant and Clinically Meaningful Results
In July 2022, Kirsten Bibbins-Domingo, PhD, MD, MAS, took on a new role as the 17th editor in chief of JAMA and the JAMA Network. In conversation with Nobel laureate Harold Varmus, MD, Bibbins-Domingo discusses her research background, approaches to leadership in health care, and the critical role that journals play in communication about public health and science.
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- The Urgency of Now and the Responsibility to Do More—My Commitment for JAMA and the JAMA Network
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- A Conversation With Dr Kirsten Bibbins-Domingo, JAMA’s New Editor in Chief (audio)
Observational data suggest that the risk of certain types of cancer may be increased in individuals with obesity and that this risk may be lower after bariatric surgery. JAMA Deputy Editor Gregory Curfman, MD, explores this in detail with Steven Nissen, MD, an author of a JAMA study on this topic, and Anita Courcoulas, MD, MPH, author of an accompanying editorial.
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Interview with John B Wong, MD, USPSTF member and coauthor of Vitamin, Mineral, and Multivitamin Supplementation to Prevent Cardiovascular Disease and Cancer: US Preventive Services Task Force Recommendation Statement. Hosted by JAMA Deputy Editor Mary M. McDermott, MD.
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Multivitamins and Supplements—Benign Prevention or Potentially Harmful Distraction?
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Patient Information: Vitamins and Minerals to Prevent Cardiovascular Disease and Cancer
Interview with Lisa Rotenstein, MD, MBA, author of A Learning Health System Agenda for Organizational Approaches to Enhancing Occupational Well-being Among Clinicians, and Clyde W. Yancy, MD, author of Resident Physician Wellness Postpandemic: How Does Healing Occur?. Hosted by JAMA Associate Editor Anne Cappola, MD.
Interview with Katrina Erika Donahue, MD, MPH, coauthor of Screening for Primary Open-Angle Glaucoma: US Preventive Services Task Force Recommendation Statement, and Screening for Impaired Visual Acuity in Older Adults: US Preventive Services Task Force Recommendation Statement. Hosted by JAMA Deputy Editor Mary M. McDermott, MD.
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- USPSTF Review: Screening for Glaucoma in Adults
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- Patient Information: Screening for Primary Open-Angle Glaucoma
- Screening for Impaired Visual Acuity in Older Adults
- Patient Information: Screening for Impaired Visual Acuity in Older Adults
- Screening for Glaucoma
As the White House’s COVID-19 Response Coordinator, Ashish Jha, MD, MPH, plays a critical role in the federal government’s continued response to the pandemic. In this Q&A with JAMA Associate Editor Preeti Malani, MD, Jha details current thinking and federal planning around additional boosters, testing trends, and treatment for COVID-19.
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- New White House COVID-19 Leader on What’s Next
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Interview with Katrina E. Donahue, MD, MPH, USPSTF member and coauthor of Screening for Chronic Obstructive Pulmonary Disease: US Preventive Services Task Force Reaffirmation Recommendation Statement. Hosted by JAMA Senior Editor Kristin Walter, MD.
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- USPSTF Review: Screening for Chronic Obstructive Pulmonary Disease
- Screening for Chronic Obstructive Pulmonary Disease: Challenges and Opportunities
- USPSTF Recommendation: Screening for Chronic Obstructive Pulmonary Disease
- Patient Information: Screening for Chronic Obstructive Pulmonary Disease
After serving as commissioner of the US Food and Drug Administration (FDA) under President Obama, Robert M. Califf, MD, recently returned to the role, overseeing a critical federal agency that regulates food, drugs, therapeutics, and medical devices in the US. In a wide-ranging discussion with JAMA Deputy Editor Gregory Curfman, MD, Califf discusses COVID-19 vaccine modifications, the FDA’s approach to evaluating evidence, and efforts to combat health misinformation. Recorded April 26, 2022.
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- “Unfinished Business” Brings Robert Califf, MD, Back for a Second Stint as FDA Commissioner
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Interview with John B. Wong, MD, USPSTF member and coauthor of Aspirin Use for Cardiovascular Disease: US Preventive Services Task Force Recommendation Statement. Hosted by JAMA Deputy Editor Gregory Curfman, MD.
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Aspirin Use to Prevent Cardiovascular Disease: US Preventive Services Task Force Recommendation Statement
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Should Patients Take Aspirin for Primary Cardiovascular Prevention?
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USPSTF Review: Aspirin Use to Prevent Cardiovascular Disease and Colorectal Cancer
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Aspirin Use to Prevent Cardiovascular Disease and Colorectal Cancer: Updated Modeling Study for the US Preventive Services Task Force
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Patient Information: Use of Aspirin to Prevent Cardiovascular Disease
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Whom to Treat for Primary Prevention of Atherosclerotic Cardiovascular Disease
Misinformation about COVID-19 (such as around vaccines, masks, and ineffective drugs) has circulated widely during the pandemic, and much of this misinformation is protected by the Free Speech Clause of the First Amendment. Professor of Surgery and Perioperative Care and Professor of Law William M. Sage, MD, JD, from the University of Texas at Austin, is interviewed in this JAMA podcast.
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Reducing “COVID-19 Misinformation” While Preserving Free Speech
Electrocardiographic markers of atrial myopathy are associated with dementia, but it is unclear whether 2-dimensional echocardiographic––defined LA function and size are associated with dementia. JAMA Senior Editor Philip Greenland, MD, discusses study findings with Wendy Wang, MPH, and Lin Yee Chen, MD, authors of Association of Echocardiographic Measures of Left Atrial Function and Size With Incident Dementia
As the largest public insurance program in the US, Medicare has an outsize influence in how many people in the US access and receive health care. Recently appointed Director of Center for Medicare Meena Seshamani, MD, PhD, joins JAMA Associate Editor Karen Joynt Maddox, MD, for a discussion of equitable, patient-centered approaches to health care delivery, and how her own experiences as a physician have illuminated how she leads the program.
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- Center for Medicare Director Envisions Holistic Approach to Health Care
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Interview with Lori Pbert, PhD, USPSTF member and coauthor of Screening for Eating Disorders in Adolescents and Adults: US Preventive Services Task Force Recommendation Statement
Interview with Gbenga Ogedegbe, MD, MPH, USPSTF member and coauthor of Screening for Atrial Fibrillation: US Preventive Services Task Force Recommendation Statement. Hosted by Gregory Curfman, MD.
Three members of President Biden’s former COVID-19 Advisory Board—Luciana Borio, MD, Ezekiel Emanuel, MD, PhD, and Mike Osterholm, PhD—discuss their recent JAMA Viewpoints, providing their ideas on strategies for public health as COVID-19 transitions from pandemic to endemic. Hosted by JAMA Associate Editor Preeti Malani, MD.
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- A National Strategy for the “New Normal” of Life With COVID
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- Former Biden-Harris Transition Advisors Propose a New National Strategy for COVID-19
- Public Health in an Era of Endemic COVID-19 (video)
Former CDC Executive Secretariat of the Advisory Committee on Immunization Practices Amanda Cohn, MD, joins JAMA Associate Editor Preeti Malani, MD, for the latest on the need for vaccination and boosters, vaccine misinformation, and tackling the pandemic from a global perspective. Recorded January 6, 2022.
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- One Year of COVID-19 Vaccines: A Shot of Hope, a Dose of Reality
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- COVID-19 CDC Update – Early January 2022
Interview with Michael Cabana, MD, USPSTF member and coauthor of Screening and Interventions to Prevent Dental Caries in Children Younger Than 5 Years: US Preventive Services Task Force Recommendation Statement.
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Screening and Interventions to Prevent Dental Caries in Children Younger Than 5 Years
Infectious disease experts Adam Lauring, MD, PhD, and Carlos del Rio, MD, join JAMA Associate Editor Preeti Malani, MD, MSJ, for a discussion of the newly emerged Omicron variant, the potential for a 2021-2022 "twindemic" with flu, and the latest COVID-19 clinical updates. Recorded December 1, 2021.
Related content:
Omicron Has Reached the US—Here’s What Infectious Disease Experts Know About the Variant
COVID-19 Update: Omicron Variant
Phil Fontanarosa, MD, MBA, interim editor in chief of JAMA, interviews Harvey V. Fineberg, MD, PhD, from the Gordon and Betty Moore Foundation, and Abraham Verghese, MD, from Stanford University School of Medicine, about diagnostic excellence and a new series on this topic in JAMA.
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Individuals who experience systemic, structural, institutional, and social barriers within society deserve better and more convenient health care access. This idea should be central when advancing efforts to achieve health equity. JAMA Editorial Board member Raina M. Merchant, MD, speaks with Courtney R. Lyles, PhD, and Urmimala Sarkar, MD, about approaches toward improving digital health equity and with Utibe R. Essien, MD, about enhancing targeted efforts toward realizing pharmacoequity.
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Health care expenses that arise from largely nonclinical functions, such as coding and billing and administration, cost the US health care system almost $1 trillion annually. Michael Chernew, PhD, from Harvard Medical School Department of Health Care Policy, and David Cutler, PhD, from Harvard University Department of Economics, join JAMA Associate Editor Karen Joynt Maddox, MD, MPH, from Washington University School of Medicine to discuss some basic fixes and simplifications that could reduce administrative spending by an estimated $265 billion.
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- Waste in the US Health Care System: Estimated Costs and Potential for Savings
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- Administrative Simplification and the Potential for Saving a Quarter-Trillion Dollars in Health Care
- Economic Incentives for Administrative Simplification
- Waste in the US Health Care System
- Waste in the US Health Care System
Interview with Jason A. Abbott, and Fiona G Li, authors of Effect of Fractional Carbon Dioxide Laser vs Sham Treatment on Symptom Severity in Women With Postmenopausal Vaginal Symptoms: A Randomized Clinical Trial
Death rattle, defined as noisy breathing caused by the presence of mucus in the respiratory tract, is common among dying patients. Harriette van Esch, MD, from the Erasmus Medical Center, the Netherlands, and Jared R. Lowe, MD, from the University of North Carolina, join JAMA Associate Editor Ethan Basch, MD, to discuss evidence about use of prophylactic scopolamine butylbromide to reduce the death rattle.
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Effect of Prophylactic Subcutaneous Scopolamine Butylbromide on Death Rattle
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Preventing Death Rattle With Prophylactic Subcutaneous Scopolamine Butylbromide
Interview with Aaron B. Caughey, MD, USPSTF member and coauthor of Aspirin Use to Prevent Preeclampsia and Related Morbidity and Mortality: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force
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- Low-Dose Aspirin for the Prevention of Preeclampsia
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Canadian law gives the country’s individual provinces and territories primary responsibility for coronavirus containment and mitigation. JAMA Associate Editor Preeti Malani, MD, MSJ, from the University of Michigan and Allan S. Detsky, MD, PhD, from the University of Toronto, Ontario, Canada, discuss the national pandemic experience, including public health responses to infection and vaccine allocation, from fall 2020 through summer 2021.
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- COVID-19 in Canada: Experience and Response to Waves 2 and 3
Interview with Martha Kubik, PhD, RN, USPSTF member and coauthor of Screening for Chlamydia and Gonorrhea: US Preventive Services Task Force Recommendation Statement
While health disparities have gained growing attention in recent years, much work is still needed, as inequities continue to have a direct and measurable negative influence on patients in historically disadvantaged communities. David Satcher, MD, PhD, Francisco Cigarroa, MD, and Howard Koh, MD, MPH, join moderator Ebony Boulware, MD, MPH, to discuss the vital importance of the visibility of all races and ethnicities in research, medical schools, and health care. They propose potential solutions, including the recruitment of and support for more physicians who look like their patients, who care enough, know enough, have the courage to make a difference, and who will persevere until changes are made.
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- Healing and Health Equity for Asian American, Native Hawaiian, and Pacific Islander Populations
- Uplifting the Latino Population From Obscurity to the Forefront of Health Care
- Does Race Interfere With the Doctor-Patient Relationship? (published 1973)
- Race and the Patient-Physician Relationship in 2021
Noninvasive ventilation (NIV) may help COVID-19 patients in respiratory failure avoid invasive mechanical ventilation but may also lead to delays in intubation with potential for worse clinical outcomes.
Domenico L. Grieco, MD, of Fondazione Policlinico Agostino Gemelli IRCCS in Rome, Jesse B. Hall, MD, of the University of Chicago, and Laveena Munshi, MD, MSc, of Sinai Health System/University Health Network of the University of Toronto join JAMA's live Q&A series to discuss helmet NIV, high-flow nasal oxygen, and other NIV modalities in the management of hypoxic coronavirus patients. Recorded March 25, 2021.
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Effect of Helmet Noninvasive Ventilation vs High-Flow Nasal Oxygen on Days Free of Respiratory Support in Patients With COVID-19 and Moderate to Severe Hypoxemic Respiratory Failure
Respiratory Support During the COVID-19 Pandemic: Is It Time to Consider Using a Helmet?
Noninvasive Ventilation of COVID-19 Patients
Interview with Kimberly Maxfield, PhD, author of Precision Dosing—A Clinical and Public Health Imperative
Interview with Chien-Wen W. Tseng, MD, USPSTF member and coauthor of USPSTF Recommendation: Screening for Hearing Loss in Older Adults
Coronavirus trends, variants, vaccines, treatment, and more. JAMA Associate Editor Preeti Malani, MD, MSJ, also from the University of Michigan, and Emory University School of Medicine's Carlos del Rio, MD, return to JAMA's Q&A series to discuss the latest in COVID-19 medicine and public health. Recorded March 15, 2021.
Related Content:
- COVID-19 in 2021—Continuing Uncertainty
- Coronavirus Update With Carlos del Rio and Preeti Malani
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Lisa A. Cooper, MD, MPH, of Johns Hopkins University School of Medicine; Clyde W. Yancy, MD, MSc, of Northwestern University, and David R. Williams, PhD, MPH, of Harvard T.H. Chan School of Public Health, join JAMA Editor in Chief Howard Bauchner, MD, to discuss racism and structural racism in health care and medicine. Recorded March 16, 2021.
Interview with Thomas R. Frieden, MD, MPH, author of National Initiatives to Prevent Myocardial Infarction and Stroke
Interview with Michael J. Barry, MD, author of USPSTF Recommendation—Screening for Lung Cancer
Genetic variants of the SARS-CoV-2 virus are emerging but so far do not seem to have caused breakthrough infections in people with previous infection or in those who have been vaccinated. John P. Moore, PhD, of Weill Medical College of Cornell University in New York, joins JAMA's Q&A series for an update on the latest variants and what you need to know. Recorded March 4, 2021.
Related Article:
Approaches for Optimal Use of Different COVID-19 Vaccines
Interview with Christopher J.L. Murray, MD, DPhil, author of The Potential Future of the COVID-19 Pandemic: Will SARS-CoV-2 Become a Recurrent Seasonal Infection?
Interview with James C. Robinson, PhD, author of Funding of Pharmaceutical Innovation During and After the COVID-19 Pandemic
Nancy E. Messonnier, MD is director of the National Center for Immunization and Respiratory Diseases (NCIRD) at the Centers for Disease Control and Prevention (CDC) and leads the CDC’s efforts on COVID-19 vaccination. She joins JAMA's Q&A series to discuss the agency's response to emerging coronavirus variants, the FDA advisory hearings on the new Johnson & Johnson vaccine, and other agency activities and priorities related to COVID-19 control. Recorded February 26, 2021.
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- Genetic Variants of SARS-CoV-2—What Do They Mean?
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- SARS-CoV-2 Vaccines and the Growing Threat of Viral Variants
- Experts Discuss COVID-19—Vaccine Doses, Virus Variants, and More
- Emergence of a Novel SARS-CoV-2 Variant in Southern California
- SARS-CoV-2 Variants of Concern in the United States
- Pregnant People Getting Mixed Messages About COVID-19 Vaccines
- The Johnson & Johnson Vaccine for COVID-19
- SARS-CoV-2 Viral Variants—Tackling a Moving Target
- Vaccine Distribution—Equity Left Behind?
- Taking Vaccine to Where the Virus Is—Equity and Effectiveness in Coronavirus Vaccinations?
Interview with Richard Saitz, MD, author of Removing One Barrier to Opioid Use Disorder Treatment: Is It Enough and with Yngvild Olsen, MD, author of Overcoming Barriers to Treatment of Opioid Use Disorder
Interview with Ik-Kyung Jang, MD, PhD, author of New Insights Into Plaque Erosion as a Mechanism of Acute Coronary Syndromes
CDC Director Rochelle P. Walensky, MD, MPH, returns to JAMA's Q&A series to discuss the agency's response to emerging SARS-CoV-2 variants, implications for the planned vaccine mobilization strategy, the upcoming Johnson & Johnson vaccine FDA advisory hearings, strategies for reopening K-12 schools, and other agency activities and priorities related to COVID-19 control. Recorded February 17, 2021.
Related Article(s):
- Coronavirus Update With CDC Director Rochelle Walensky - February 17, 2021
- SARS-CoV-2 Variants of Concern in the United States—Challenges and Opportunities
- SARS-CoV-2 Viral Variants—Tackling a Moving Target
Paul A. Offit, MD, of The Children's Hospital of Philadelphia returns to JAMA's Q&A series to provide an update on the emergence of COVID-19 variants and their implications for vaccine development, including the Johnson & Johnson vaccine, scheduled for a US Food and Drug Administration VRBPAC hearing on February 26, 2021. Recorded February 11, 2021.
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As US vaccine distribution expands to include younger healthier populations, questions about vaccine safety in women of childbearing age have become more urgent. University of Texas Southwestern Medical Center's Catherine Y. Spong, MD, and Emory University School of Medicine's Denise J. Jamieson, MD, MPH, both eminent obstetrician/gynecologists, join JAMA's Q&A series to discuss the safety of the Pfizer-BioNTech and Moderna vaccines in pregnant and nursing mothers, and in individuals trying to get pregnant. Recorded February 8, 2021.
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- COVID-19 Vaccination in Pregnant and Lactating Women
- Involving Pregnant Individuals in Clinical Research on COVID-19 Vaccines
Interview with Donald Berwick, MD, author of The Triple Aim Applied to Correctional Health Systems
2021 has brought news of emerging SARS-CoV-2 genetic variants that increase transmissibility. Will they diminish vaccine efficacy and lead us to lose pandemic control? University of Michigan's Adam Lauring, MD, PhD, a molecular virologist who uses evolutionary theory to study viral transmission and pathogenesis, joins JAMA's Q&A series to explain the variants and what they mean for public health. Recorded February 4, 2021.
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Genetic Variants of SARS-CoV-2—What Do They Mean?
NIAID Director Anthony S. Fauci, MD, returns to JAMA's Q&A series to discuss
- Shifts in the US pandemic response under the Biden administration
- Emerging genetic variants and implications for vaccine efficacy
- Prospects for new vaccine approvals and more.
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Preventing the Spread of SARS-CoV-2 With Masks and Other “Low-tech” Interventions
Interview with Philip A. Pizzo, MD, author of When Physicians Engage in Practices That Threaten the Nation’s Health
Interview with Peter Pronovost, MD, PhD, author of Ensuring Quality in the Era of Virtual Care and Abraham Verghese, MD, author of Virtual Care and Real Connection in the Era of COVID-19
Interview with Michael J. Barry, MD, USPSTF member and coauthor of USPSTF Recommendation: Carotid Artery Stenosis
Peter Piot, MD, PhD, director of The London School of Hygiene and Tropical Medicine, is a legend in global health, having been involved in identification of HIV and Ebola virus in Africa. He was founding executive director of UNAIDS and Under Secretary-General of the United Nations from 1995 to 2008. He joins JAMA's Q&A series to discuss the global public health response to COVID-19 past, present, and future. Recorded January 28, 2021.
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The Challenges Ahead With Monoclonal Antibodies
Interview with Frederick P. Rivara, MD, author of Three Interventions to Address the Other Pandemic—Firearm Injury and Death
President Biden has released a health care plan that proposes reducing the age of eligibility for Medicare to 60 years and introducing a public option. Larry Levitt, MPP, Executive Vice President for Health Policy at the Kaiser Family Foundation, JAMA Associate Editor Karen Joynt Maddox, MD, MPH, Co-Director of the Center for Health Economics and Policy (CHEP) at Washington University School of Medicine, and Lawrence O. Gostin, JD, from the O’Neill Institute for National and Global Health Law at Georgetown University discuss prospects for health care reform under the new administration. Recorded January 21, 2021.
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Moving Patient Care Forward in the Biden Era
Interview with John P A Ioannidis, MD, DSC, author of Recalibrating the Use of Race in Medical Research
To get more vaccine to more people more efficiently, UCSF School of Medicine's Robert M. Wachter, MD, recently urged giving a single dose now and deferring the second dose until more vaccine is available. Paul A. Offit, MD, of The Children's Hospital of Philadelphia, disagrees. The two discuss the pros and the cons of the plan and alternative responses to road bumps in the US vaccine rollout, on JAMA's live Q&A series. Recorded January 19, 2021.
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Incoming Centers for Disease Control and Prevention (CDC) Director Rochelle P. Walensky, MD, MPH, returns to JAMA's Q&A series to discuss her vision and priorities for the agency and changes in its pandemic response strategies, when she takes the reins on January 20. Recorded January 19, 2021.
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All-Cause Excess Mortality and COVID-19–Related Mortality Among US Adults Aged 25-44 Years, March-July 2020
Interview with Michael Silverstein, MD, MPH, USPSTF member and coauthor of USPSTF Recommendation: Tobacco Cessation in Adults
Interview with Raina M. Merchant, MD, author of Public Health Messaging in an Era of Social Media
Intravenous thrombolysis (IVT) and endovascular thrombectomy (EVT) both improve outcomes for patients with acute ischemic stroke. Jeffrey L. Saver, MD, director of UCLA’s Comprehensive Stroke and Vascular Neurology Program and a JAMA Associate Editor, discusses 2 randomized trials comparing outcomes for stroke patients treated with IVT prior to EVT vs EVT alone.
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The COVID-19 pandemic has prompted scientists to use adaptive research designs to evaluate potential treatments simultaneously and efficiently, increasing the likelihood that patients will receive treatments most likely to be effective for them. Lennie Derde, MD, of University Medical Center Utrecht in the Netherlands and JAMA Associate Editor Christopher W. Seymour, MD, of University of Pittsburgh Medical Center join JAMA's Q&A series to discuss the latest in critical care management of COVID-19 patients and emerging treatment strategies and therapies. Recorded January 13, 2021.
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Sensible Medicine-Optimizing the Trade-off Between Learning and Doing in a Pandemic
Arnold S. Monto, MD, chaired the US Food and Drug Administration's Vaccines and Related Biological Products Advisory Committee (VRBPAC) meetings in December that led to Emergency Use Authorization (EUA) of the Pfizer/BioNTech and Moderna vaccines. He joins JAMA's Q&A series from the University of Michigan School of Public Health to discuss experience to date with the 2 products and what's next in vaccine development. Recorded January 11, 2021.
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Experts Discuss COVID-19: Vaccine Allocation, Placebo Groups, and More
Increasing the number of physicians who are Black, Hispanic/Latinx, and Indigenous benefits everyone in the US, but it cannot be the sole responsibility of historically Black colleges and universities (HBCUs). Valerie Montgomery Rice, MD, president and dean of Morehouse School of Medicine (MSM), and Clyde W. Yancy, MD, of Northwestern Medicine, join JAMA Editor in Chief Howard Bauchner, MD, to discuss options for developing training pipelines of underrepresented minority health science students, and how academic medicine can make racial justice a part of its work and mission. Recorded January 5, 2021.
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The National Academy of Medicine's 2000 report "To Err Is Human" launched the health care quality movement in the US. Victor Dzau, MD, president of the National Academy of Medicine, and Don Berwick, MD, MPP, from the Institute for Healthcare Improvement, discuss progress to date in advancing quality and prospects for improving outcomes and reducing harms, errors, and cost in the next 20 years. Recorded December 22, 2020.
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Interview with Geoffrey S. Ginsburg, MD, PhD, author of Digital Health—The Need to Assess Benefits, Risks, and Value
With coronavirus vaccines now available, what are the timeline and prospects for "herd immunity" and return to a new normal? Marc Lipsitch, DPhil, of Harvard T.H. Chan School of Public Health returns to JAMA's Q&A series with Paul D. Biddinger, MD, director of Massachusetts General Hospital's Center for Disaster Medicine, to discuss. Recorded December 17, 2020.
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- Herd Immunity and Implications for SARS-CoV-2 Control
- Herd Immunity as a Coronavirus Pandemic Strategy
Peter W. Marks, MD, PhD, and Stephen M. Hahn, MD, return to JAMA's Q&A series to discuss the Pfizer/BioNTech and Moderna vaccines: the data, the weekend's EUA designation (Pfizer/BioNTech), and the process for future full licensure and postmarketing safety surveillance.
Dr Marks directs the US FDA's Center for Biologics Evaluation and Research (CBER).
Dr Hahn is commissioner of the US Food and Drug Administration.
Recorded December 14, 2020.
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Behaviorally Informed Strategies for a National COVID-19 Vaccine Promotion Program
Interview with David W. Baker, MD, MPH, author of Trust in Health Care in the Time of COVID-19
Anthony S. Fauci, MD, returns to JAMA's Q&A series to discuss the Pfizer/BioNTech and Moderna vaccines: the public data, deliberations at Thursday's FDA Advisory Committee meeting, and prospects for an agency Emergency Use Authorization designation, licensure, and rollout. Recorded December 11, 2020.
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Coronavirus Infections—More Than Just the Common Cold
Interview with Chyke A. Doubeni, MD, MPH, USPSTF member and coauthor of USPSTF Recommendation: Screening for Hepatitis B Virus Infection in Adolescents and Adults
The COVID Tracking Project, launched by The Atlantic, collects and publishes data required to understand the COVID-19 outbreak in the US, including data on race and ethnicity needed to understand health inequities in the outbreak.
Atlantic Monthly journalists Alexis C. Madrigal and Erin Kissane join JAMA's Q&A series to describe the project and their experience developing a database for fact-based health reporting on the pandemic.
Recorded December 10, 2020.
The National Asthma Education and Prevention Program (NAEPP) of the NIH has updated its guideline recommendations for diagnosis and treatment of asthma patients. Michelle M. Cloutier, MD, from UConn Health, Stephanie Lovinsky-Desir, MD, of Columbia University Irving Medical Center, and JAMA Associate Editor George O'Connor, MD, MS, from Boston Medical Center join JAMA's Q&A series to discuss what's new, including revised advice about
• Use of intermittent inhaled corticosteroids (ICSs)
• Use of add-on long-acting muscarinic antagonists (LAMAs)
• Use of fractional exhaled nitric oxide (FeNO) measurement as a diagnostic biomarker
• Monitoring response to therapy
• Indoor allergen mitigation strategies
• Safety and efficacy of subcutaneous and sublingual immunotherapy
• Use of bronchial thermoplasty
Recorded December 8, 2020
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With the Pfizer and Moderna coronavirus vaccines reportedly under review at the US FDA for Emergency Use Authorization (EUA), Paul A. Offit, MD, of the Children's Hospital of Philadelphia, returns to JAMA's Q&A series to provide an update on what to expect, prospects for vaccine rollout and distribution in the coming months, and ongoing safety surveillance. Recorded December 2, 2020.
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Interview with Lawrence O. Gostin, JD, author of Health Policy in the Supreme Court and a New Conservative Majority
Yale Sterling Professor Nicholas A. Christakis, MD, PhD, MPH, returns to JAMA's Q&A series to discuss the surge in US cases and other recent pandemic developments. Dr Christakis is author of the recently published book "Apollo's Arrow: The Profound and Enduring Impact of Coronavirus on the Way We Live." Recorded November 23, 2020.
Interview with Martha Y. Kubik, PhD, RN, USPSTF member and coauthor of Healthy Diet and Physical Activity for Cardiovascular Disease Prevention in Adults With Cardiovascular Risk Factors
In the midst of rising COVID-19 case rates globally, Derek C. Angus, MD, MPH, and Rochelle P. Walensky, MD, MPH, return to JAMA's Q&A series to update viewers on developments in the pandemic and the critical care management of COVID-19 patients. Dr Angus is Chief Health Care Innovation Officer at the University of Pittsburgh Medical Center, professor and chair of Critical Care Medicine, and a senior JAMA editor. Dr Walensky is Chief of Infectious Diseases at Massachusetts General Hospital and a professor at Harvard Medical School. Recorded November 19, 2020.
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Interview with Ipsit V. Vahia, MD, author of Older Adults and the Mental Health Effects of COVID-19
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Older Adults and the Mental Health Effects of COVID-19
Interview with Eli Y. Adashi, MD, MS, author of Heritable Human Genome Editing: The International Commission Report
Would letting coronavirus infect the broad US and global population be a safe and effective means of ending the COVID-19 pandemic? Jay Bhattacharya, MD, PhD, of Stanford University's Center for Primary Care and Outcomes Research is a signatory of the "Great Barrington Declaration," which proposes to "allow those at minimal risk of death to live their lives normally to build up immunity to the virus through natural infection, while better protecting those who are at highest risk." Marc Lipsitch, PhD, of the Harvard T.H. Chan School of Public Health, a signatory of the "John Snow Memorandum," which refutes the argument, responds.
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Ngozi O. Ezike, MD, director of the Illinois Department of Public Health, discusses state and regional management of the COVID-19 pandemic. Recorded November 9, 2020.
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Interview with Michael Silverstein, MD, USPSTF member and coauthor of Screening for Hypertension in Children and Adolescents
Interview with Carlos del Rio, MD, author of Long-term Health Consequences of COVID-19
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Anthony S. Fauci, MD, returns to JAMA's Q&A series to discuss the latest developments in the COVID-19 pandemic, including the continued importance of nonpharmaceutical interventions (masking, handwashing, physical distancing) for managing rising case numbers in the US and globally. Recorded October 28, 2020.
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Paul A. Offit, MD, of the Children's Hospital of Philadelphia, returns to JAMA's Q&A series to provide an update on progress in COVID-19 vaccine development. Recorded October 27, 2020.
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Interview with Kathryn A. Phillips, PhD, author of Expanding Use of Clinical Genome Sequencing and the Need for More Data on Implementation
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Rochelle P. Walensky, MD, MPH, of Harvard Medical School and Massachusetts General Hospital returns to JAMA's COVID-19 Q&A to provide an update on developments in the pandemic. She is a signatory of the recent John Snow Memorandum emphasizing the importance of public health interventions to manage the spread of COVID-19. Recorded October 22, 2020.
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Preventing the Spread of SARS-CoV-2 With Masks and Other “Low-tech” Interventions
The costs of the coronavirus pandemic are unprecedented in their dimensions:
David M. Cutler, PhD, of Harvard University discusses financial costs: the $16 trillion virus.
Lisa Cooper, MD, MPH, of Johns Hopkins University discusses the costs to communities of color in excess deaths and bereavement.
Charles R. Marmar, MD, of NYU Grossman School of Medicine discusses the mental health costs. Recorded October 20, 2020.
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Andy Slavitt, MBA, discusses recent developments in the COVID-19 pandemic and the US response. Slavitt is former Acting CMS Administrator in the Obama administration, board director at the United States of Care in Washington, DC, and a Distinguished Health Policy Fellow at the Leonard Davis Institute of Health Economics at the University of Pennsylvania in Philadelphia. Recorded October 16, 2020.
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The COVID-19 Pandemic Underscores the Need to Address Structural Challenges of the US Health Care System
The National Academy of Medicine has recommended that racial minority populations receive priority for vaccination because they have been hard hit by the pandemic and are "worse off" socioeconomically. US law is inconsistent on whether race/ethnicity can be an explicit criterion for achieving equity and diversity. Lawrence O. Gostin, JD, of Georgetown University and Michelle A. Williams, ScD, of Harvard T.H. Chan School of Public Health discuss ways to achieve the public health objective of protecting vulnerable communities while adhering to law and ethics. Recorded October 14, 2020.
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Is It Lawful and Ethical to Prioritize Racial Minorities for COVID-19 Vaccines?
Interview with Christopher W. Seymour, MD, MSc, author of Sensible Medicine—Balancing Intervention and Inaction During the COVID-19 Pandemic
The US Surgeon General’s office has released a report emphasizing the importance of making hypertension control a national public health priority. Vice Admiral Jerome Adams, MD, MPH, the 20th US Surgeon General, discusses the report's background and recommendations. Recorded October 7, 2020.
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A National Commitment to Improve the Care of Patients With Hypertension in the US
Peter Marks, MD, PhD, directs the US FDA's Center for Biologics Evaluation and Research (CBER) and will "call the balls and strikes" on any COVID-19 vaccine, according to FDA Commissioner Stephen Hahn. He joins JAMA Editor Howard Bauchner, MD, for an update on vaccine progress to date and prospects for pre-election political interference in the FDA approval process. Recorded October 5, 2020.
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On October 2 the US National Academies of Science, Engineering, and Medicine issued its consensus Framework for Equitable Allocation of a COVID-19 Vaccine. William H. Foege, MD, MPH, emeritus distinguished professor of International Health at the Rollins School of Public Health at Emory University, cochaired the committee that authored the report and discusses its recommendations. Recorded October 2, 2020.
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Fairly Prioritizing Groups for Access to COVID-19 Vaccines
Interview with William H. Shrank, MD, author of De-adopting Low-Value Care: Evidence, Eminence, and Economics
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Anthony S. Fauci, MD, returns to JAMA's Q&A series to discuss the latest developments in the COVID-19 pandemic. Recorded September 25, 2020.
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Reassuring the Public and Clinical Community About the Scientific Review and Approval of a COVID-19 Vaccine
Michael T. Osterholm, PhD, MPH, returns to JAMA's Coronavirus Q&A series to discuss the latest developments in the COVID-19 pandemic. He is director of the Center for Infectious Disease Research and Policy (CIDRAP) at University of Minnesota and a veteran of pandemic planning. Recorded September 23, 2020.
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Fairly Prioritizing Groups for Access to COVID-19 Vaccines
Hydroxychloroquine and convalescent plasma approvals by the FDA under Emergency Use Authorization (EUA) protocols have raised concerns the agency is under withering political pressure to fast-track a COVID-19 vaccine before it is proven safe and effective. Joshua Sharfstein, MD, Johns Hopkins Bloomberg School of Public Health, and JAMA Associate Editor Preeti Malani, MD, University of Michigan, discuss implications for public health and policy responses to ensure vaccine safety. Recorded September 18, 2020.
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Reassuring the Public and Clinical Community About the Scientific Review and Approval of a COVID-19 Vaccine
Interview with Aaron S. Kesselheim, MD, author of Regulatory Decision-making on COVID-19 Vaccines During a Public Health Emergency
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Regulatory Decision-making on COVID-19 Vaccines During a Public Health Emergency
New data show unfavorable US trends in hypertension and obesity, with communities of color doing worse. National Institute of Diabetes and Digestive and Kidney Diseases Director Griffin P. Rodgers, MD, and National Heart, Lung, and Blood Institute Director Gary H. Gibbons, MD, discuss the implications for COVID-19 outcomes and public health. Recorded September 10, 2020.
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Trends in Blood Pressure Control Among US Adults With Hypertension, 1999-2000 to 2017-2018
Interview with Atul J Butte, MD, PhD, author of The Case for Algorithmic Stewardship for Artificial Intelligence and Machine Learning Technologies
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Interview with Deborah Korenstein, MD, and Daniel J. Morgan, MD, author of Improving Physician Communication About Treatment Decisions: Reconsideration of “Risks vs Benefits”
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A conversation with Jonathan A. C. Sterne, MA, MSc, PhD, of the University of Bristol, Todd W. Rice, MD, MSc, of Vanderbilt University, and Janet V. Diaz, MD, of the World Health Organization (WHO) on the latest research supporting the use of hydrocortisone and dexamethasone for treatment of COVID-19 ARDS. Recorded September 2, 2020.
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Effect of Hydrocortisone on 21-Day Mortality or Respiratory Support Among Critically Ill Patients With COVID-19
Paul A. Offit, MD, of the Children's Hospital of Philadelphia provides an update on COVID-19 vaccine development. Recorded August 24, 2020.
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Interview with Catherine Lucey, MD, FACP, author of The Transformational Effects of COVID-19 on Medical Education
CDC Director Robert Redfield, MD, discusses recent developments in the COVID-19 pandemic and US response, including prospects for dual outbreaks of COVID-19 and influenza in the fall and winter.
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Addressing Influenza Vaccination Disparities During the COVID-19 Pandemic
Ezekiel Emanuel, MD, PhD, of the University of Pennsylvania's Perelman School of Medicine, Department of Medical Ethics and Health Policy, discusses recent developments in the COVID-19 pandemic. Recorded August 19, 2020.
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Interview with Melissa A Simon, MD, USPSTF member and coauthor of Behavioral Counseling Interventions to Prevent Sexually Transmitted Infections: US Preventive Services Task Force Recommendation Statement
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Behavioral Counseling Interventions to Prevent Sexually Transmitted Infections
Interview with Matcheri S. Keshavan, MD, author of The Convergence of Neurology and Psychiatry: The Importance of Cross-Disciplinary Education
Soumya Swaminathan, MD, DNB, chief scientist at the World Health Organization (WHO), discusses the global coronavirus pandemic and the WHO response. Recorded August 5, 2020.
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COVID-19 Reveals Urgent Need to Strengthen the World Health Organization
Anthony Fauci, MD, White House Coronavirus Task Force member and director of the National Institute of Allergy and Infectious Diseases, discusses latest developments in the COVID-19 pandemic. Recorded August 3, 2020.
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US Food and Drug Administration (FDA) Commissioner Stephen Hahn, MD, discusses the agency's role in responding to the COVID-19 pandemic. Recorded July 30, 2020.
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The World Brain Death Project was undertaken to establish minimum standards for diagnosing brain death/death by neurologic criteria (BD/DNC) in children and adults across a broad range of settings and clinical circumstances. In this Q&A, senior authors of the 2020 report join an editorialist and bioethicist to discuss the project. Featuring interviews with Gene Sung, MD, of the University of Southern California; Ariane Lewis, MD, of NYU Langone Medical Center; Robert Tasker, MD, of the University of Cambridge; and Robert D. Truog, MD, of Harvard University.
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Interview with Jan M. Friedman, MD, PhD, author of Exome Sequencing and Clinical Diagnosis
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Katherine Auger, MD, MSc, of Cincinnati Children's Hospital and Julie Donohue, PhD, of University of Pittsburgh's Graduate School of Public Health discuss K-12 school reopening policy options and the way forward for the 2020-21 school year. Recorded July 29, 2020.
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Ford Foundation President Darren Walker discusses the role of philanthropic organizations in responding to the COVID-19 pandemic and to health inequities. Recorded July 28, 2020.
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Interview with Neil R. Powe, MD, author of Black Kidney Function Matters: Use or Misuse of Race?
Interview with Adrian F. Hernandez, MD, author of National Hospital Quality Rankings: Improving the Value of Information in Hospital Rating Systems
Eric Topol, MD, Scripps Research EVP and omnivorous science health care and tech commentator, discusses the evolving COVID-19 pandemic. Recorded July 23, 2020.
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CDC Director Robert R. Redfield, MD, discusses the ongoing COVID-19 pandemic and the agency’s latest recommendations. Recorded July 14, 2020.
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Interview with Michelle D. Carlson, MD, author of Assessing Quantitative Comparisons of Health and Social Care Between Countries
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Kalpalatha K. Guntupalli, MD, of Baylor College of Medicine discusses the surge and ICU management of COVID-19 patients in Houston, Texas. Recorded July 10, 2020.
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Presenting Characteristics, Comorbidities, and Outcomes Among 5700 Patients Hospitalized With COVID-19 in the New York City Area
Infectious disease physician Rochelle P. Walensky, MD, MPH, of Harvard University discusses the ongoing COVID-19 pandemic. Recorded July 8, 2020.
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Airborne Spread of SARS-CoV-2 and a Potential Role for Air Disinfection
Anthony Fauci, MD, White House Coronavirus Task Force member and Director of the National Institutes of Allergy and Infectious Diseases, discusses latest developments in the COVID-19 pandemic. Recorded on July 2, 2020.
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Interview with Benjamin D. Horne, PhD, author of Limited Evidence for the Health Effects and Safety of Intermittent Fasting Among Patients With Type 2 Diabetes
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Anne Schuchat, MD, Principal Deputy Director of the Centers for Disease Control and Prevention (CDC), discusses latest developments in the COVID-19 pandemic. Recorded on June 29, 2020.
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Intensivists Flavia R. Machado, MD, PhD, of the Federal University of São Paulo, and Jorge Salluh, MD, PhD, of the D’OR Institute for Research and Education in Rio de Janeiro, discuss the surge of COVID-19 cases and ICU management of patients in Brazil. Recorded June 26, 2020.
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Latin America and Its Global Partners Toil to Procure Medical Supplies as COVID-19 Pushes the Region to Its Limit
Michael Osterholm, PhD, MPH, of UMN’s Center for Infectious Disease Research and Policy, discusses the summer rise in US COVID-19 cases, prospects for school reopening, a "second wave" in the fall, and more. Recorded June 24, 2020.
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Vulnerability to Pandemic Flu Could Be Greater Today Than a Century Ago
Infectious disease and global health expert Carlos del Rio, MD, of Emory University provides an update on the status of the #COVID19 pandemic in summer 2020, prospects for effective treatment and prevention, communicating the ongoing risk to the public, and more. Recorded June 15, 2020.
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Interview with Howard K. Koh, MD, author of Sustainability, Business, and Health
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Interview with William H. Shrank, MD, author of Hospice Carve-In—Aligning Benefits With Patient and Family Needs
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COVID-19 critical care update with Maurizio Cecconi, MD, of Humanitas University in Milan, Italy, and JAMA Associate Editor Derek C. Angus, MD, MPH, of the University of Pittsburgh. Recorded June 8, 2020.
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Interview with Karina W. Davidson, PhD, USPSTF member and coauthor of Screening for Unhealthy Drug Use: US Preventive Services Task Force Recommendation Statement
Interview with Anthony L. Komaroff, MD, author of Can Infections Cause Alzheimer Disease?
Joshua M. Sharfstein, MD, and Christopher Morphew, PhD, of Johns Hopkins University discuss options for opening primary, middle, and high schools in fall 2020. Recorded June 3, 2020.
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NIAID Director Anthony Fauci, MD, discusses recent developments in the global COVID-19 pandemic with JAMA Editor in Chief Howard Bauchner, MD. Recorded June 2, 2020.
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Paul Offit, MD, of the Children's Hospital of Philadelphia, discusses principles and progress to date in COVID-19 vaccine development. Recorded June 1, 2020.
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Adverse Consequences of Rushing a SARS-CoV-2 Vaccine: Implications for Public Trust
Paul Starr, PhD, Professor of Sociology and Public Affairs at Princeton University, discusses policy options for achieving a new normal in the COVID-19 pandemic. Recorded Thursday, May 28, 2020.
Related Article: Using Controlled Trials to Resolve Key Unknowns About Policy During the COVID-19 Pandemic
Interview with Zirui Song, M.D., Ph.D., author of Potential Implications of Lowering the Medicare Eligibility Age to 60
Interview with Michael Silverstein, MD, MPH, USPSTF member and coauthor of Primary Care–Based Interventions to Prevent Illicit Drug Use in Children, Adolescents, and Young Adults: US Preventive Services Task Force Recommendation Statement
Interview with Humayun J. Chaudhry, DO, author of The USMLE Step 1 Decision: An Opportunity for Medical Education and Training
US National Institutes of Health (NIH) Director Francis S. Collins, MD, PhD, discusses the agency's new initiative to collaborate with other agencies and industry to accelerate development and testing of COVID-19 treatments and vaccines. Recorded May 19, 2020.
Related: Accelerating COVID-19 Therapeutic Interventions and Vaccines (ACTIV): An Unprecedented Partnership for Unprecedented Times
Ezekiel Emanuel, MD, PhD, of the Perelman School of Medicine's Department of Medical Ethics and Health Policy, discusses the use of immunity licensing (immunity passports) as a means to restore public travel, activity, and the economy following the first wave of the COVID-19 pandemic. Recorded May 11, 2020.
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Interview with Paul J. Young, PhD, author of When Should Clinicians Act on Non–Statistically Significant Results From Clinical Trials?
Don Berwick, MD, MPP, of the Institute for Healthcare Improvement, discusses choices societies and the medical profession can make to improve health care and reduce inequities as we move out of the acute phase of the coronavirus pandemic.
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Anne Schuchat, MD, Principal Deputy Director of the Centers for Disease Control and Prevention (CDC), discusses evolution of CDC guidance and latest developments in the COVID-19 pandemic. Recorded Friday May 1, 2020.
The US spends more on health care as a proportion of its GDP than any other nation. Will the COVID-19 pandemic reduce or accelerate that spending? Sherry Glied, PhD, Dean and Professor of Public Service at New York University, explains. Recorded Monday, April 27, 2020.
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The Potential Effects of Coronavirus on National Health Expenditures
Interview with Michael Silverstein, MD, MPH, USPSTF member and coauthor of Primary Care Interventions for Prevention and Cessation of Tobacco Use in Children and Adolescents: US Preventive Services Task Force Recommendation Statement
Marc Lipsitch, DPhil, an infectious diseases epidemiologist developing biological and modeling approaches to pathogen transmission and outbreaks, discusses evolution of the COVID-19 pandemic in summer and fall 2020. Originally recorded April 22, 2020.
Interview with Aaron S. Kesselheim, MD, JD, MPH, author of Increasing Access to FDA Inspection Reports on Irregularities and Misconduct in Clinical Trials
Rochelle Walensky, MD, MPH, of Harvard University discusses public health strategies and policies for lifting shelter-in-place and quarantine and for returning the US to a new post-first-wave normal. Recorded Monday April 20, 2020.
Interview with Madison Kilbride, PhD, author of The Need to Improve the Clinical Utility of Direct-to-Consumer Genetic Tests: Either Too Narrow or Too Broad
JAMA Health Forum editors John Ayanian, MD, MPP, and Melinda Buntin, PhD, discuss changes in US health care and health policy driven by the coronavirus pandemic. Recorded April 16, 2020.
Interview with Jeffrey A. Linder, MD, author of Delayed Antibiotic Prescriptions in Ambulatory Care: Reconsidering a Problematic Practice
New York City coronavirus update from Mitchell Katz, MD, President and CEO of NYC Health + Hospitals, the largest municipal public health system in the United States. Recorded April 13, 2020.
US states are taking the lead in managing the COVID-19 pandemic. What can state governors expect from the federal government and from the US Department of Health and Human Services? Governor Mike Leavitt from Leavitt Partners joins JAMA Editor Howard Bauchner, MD, in this live Q&A. Recorded April 8, 2020.
NIAID Director and Presidential Coronavirus Task Force Advisor Anthony Fauci, MD, discusses recent developments in the global COVID-19 pandemic with JAMA Editor Howard Bauchner, MD. Recorded April 8, 2020.
Questions about testing, chloroquine toxicity, duration of immunity and reinfection, and what to expect next are gripping the US as the novel coronavirus spreads. JAMA Associate Editor Preeti Malani, MD, professor of medicine and Chief Health Officer at the University of Michigan, discusses recent developments in a live conversation with JAMA Editor in Chief Howard Bauchner. Recorded on April 6, 2020.
Interview with Chien-Wen W Tseng, MD, MPH, USPSTF member and coauthor of Screening for Bacterial Vaginosis in Pregnant Persons to Prevent Preterm Delivery: US Preventive Services Task Force Recommendation Statement
Infectious epidemics have always driven change and triggered discrimination in human societies. Frank Snowden, DPhil, Professor Emeritus of History and History of Medicine at Yale University and author of Epidemics and Society: From the Black Death to the Present (Yale University Press, 2019), puts the COVID-19 pandemic in historical context.
Interview with Sandro Galea, MD, author of The Role of Physicians in Addressing Social Determinants of Health
Noninvasive ventilation (NIV), working with dying patients’ families, use of experimental therapies, and more. JAMA Associate Editor Derek Angus, MD, MPH, Distinguished Professor and Chair of Critical Care Medicine at the University of Pittsburgh, provides a COVID-19 ICU management update.
Watch the recording of this livestream
How does the current pandemic compare to historical infectious outbreaks and what can we expect in summer and fall of 2020? Nicholas Christakis, MD, PhD, MPH, director of the Human Nature Lab, Co-director of the Institute of Network Science, and Sterling Professor of Social and Natural Science at Yale University, discusses the epidemiology of COVID-19.
Hospitals need ways to make rational, fair decisions about who gets ICU beds and ventilators if COVID-19 patients overwhelm capacity. Douglas B. White, MD, MAS, Director of the Program on Ethics and Decision Making in Critical Illness at the University of Pittsburgh, discusses a framework for those decisions and a guideline he helped develop for allocation of scarce resources in public health emergencies.
As COVID-19 spreads globally, populations who survive their illness will become immune. Mayo Vaccine Research Group Director Gregory Poland, MD, discusses antibody responses, duration of immunity, vaccine safety, and the prospects for using convalescent serum to passively immunize people unexposed to SARS-CoV-2.
The ARDS in COVID-19 patients appears more responsive to PEEP and prone ventilation, but seems to require prolonged ventilation and may be associated with myocardial injury. Michelle N. Gong, MD, MS, Chief of Critical Care Medicine at Montefiore Medical Center in the Bronx, discusses her department's experience managing critically ill coronavirus patients, procuring diagnostic tests and personal protective equipment (PPE) for her staff, and more.
The strategy for managing the COVID-19 pandemic has shifted from containment to mitigation. What does that mean for US hospitals and health systems? Kaiser Permanente Executive Vice President Stephen M. Parodi, MD, discusses telemedicine, protecting health care workers, equipment allocation planning, and more.
Diagnostic testing, NSAIDs, ACE Inhibitors, antivirals, and more. Anthony Fauci, MD from NIAID discusses latest developments in the spread and clinical management of COVID-19 and the SARS-CoV-2 virus with JAMA Editor Howard Bauchner, MD.
JAMA Coronavirus Resource Center
Coronavirus testing will help countries manage coronavirus disease 2019 (COVID-19) but will raise questions about how to counsel patients about their test results. The CDC's Deputy Director for Infectious Diseases Jay C. Butler, MD, talks with JAMA Editor Howard Bauchner about what to advise healthy patients with positive PCR results, sick patients with negative test results, exposed health care workers, and more.
Physicians in Lombardy, Italy, have been overwhelmed by COVID-19 patients requiring critical care. Based on an existing ECMO center network they developed an ICU network to rapidly identify, triage, and manage patients infected with SARS-2-CoV. Maurizio Cecconi, MD, of Humanitas University in Milan discusses the region’s approach to the surge, including clinical and supply management, health care worker training and protection, and ventilation strategies, with JAMA Editor Howard Bauchner.
Read the article:
Critical Care Utilization for the COVID-19 Outbreak in Lombardy, Italy: Early Experience and Forecast During an Emergency Response
Interview with Victor M. Montori, MD, MSC, author of When Guidelines Recommend Shared Decision-making
Coronavirus testing, mortality, vaccine development, containment vs mitigation, and more. JAMA Editor Howard Bauchner, MD, interviews US NIAID Director Anthony Fauci, MD, about the latest developments in SARS-CoV-2 science and global spread of infection.
JAMA Coronavirus Resource Page
Interview with Michael J. Barry, MD, Task Force member and coauthor of Screening for Hepatitis C Virus Infection in Adolescents and Adults: US Preventive Services Task Force Recommendation Statement
Interview with Jonathan A. Patz, MD, MPH, author of A Low-Carbon Future Could Improve Global Health and Achieve Economic Benefits
Interview with Ezekiel J. Emanuel, M.D., Ph.D., author of The Inevitable Reimagining of Medical Education
Interview with Chyke A Doubeni, MD, MPH, author of Screening for Cognitive Impairment in Older Adults: US Preventive Services Task Force Recommendation Statement
Interview with David Naylor, MD DPhil, author of The Evolution of Schools of Thought in Medicine: Healthy Tensions
JAMA Author Interviews is taking on a new look! Be sure to subscribe to Conversations with Dr Bauchner, a podcast that features the same insightful interviews with leading researchers and thinkers in health care. Covering a broad range of practice-changing research and important innovations, Conversations with Dr Bauchner is a convenient way to stay current with the most pressing issues facing medicine and healthcare. Listen and subscribe at jamanetworkaudio.com.
By mid-February 2020 there were 60,000 confirmed cases of COVID-19, the vast majority diagnosed in Hubei Province (including Wuhan city) in mainland China. China CDC Chief Epidemiologist Zunyou Wu, MD, PhD discusses the latest COVID-19 developments in the country with JAMA Editor in Chief Howard Bauchner, MD.
In February 2020 the nature of the 2019-nCoV outbreak is still slowly coming into focus but it appears to be acting more like bad pandemic influenza (efficient spread, overall lower mortality) than like SARS (less efficient spread, overall higher mortality). Anthony Fauci, MD, of the US National Institute of Allergy and Infectious Diseases (NIAID) discusses the latest developments with JAMA Editor in Chief Howard Bauchner.
Coronavirus Resource Center
Interview with Jenny A. Doust, BMBS, author of Potential Consequences of Changing Disease Classifications
Interview with Jack Resneck, MD, author of Refocusing Medication Prior Authorization on Its Intended Purpose
Interview with Anthony S. Fauci, MD, author of Coronavirus Infections—More Than Just the Common Cold
Interview with I Glenn. Cohen, JD, author of Ethical and Legal Aspects of Ambient Intelligence in Hospitals
Interview with Maya M. Hammoud, MD, MBA, author of Improving the Residency Application and Selection Process: An Optional Early Result Acceptance Program
Interview with Donna Michelle Zulman, MD, and Abraham Verghese, MD, authors of Practices to Foster Physician Presence and Connection With Patients in the Clinical Encounter
Interview with Claire J. Creutzfeldt, MD, author of Treatment Decisions for a Future Self: Ethical Obligations to Guide Truly Informed Choices
Interview with Julia A. Segre, Ph.D., author of Manipulating the Human Microbiome to Manage Disease
Interview with Mercedes R. Carnethon, PhD, author of Disparities Research, Disparities Researchers, and Health Equity
Interview with Anthony S. Fauci, MD, author of Comorbidities in Persons With HIV: The Lingering Challenge
Interview with Michael J. Barry, MD, USPSTF member and coauthor of Screening for Abdominal Aortic Aneurysm: US Preventive Services Task Force Recommendation Statement
Interview with Mark D. Huffman, MD, MPH, author of Implementation Strategies for Cardiovascular Polypills
Interview with Amol S. Navathe, MD, PhD, author of Addressing Bias in Artificial Intelligence in Health Care
Interview with Stephen Baldassarri, author of Vaping—Seeking Clarity in a Time of Uncertainty
Interview with Pascale Carayon, PhD, author of Improving the System to Support Clinician Well-being and Provide Better Patient Care
Interview with John P. A. Ioannidis, MD, DSc, author of Neglecting Major Health Problems and Broadcasting Minor, Uncertain Issues in Lifestyle Science
Interview with Deborah Dowell, M.D., M.P.H., author of Patient-Centered Reduction or Discontinuation of Long-term Opioid Analgesics: The HHS Guide for Clinicians
Interview with William H. Shrank, MD, MSHS, author of Waste in the US Health Care System: Estimated Costs and Potential for Savings
Interview with S Claiborne Johnston, MD, PhD, author of The Risk and Cost of Limited Clinician and Patient Accountability in Health Care
Interview with Melissa A. Simon, MD, MPH, Task Force member and coauthor of Screening for Asymptomatic Bacteriuria in Adults: US Preventive Services Task Force Recommendation Statement
Interview with Francisco G. Cigarroa, MD, author of The Advancing American Kidney Health Executive Order: An Opportunity to Enhance Organ Donation
Interview with Frank B. Hu, MD, PhD, author of Can Plant-Based Meat Alternatives Be Part of a Healthy and Sustainable Diet?
Interview with Benjamin Daniel Sommers, MD, PhD, author of Medicaid Expansion and Health: Assessing the Evidence After Five Years
Interview with Anna D. Sinaiko, Ph. D., author of What Is the Value of Market-Wide Health Care Price Transparency?
Interview with Michael J. Barry, MD, USPSTF member and coauthor of Medication Use to Reduce Risk of Breast Cancer: US Preventive Services Task Force Recommendation Statement
Interview with Yngvild Olsen, M.D., M.P.H., author of Lessons Learned From the Opioid Epidemic
Interview with Karina W. Davidson, PhD, MASc, author of Screening for Social Determinants of Health: The Known and Unknown
Interview with Carol M Mangione, MD MSPH, USPSTF member and coauthor of Risk Assessment, Genetic Counseling, and Genetic Testing for BRCA-Related Cancer: US Preventive Services Task Force Recommendation Statement
Audio at 5:55 was changed to reflect a revised risk increase statement.
Interview with Joanna Paladino, MD, author of Communication Strategies for Sharing Prognostic Information With Patients: Beyond Survival Statistics
Interview with Daniel Brodie, MD, author of Extracorporeal Life Support for Adults With Respiratory Failure and Related Indications: A Review
Interview with Gary H. Gibbons, M.D., author of Accelerating the Science of SCD Therapies—Is a Cure Possible?
Interview with Alexandra K. Glazier, JD, MPH, author of Success of Opt-In Organ Donation Policy in the United States
Interview with Chyke A Doubeni, MD, MPH, USPSTF member and coauthor of Screening for Pancreatic Cancer: US Preventive Services Task Force Reaffirmation Recommendation Statement
Interview with Michael Nurok, MBChB, PhD, author of Relative Value Units and the Measurement of Physician Performance
Interview with Robert M. Wachter, MD, author of Reimagining Specialty Consultation in the Digital Age: The Potential Role of Targeted Automatic Electronic Consultations
Interview with Jennifer L. Swails, MD, author of The Conundrum of the United States Medical Licensing Examination Score Reporting Structure
Interview with Melissa A Simon, MD MPH, USPSTF member and coauthor of Screening for Hepatitis B Virus Infection in Pregnant Women: US Preventive Services Task Force Reaffirmation Recommendation Statement
Interview with Randall S. Stafford, MD, PhD, MHS, author of A Practical Approach to Low-Dose Aspirin for Primary Prevention
Interview with S. Claiborne Johnston, MD, PhD, author of Academic Medical Centers: Too Large for Their Own Health?
Interview with John W Epling, MD, MSEd, Task Force member and co-author of Preexposure Prophylaxis for the Prevention of HIV Infection: US Preventive Services Task Force Recommendation Statement
Interview with Paul A. Volberding, MD, and Hyman Scott, MD MPH, authors of HIV Screening and Preexposure Prophylaxis Guidelines: Following the Evidence
Interview with Marissa A. Hendrickson, MD, author of The Review of Systems, the Electronic Health Record, and Billing
Interview with Anthony S. Fauci, MD, author of Durable Control of HIV Infection in the Absence of Antiretroviral Therapy: Opportunities and Obstacles
Interview with Alan Leshner, PhD, author of Medication-Based Treatment to Address Opioid Use Disorder
Interview with Andrew A. Nierenberg, MD, author of Evolving Issues in the Treatment of Depression
Interview with Robert M. Wachter, MD, author of Restricting the Number of Open Patient Records in the Electronic Health Record: Is the Record Half Open or Half Closed?
Interview with David M. Cutler, PhD, author of Life and Death in Norway and the United States
Interview with Nancy L. Keating, MD, MPH, author of New Federal Requirements to Inform Patients About Breast Density: Will They Help Patients?
Interview with Benjamin Tolchin, MD, MS, author of Treatment of Patients With Psychogenic Nonepileptic Attacks
Interview with Robert M. Califf, MD, author of Lowering Cost and Increasing Access to Drugs Without Jeopardizing Innovation
Interview with Michael Silverstein, MD, MPH, USPSTF member and coauthor of Screening for Elevated Blood Lead Levels in Children and Pregnant Women: US Preventive Services Task Force Recommendation Statement
Interview with John A. Baron, M.D., author of Vitamin D as Cancer Therapy?: Insights From 2 New Trials
Interview with Kevin A. Schulman, MD, author of The Implications of “Medicare for All” for US Hospitals
Interview with David A. Asch, MD, MBA, author of The Uncertain Effect of Financial Incentives to Improve Health Behaviors
Interview with Neil Skolnik, M.D., author of Reexamining Recommendations for Treatment of Hypercholesterolemia in Older Adults
Interview with Ezekiel J. Emanuel, M.D., Ph.D., author of Next Phase in Effective Cost Control in Health Care
Interview with Elizabeth O'Connor, PHD, author of Interventions to Prevent Perinatal Depression: Evidence Report and Systematic Review for the US Preventive Services Task Force
Interview with Sonoo Thadaney-Israni, MBA, and Abraham Verghese, MD, MACP, authors of Humanizing Artificial Intelligence
Interview with Alex R Kemper, MD, MPH, MS, Task Force member and co-author of Interventions to Prevent Child Maltreatment: US Preventive Services Task Force Recommendation Statement
Interview with Susan J. Curry, PhD, author of Screening and Behavioral Counseling Interventions to Reduce Unhealthy Alcohol Use in Adolescents and Adults: US Preventive Services Task Force Recommendation Statement
Interview with John W Epling, MD, MSEd, Task Force member and co-author of Screening for Intimate Partner Violence, Elder Abuse, and Abuse of Vulnerable Adults: US Preventive Services Task Force Final Recommendation Statement
Interview with Chyke A Doubeni, M.D., F.R.C.S., M.P.H., Task Force member and co-author of Behavioral Weight Loss Interventions to Prevent Obesity-Related Morbidity and Mortality in Adults: US Preventive Services Task Force Recommendation Statement
Interview with Carol M Mangione, MD MSPH, Task Force member and co-author of Screening for Cervical Cancer: US Preventive Services Task Force Recommendation Statement
Interview with Seth Landefeld, MD, member of the US Preventative Services Task Force, on Screening for Atrial Fibrillation With Electrocardiography: US Preventive Services Task Force Recommendation Statement
Interview with Michael J. Barry, MD, Task Force member and co-author of Screening for Peripheral Artery Disease and Cardiovascular Disease Risk Assessment With the Ankle-Brachial Index: US Preventive Services Task Force Recommendation Statement
Interview with Chien-Wen Tseng, MD, MPH, Task Force member and co-author of Screening for Osteoporosis to Prevent Fractures: US Preventive Services Task Force Recommendation Statement
Interview with Seth Landefeld, MD, Task Force member and co-author of Screening for Cardiovascular Disease Risk With Electrocardiography: US Preventive Services Task Force Recommendation Statement
Interview with Alex H Krist, MD, MPH, Task Force member and co-author of Screening for Prostate Cancer: US Preventive Services Task Force Recommendation Statement
Interview with Alex H Krist, MD, MPH, Task Force member and co-author of Vitamin D, Calcium, or Combined Supplementation for the Primary Prevention of Fractures in Community-Dwelling Adults: US Preventive Services Task Force Recommendation Statement, and Interventions to Prevent Falls in Community-Dwelling Older Adults: US Preventive Services Task Force Recommendation Statement
Interview with Christopher JL. Murray, MD, DPhil, author of The State of US Health, 1990-2016: Burden of Diseases, Injuries, and Risk Factors Among US States
Interview with John W Epling, MD, MSEd, Task Force member and co-author of Behavioral Counseling to Prevent Skin Cancer: US Preventive Services Task Force Recommendation Statement
Interview with Dr. Ashish Jha, MD, MPH, about his study using Organization for Economic Cooperation and Development (OECD) data to compare health care infrastructure, outcomes, and prices in the US and other high-income countries to identify the sources of spending that make US health care so expensive.
Interview with Michael J. Barry, MD, Task Force member and co-author of Screening for Ovarian Cancer: US Preventive Services Task Force Recommendation Statement
Interview with Alex R Kemper, MD, MPH, MS, Task Force member and co-author of Screening for Adolescent Idiopathic Scoliosis: US Preventive Services Task Force Recommendation Statement
Interview with Maureen Phipps, MD, Task Force member and co-author of Hormone Therapy for the Primary Prevention of Chronic Conditions in Postmenopausal Women: US Preventive Services Task Force Recommendation Statement
Interview with Jeffrey Alan. Golden, MD, author of Deep Learning Algorithms for Detection of Lymph Node Metastases From Breast Cancer: Helping Artificial Intelligence Be Seen
Interview with JoAnn E. Manson, MD, DrPH, author of Menopausal Hormone Therapy and Long-Term All-Cause and Cause-Specific Mortality: The Women’s Health Initiative Randomized Trials
Interview with Alex R Kemper, MD, MPH, MS, Task Force member and co-author of Vision Screening in Children Aged 6 Months to 5 Years: US Preventive Services Task Force Recommendation Statement
Interview with Stuart M. Butler, PhD, MA, BSc, author of State Flexibility for Medicaid: How Much?
Interview with Ann C. McKee, M.D., author of Clinicopathological Evaluation of Chronic Traumatic Encephalopathy in Players of American Football
Interview with Susan J. Curry, PhD, author of Behavioral Counseling to Promote a Healthful Diet and Physical Activity for Cardiovascular Disease Prevention in Adults Without Cardiovascular Risk Factors: US Preventive Services Task Force Recommendation Statement
Interview with David C. Grossman, MD, MPH, author of Screening for Obesity in Children and Adolescents: US Preventive Services Task Force Recommendation Statement
Interview with Timothy E. McAlindon, MD,MPH, author of Effect of Intra-articular Triamcinolone vs Saline on Knee Cartilage Volume and Pain in Patients With Knee Osteoarthritis: A Randomized Clinical Trial
Whole-genome sequencing is now easily done for very little cost. It is not known how to interpret the results of this testing. Healthy individuals should not have this performed. If someone has a reason to suspect a particular disease with a known genetic association, then whole-genome or targeted sequencing is reasonable to pursue.
Interview with Charles Landefeld, MD, author of Screening for Thyroid Cancer: US Preventive Services Task Force Recommendation Statement
Interview with Maureen G. Phipps, MD, MPH, Task Force member and co-author of Screening for Preeclampsia: US Preventive Services Task Force Recommendation Statement
Interview with Gail Hayward, MA (Oxon) D.Phil MRCP MRCGP, author of Effect of Oral Dexamethasone Without Immediate Antibiotics vs Placebo on Acute Sore Throat in Adults: A Randomized Clinical Trial
This podcast discusses the latest research into the workings of the lung microbiome and how it will affect future diagnosis and treatment of respiratory diseases. Related article: The Lung Microbiome: Key to Respiratory Ills?
This Medical News podcast features an interview with Barry Marshall, MD, who codiscovered the stomach bug H pylori in 1982.
Interview with Alex H Krist, MD, MPH, Task Force member and co-author of Screening for Celiac Disease: US Preventive Services Task Force Recommendation Statement
Interview with Freddie C. Hamdy, MD, FRCSEd(Urol), and Jenny L Donovan, PhD, FMedSci, authors of Patient-Reported Outcomes Following Treatment for Localized Prostate Cancer: Helping Decision Making for Patients and Their Physicians
Recent guidelines for how to best manage septic shock have changed. Gone are recommendations for central venous oxygen saturation monitoring and goal-directed therapy. In is the concept that septic shock be treated as an emergency with rapid administration of antibiotics and large amounts of fluids. Our discussants Derek C. Angus, MD, MPH, and Michael D. Howell, MD, MPH, discuss why these recommendations have changed. This is the second podcast in the Surviving Sepsis guideline series. The first podcast reviewed what recommendations are in the guideline itself.
Article discussed in this episode: Management of Sepsis and Septic Shock
Speakers: JAMA Associate Editor Derek C. Angus, MD, MPH, University of Pittsburgh, and Michael D. Howell, MD, MPH, University of Chicago.
Interview with Maureen G. Phipps, MD, MPH, Task Force member and co-author of Screening for Gynecologic Conditions With Pelvic Examination: US Preventive Services Task Force Recommendation Statement
In 2017 the Society for Critical Care Medicine updated its guidelines for sepsis management. These new guidelines differ significantly from ones in the past in that they no longer recommend protocolized resuscitation and emphasize early and aggressive fluid resuscitation when patients present with septic shock. This is the first podcast in the Surviving Sepsis guideline series. The next episode discusses why the new sepsis guideline changed.
Article discussed in this episode: Management of Sepsis and Septic Shock
Speakers:
Laura Evans, MD, MSc, of Bellevue Hospital and NYU Medical Center
Andrew Rhodes, MBBS, MD, of St George’s University Hospitals NHS Trust and co-chair of the Surviving Sepsis guideline panel
Mitchell M. Levy, MD, of the Alpert Medical School of Brown University and Rhode Island Hospital
Can testosterone gel improve memory, correct anemia, increase bone density or prevent the growth of coronary artery plaque in older men with low testosterone levels? Four new studies in JAMA and JAMA Internal Medicine found improvement in some of these measures.
Articles discussed in this episode:
• Testosterone Treatment and Coronary Artery Plaque Volume in Older Men With Low Testosterone
• Testosterone Treatment and Cognitive Function in Older Men With Low Testosterone and Age-Associated Memory Impairment
• Effect of Testosterone Treatment on Volumetric Bone Density and Strength in Older Men With Low Testosterone: A Controlled Clinical Trial
• Association of Testosterone Levels With Anemia in Older Men: A Controlled Clinical Trial
Rudolph Tanzi, PhD, of Harvard University, and Berislav Zlokovic, MD, PhD, of the University of Southern California, discuss what the future holds for Alzheimer Disease research and treatment.
Interview with Julie Rani Nangia, BA, MD, author of Effect of a Scalp Cooling Device on Alopecia in Women Undergoing Chemotherapy for Breast Cancer: The SCALP Randomized Clinical Trial, and Hope S. Rugo, MD, author of Association Between Use of a Scalp Cooling Device and Alopecia After Chemotherapy for Breast Cancer
Workplace violence–related injuries occur disproportionately in health care settings. In this podcast, we discuss how individual clinicians should manage violent patients who might attack them. Article discussed in this episode: Ensuring Staff Safety When Treating Potentially Violent Patients
Interview with Alex H. Krist, MD, MPH, Task Force member and co-author of Screening for Obstructive Sleep Apnea in Adults: US Preventive Services Task Force Recommendation Statement
Interview with Alex R. Kemper, MD, MPH, MS, Task Force member and co-author of Folic Acid Supplementation for the Prevention of Neural Tube Defects: US Preventive Services Task Force Recommendation Statement
Between 8% and 10% of the population will have a seizure at one point in life. It's important to distinguish seizures from other entities that can look like them and, once a diagnosis of a seizure is established, know how to treat them. In this JAMA Clinical Review podcast, we discuss seizures and epilepsy with Jay Gavvala, MD, author of New-Onset Seizure in Adults and Adolescents: A Review.
Article discussed in this episode:
New-Onset Seizure in Adults and Adolescents: A Review
Violence against health care workers is increasing. With fewer mental health services available, health care workers have disproportionate exposure to potentially dangerous patients. This article reviews the experience of one nurse who was severely injured by a patient and the lessons learned by the hospital where the incident occurred regarding minimizing the risk of staff injury when providing care for potentially violent patients. We interview Robert P. Roca, MD, MPH, MBA; Antonio DePaolo, PhD; Ernestine Cosby, RN; and Bolarin Kehinde, RN, to shed light on this serious issue.
Article discussed in this episode: Ensuring Staff Safety When Treating Potentially Violent Patients
Interview with Ann E. Kurth, PhD, RN, MSN, MPH, author of Serologic Screening for Genital Herpes Infection: US Preventive Services Task Force Recommendation Statement
Interview with Roger L. Zemek, MD, author of Association Between Early Participation in Physical Activity Following Acute Concussion and Persistent Postconcussive Symptoms in Children and Adolescents
Interview with Christopher JL. Murray, MD, DPhil, author of US County-Level Trends in Mortality Rates for Major Causes of Death, 1980-2014
Approximately one-third of all medical school graduates report having been abused as students. Medical student and resident abuse has long been considered unacceptable behavior but still persists in the teaching environment. In this podcast we discuss how students and residents might respond to these events. We interview Geoffrey Young, MD, from the Association of American Medical Colleges and Thomas J. Nasca, MD, from the Accreditation Council for Graduate Medical Education, who discuss how they expect medical schools to respond to abusive behaviors and what resources are available to students and residents who have been abused to report those experiences without fearing retribution.
Article discussed in this episode:
Medical Student Mistreatment
Interview with Douglas K. Owens, MD, MS, USPSTF Task Force member and coauthor of Statin Use for the Primary Prevention of Cardiovascular Disease in Adults: US Preventive Services Task Force Recommendation Statement
Medicare recently developed a star rating system to help consumers determine the quality of care delivered at various hospitals. This rating system was considered controversial by many. In this podcast we discuss the rating system with one of its critics, Karl Y. Bilimoria, MD, MS, and with Kate Goodrich, MD, the Director of the Center for Clinical Standards and Quality at Medicare.
Article discussed in this episode:
The New CMS Hospital Quality Star Ratings: The Stars Are Not Aligned
This Medical News podcast discusses the Human Genome Project-write with Harvard geneticist, George Church, PhD.
Interview with Ann E. Kurth, PhD, RN, MSN, MPH, Task Force member and co-author of Primary Care Interventions to Support Breastfeeding: US Preventive Services Task Force Recommendation Statement
In this episode of JAMA Professionalism: Best Practice, Edward H. Livingston, MD looks at the case of a physician requesting prescription medication from a colleague to examine professional boundaries between physicians and options for managing those boundaries. Shiphra Ginsburg, MD and Wendy Levinson, MD, authors of the related article, join Dr Livingston to discuss the best options for handling this challenging situation. Arthur S. Hengerer, MD, chair of the Federation of State Medical Boards discusses the legal and licensure ramifications of physicians prescribing for other clinicians and Kate E. Engelhardt, MD, and D. Brock Hewitt, MD, MPH, practicing physicians, relate their experience with other clinicians asking them to prescribe medications.
This Medical News podcast features a Q&A with CDC Director Tom Frieden, MD, commemorating the agency’s historic 70th anniversary. The interview was recorded on August 8th, 2016.
Interview with Pieter A. Cohen, MD, author of The Supplement Paradox: Negligible Benefits, Robust Consumption
Nearly all women experience some element of nausea and vomiting during their pregnancies. In this podcast we review the entire spectrum of disease all the way up to hyperemesis gravidarum and how to provide care for women experiencing these problems.
Article discussed in this episode:
Treatments for Hyperemesis Gravidarum and Nausea and Vomiting in Pregnancy
When managing septic shock, passive leg raising is the best test to determine if a patient is likely to respond to a fluid bolus, better than CVP lines or even bedside ultrasound. Dr Najib Ayas, Associate professor of Critical Care Medicine at the University of British Columbia, discusses shock management from the context of his Rational Clinical examination article in the September 27, 2016 issue of JAMA, entitled “Will This Hemodynamically Unstable Patient Respond to a Bolus of Intravenous Fluids?”
Interview with Jeffrey L Saver, M.D., author of Time to Treatment With Endovascular Thrombectomy and Outcomes From Ischemic Stroke: A Meta-analysis
What to do when the wrong procedure is performed? In this first installment of JAMA Performance Improvement: Do No Harm we explore the options for dealing with this very difficult problem with Tami Minnier, RN, MSN, Paul Phrampus, MD, Linda Waddell, RN, MSN, and David Baker, MD, MPH, FACP. Air traffic audio courtesy of LiveATC.net, used with permission.
Interview with John M. Jakicic, PhD, author of Effect of Wearable Technology Combined With a Lifestyle Intervention on Long-term Weight Loss: The IDEA Randomized Clinical Trial
Interview with Vivian S. Lee, MD, PhD, MBA;, author of Implementation of a Value-Driven Outcomes Program to Identify High Variability in Clinical Costs and Outcomes: Association With Reduced Cost and Improved Quality, and Michael E. Porter, PhD, author of From Volume to Value in Health Care: The Work Begins
Patrick Soon-Shiong, MD, physician-scientist and entrepreneur, talks about the National MoonShot Initiative, his MoonShot 2020 Program, as well as promising approaches in cancer immunotherapy. This podcast was originally recorded on June 3, 2016
Interview with Francisco A.R. García, MD, MPH, author of Screening for Latent Tuberculosis Infection in Adults: US Preventive Services Task Force Recommendation Statement
Interview with Joel G. Ray, MD, MSc, FRCPC, author of Association Between MRI Exposure During Pregnancy and Fetal and Childhood Outcomes
Drug prices continue to rise in the US. Many solutions have been proposed but few have been implemented. Drs. Janet Woodcock from the FDA and Aaron Kesselheim, author of The High Cost of Prescription Drugs in the United States from the Harvard Medical School discuss the role of brand name drugs and generics and how they influence the cost of pharmaceuticals.
Also see The Cost of US Pharmaceutical Price Reductions: A Financial Simulation Model of R&D Decisions by Thomas A. Abbott and John A. Vernon.
Introducing a new series of JAMA articles on professionalism, discussed from the perspective of how clinicians should address challenging clinical situations and adverse events in their medical practice. In the first episode of the accompanying podcast, JAMA Professionalism: Best Practice, we interview Wendy Levinson, MD, and Jensen Yeung, MD, authors of Disclosure of Medical Error, which appeared in the August 16, 2016 issue of JAMA, as well as Thomas H. Gallagher, MD.
Interview with Dhruv S. Kazi, MD, MSc, MS, author of Cost-effectiveness of PCSK9 Inhibitor Therapy in Patients With Heterozygous Familial Hypercholesterolemia or Atherosclerotic Cardiovascular Disease
Edward H. Livingston, MD, discusses the British Columbia Ministry of Health’s 2015 guidelines on clinical management of opioid use disorder in adults with Keith Ahamad, MD, Evan Wood, MD, PhD, ABIM, FRCPC, Tony L. Yaksh, PhD, and Humayun J. Chaudhry, DO, MS, MACP, FACOI.
Articles and resources discussed in this episode:
- Opioid Use and Addiction Microsite,
- Clinical Management of Opioid Use Disorder (JAMA Clinical Guidelines Synopsis),
- The Vancouver Opioid Use Disorder Guideline,
- Model Policy on DATA 2000 And Treatment of Opioid Addiction in the Medical Office
Interview with David Grossman, MD, author of Screening for Lipid Disorders in Children and Adolescents: US Preventive Services Task Force Recommendation Statement
Interview with Axel Linke, MD, author of Effect of a Cerebral Protection Device on Brain Lesions Following Transcatheter Aortic Valve Implantation in Patients With Severe Aortic Stenosis: The CLEAN-TAVI Randomized Clinical Trial
Interview with Barbara E. Murray, MD, author of Infectious Disease Expert Sees Threat From Colistin-Resistant Superbug
Interview with Michael P. Pignone, MD, MPH, author of Screening for Skin Cancer: US Preventive Services Task Force Recommendation Statement
Richard N. Rosenthal, MD discusses a randomized clinical trial demonstrating the efficacy of an implantable buprenorphine-releasing device for treating opioid use disorder.
Interview with Dorry Segev, MD, PhD, author of HIV and Transplantation: New Reasons for HOPE
Lyme disease is very common in certain regions of the country and is caused by the spirochete Borrelia bergdorferi. Lyme disease is transmitted by tick bites and in this podcast we review the discovery of Lyme disease, its major clinical features, and how to diagnose and treat it, as told by Dr Alan Steere, Dr Lyndon Hu, and Dr Paul Auerwerter.
Related article: Review of Lyme Disease, Human Granulocytic Anaplasmosis, and Babesiosis
Interview with Ezekiel J. Emanuel, MD, PhD, author of Attitudes and Practices of Euthanasia and Physician-Assisted Suicide in the United States, Canada, and Europe
Persistent diarrhea is a poorly recognized syndrome in all populations that requires proper assessment and diagnosis to ensure that affected individuals receive the treatment needed to experience improvement of clinical symptoms. Listen to Drs Herbert DuPont and Annie Feagins discuss how to diagnose and treat diarrhea. Related article: Persistent Diarrhea
Interview with Jeff D. Williamson, MD, MHS, author of Intensive vs Standard Blood Pressure Control and Cardiovascular Disease Outcomes in Adults Aged ≥75 Years: A Randomized Clinical Trial
Howard Bauchner, MD, Editor in Chief of JAMA, interviews Simon Chapman, MD, author of Association Between Gun Law Reforms and Intentional Firearm Deaths in Australia, 1979-2013
Interview with Douglas K. Owens, MD, MS, author of Screening for Colorectal Cancer: US Preventive Services Task Force Recommendation Statement
Dr Allen Steere discovered Lyme disease and discusses what he saw and did when confronted early in his career with a previously undescribed disease. Late stage disease, a form not commonly seen today, is discussed in detail since that is how the disease presented before its cause was determined.
Related article:
Review of Lyme Disease, Human Granulocytic Anaplasmosis, and Babesiosis
Interview with Ann E. Kurth, PhD, RN, MSN, MPH, author of Screening for Syphilis Infection in Nonpregnant Adults and Adolescents: US Preventive Services Task Force Recommendation Statement
Interview with Cynthia L. Ogden, PhD, author of Trends in Obesity Among Adults in the United States, 2005 to 2014
Interview with Gillian L. Booth, MD, author of Association of Neighborhood Walkability With Change in Overweight, Obesity, and Diabetes
Drs Stuart Spechler and Peter Kahrilis discuss GERD and esophagitis--how they occur and how they are treated. Dr Spechler also discusses a new hypothesis regarding how reflux esophagitis is caused that differs from the traditional teaching that acid and pepsin reflux into the esophagus and burn the mucosa layers.
Related articles:
Association of Acute Gastroesophageal Reflux Disease With Esophageal Histologic Changes
Turning the Pathogenesis of Acute Peptic Esophagitis Inside Out
Interview with Douglas B. White, MD, MAS, author of Prevalence of and Factors Related to Discordance About Prognosis Between Physicians and Surrogate Decision Makers of Critically Ill Patients
Attention-Deficit/Hyperactivity Disorder, or ADHD is a very common problem affecting about 10% of all adolescents. Children with ADHD have short attention spans, are hyperactive, talk a great deal, can be disruptive in the classroom etc.-features that are common in many adolescents. However, to have true ADHD, children must be significantly impaired by these problems. An array of medical and behavioral treatments can successfully help manage ADHD. These are reviewed in a series of articles appearing in the May 10, 2016, issue of JAMA. In this podcast, we discuss ADHD with the authors of some of those papers, Eugenia Chan, MD, MPH from Harvard and Philip Shaw, MD, PhD from the National Human Genome Research Institute.
Articles discussed in this episode:
- Treatment of Attention-Deficit/Hyperactivity Disorder in Adolescents: A Systematic Review
- Quantifying the Benefits and Risks of Methylphenidate as Treatment for Childhood Attention-Deficit/Hyperactivity Disorder
- Methylphenidate for Attention-Deficit/Hyperactivity Disorder in Children and Adolescents
Interview with Pascal Hammel, MD, author of Effect of Chemoradiotherapy vs Chemotherapy on Survival in Patients With Locally Advanced Pancreatic Cancer Controlled After 4 Months of Gemcitabine With or Without Erlotinib: The LAP07 Randomized Clinical Trial
Christine Curry, MD, PhD, assistant professor of obstetrics and gynecology at the University of Miami, discusses the challenges of keeping pregnant patients and her colleagues well-informed of the facts as Zika virus fears circulate.
Interview with Linden Hu, MD, author of Diagnosis, Treatment, and Prevention of Lyme Disease, Human Granulocytic Anaplasmosis, and Babesiosis: A Review
Interview with Céline Vetter, PhD, author of Association Between Rotating Night Shift Work and Risk of Coronary Heart Disease Among Women
Interview with Antoni Ribas, MD, PhD, author of Association of Pembrolizumab With Tumor Response and Survival Among Patients With Advanced Melanoma
Mononucleosis is a common disease of young adults manifested by lethargy, fever, pharyngitis, lymphadenopathy and splenomegaly. In this podcast, we review the clinical features of the disease and how good each of them is at establishing a diagnosis of mononucleosis. We also review how Epstein Barr virus was discovered as the cause of mononucleosis and talk to Mark H. Ebell, MD, MS, author of Does This Patient Have Infectious Mononucleosis? The Rational Clinical Examination Systematic Review.
Articles discussed in this episode:
- Does This Patient Have Infectious Mononucleosis? The Rational Clinical Examination Systematic Review (2016)
- Acute Lymphatic Leukemia and Infectious Mononucleosis (1931)
- Infectious Mononucleosis: Part I. Clinical Aspects (1935)
- Infectious Mononucleosis: Clinical Manifestations in Relation to EB Virus Antibodies (1968)
Interview with Kiros Berhane, PhD, author of Association of Changes in Air Quality With Bronchitic Symptoms in Children in California, 1993-2012
Interview with Raj Chetty, PhD, author of The Association Between Income and Life Expectancy in the United States, 2001-2014, and Angus Deaton, PhD, author of On Death and Money: History, Facts, and Explanations
Interview with William R. Phillips, MD, MPH, author of Screening for Chronic Obstructive Pulmonary Disease: US Preventive Services Task Force Recommendation Statement
Interview with Wendy C. King, PhD, author of Change in Pain and Physical Function Following Bariatric Surgery for Severe Obesity
Interview with Daniel C. Cherkin, PhD, author of Effect of Mindfulness-Based Stress Reduction vs Cognitive Behavioral Therapy or Usual Care on Back Pain and Functional Limitations in Adults With Chronic Low Back Pain: A Randomized Clinical Trial
An opioid abuse epidemic now plagues US healthcare. It was caused, in part, by overzealous advocacy for controlling chronic pain resulting in overuse of narcotics. There are now 2 million Americans addicted to opioids. The approach for treating chronic pain must change. In this podcast, we summarize recent CDC guidelines for the proper use of opioids for treating chronic pain.
Articles discussed in this episode:
- CDC Guideline for Prescribing Opioids for Chronic Pain— United States, 2016,
- The CDC Guideline on Opioid Prescribing: Rising to the Challenge (Yngvild Olsen, MD, MPH),
- The DSM-V definition for opioid use disorder and 11 point checklist
Interview with Saad B. Omer, MBBS, MPH, PhD, author of Association Between Vaccine Refusal and Vaccine-Preventable Diseases in the United States A Review of Measles and Pertussis
Polypharmacy is a rapidly worsening problem that hits elderly patients particularly hard. As patients grow older, they need more medications but at the same time become less capable of managing the complexity of drug treatments. In order to simplify treatment regimens for older patients, it is necessary to consider the evidence supporting treatment of various conditions and when the evidence is not particularly strong, reduce or eliminate medications accordingly. Diabetes management in the elderly is highlighted in this podcast with specific attention given to deintensifying diabetes treatment in the elderly.
Articles discussed in this episode:
- Polypharmacy in the Aging Patient: Glycemic Control in Older Adults With Type 2 Diabetes: A Review (Kasia J. Lipska, MD, MHS)
- Evaluation and Treatment of Older Patients With Hypercholesterolemia: A Clinical Review (Timo E. Strandberg, MD, PhD)
- Trends in Prescription Drug Use Among Adults in the United States From 1999-2012 (Elizabeth D. Kantor, PhD, MPH)
Interview with Lynn Babcock, MD, MS, author of Identifying Children and Adolescents at Risk for Persistent Postconcussion Symptoms
Interview with Michael P. Pignone, MD, MPH, author of Screening for Impaired Visual Acuity in Older Adults: US Preventive Services Task Force Recommendation Statement
Robert O. Bonow, MD, the editor-in-chief of JAMA Cardiology, the JAMA Network’s newest addition, discusses his editorial vision for the journal, as well as his insights on advances in the prevention and treatment of cardiovascular disease.
Interview with Clifford Deutschman, MD, MS, Mervyn Singer, MD and Derek Angus, MD, MPH, authors of The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)
Interview with John G. Laffey, MD, MA, author of Epidemiology, Patterns of Care, and Mortality for Patients With Acute Respiratory Distress Syndrome in Intensive Care Units in 50 Countries
Interview with David C. Grossman, MD, MPH, author of Screening for Autism Spectrum Disorder in Young Children: US Preventive Services Task Force Recommendation Statement
Community acquired pneumonia accounts for 600,000 hospital admissions a year. Many patients with this disease are quite ill and have a very high mortality. To save lives, the appropriate antibiotics should be given in a timely basis, but it is not clear what the best antibiotics are and how long they should be given. In this podcast we interview the author of a JAMA review on community acquired pneumonia, Dr Jonathan Lee, author of Antibiotic Therapy for Adults Hospitalized With Community-Acquired Pneumonia, who performed a systematic review of the literature to determine the best way to treat community acquired pneumonia.
The 2015-2020 US Dietary Guidelines for Americans were recently released. They are intended to provide guidance for health policy officials and clinicians regarding healthy diets and establishing goals for improving nutrition. These are important since bad eating habits are the underlying cause for a great deal of disease in the US and that these guidelines influence the operations of programs such as school lunch assistance, meals on wheels etc. Because these guidelines influence policy, they have been criticized by various investigators and special interest groups. Karen DeSalvo, MD, Acting Assistant Secretary for Health at HHS and author of Dietary Guidelines for Americans responds to some of these criticisms and explains how the guideline was created and what it is intended to do. Implementation of the guidelines dietary advice may be challenging and Deborah Clegg, RD, PhD, Professor of Internal Medicine at UCLA discusses how the various recommendations can be followed.
Interview with Martha Clare Morris, ScD, author of Association of Seafood Consumption, Brain Mercury Level, and APOE ε4 Status With Brain Neuropathology in Older Adults
Interview with Michael P. Pignone, MD, MPH, author of Screening for Depression in Adults: US Preventive Services Task Force Recommendation Statement
Peripheral neuropathy is a highly prevalent and morbid condition affecting 2% to 7% of the population. Patients frequently experience pain and are at risk of falls, ulcerations, and amputations. It is most commonly occurs in patients with diabetes. For most cases, the diagnosis and treatment of neuropathy can be made without complex testing or referral to specialists. Drs. Eva Feldman and Brian Callaghan from the University of Michigan Department of Neurology, authors of Distal Symmetric Polyneuropathy and Electrodiagnostic Tests in Polyneuropathy and Radiculopathy, explain how to manage neuropathy.
Interview with Justin E. Bekelman, MD, author of Comparison of Site of Death, Health Care Utilization, and Hospital Expenditures for Patients Dying With Cancer in 7 Developed Countries
Constipation is one of the most frequent problems clinicians are asked to deal with. Despite how common it is, constipation is frequently not treated adequately. In this podcast, Arnold Wald, MD, explains a stepwise approach to the management of constipation ranging from very simple measures to the most novel and complicated new medical therapies.
Interview with Gaëtan Deslée, MD, PhD, author of Lung Volume Reduction Coil Treatment vs Usual Care in Patients With Severe Emphysema: The REVOLENS Randomized Clinical Trial
Interview with Dalane W. Kitzman, MD, author of Effect of Caloric Restriction or Aerobic Exercise Training on Peak Oxygen Consumption and Quality of Life in Obese Older Patients With Heart Failure With Preserved Ejection Fraction: A Randomized Clinical Trial
Minor head trauma usually does not cause significant brain injury. To be safe, clinicians often obtain head CT scans to ensure no major injury is present. For minor head trauma (Glascow coma scale 13-15), the risk to benefit ratio for head CT is usually not in favor of getting CT scans. When the Canadian head CT rule or New Orleans Criteria are negative, there is a very small risk for missing a significant brain injury. Joshua Easter, MD from the Department of Emergency Medicine at the University of Virginia who authored a JAMA Rational Clinical Examination article on this topic is interviewed as is Frederick Rivara, from the Department of Pediatrics at the University of Washington who wrote an accompanying editorial. Michelle Mello, a Law Professor at Stanford, discusses the medical liability associated with not obtaining neuroimaging for minor head trauma.
Interview with Debbie A. Lawlor, PhD, author of Live-Birth Rate Associated With Repeat In Vitro Fertilization Treatment Cycles
Edward H. Livingston, MD discusses Graves disease with David Cooper, MD, author of Management of Graves Disease: A Review
Interview with John H. Sampson, MD, PhD, MHSc, MBA, author of Alternating Electric Fields for the Treatment of Glioblastoma
Interview with Roger Stupp, MD, author of Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial
Interview with Thomas L. Schwenk, MD, author of Resident Depression: The Tip of a Graduate Medical Education Iceberg
Interview with Ingrid M. Libman, MD, PhD, author of Effect of Metformin Added to Insulin on Glycemic Control Among Overweight/Obese Adolescents With Type 1 Diabetes
Interview with Alex B. Haynes, MD, MPH, author of Relationship Between Cesarean Delivery Rate and Maternal and Neonatal Mortality
Edward H. Livingston MD, explores the topic of prostate cancer screening in author interviews with:
- Dan Merenstein about losing a malpractice case despite following evidence-based medicine guidelines (PSA Screening — I Finally Won!).
- Otis Brawley about Prostate Cancer Incidence and PSA Testing Patterns in Relation to USPSTF Screening Recommendations.
- David F. Penson about The Pendulum of Prostate Cancer Screening.
- Victor M. Montori about The Connection Between Evidence-Based Medicine and Shared Decision Making.
Edward H. Livingston, MD, Deputy Editor of Clinical Reviews and Education discusses prostate cancer screening with Otis Brawley, MD, author of Prostate Cancer Incidence and PSA Testing Patterns in Relation to USPSTF Screening Recommendations and David F. Penson, MD, MPH, author of a related editorial entitled The Pendulum of Prostate Cancer Screening.
Edward H. Livingston, MD, Deputy Editor of Clinical Reviews and Education and Jon Tilburt, MD, from the Mayo Clinic explain prostate cancer screening. For more information, read the JAMA Patient Page on this topic.
Interview with Leonard B. Bacharier, MD, author of Early Administration of Azithromycin and Prevention of Severe Lower Respiratory Tract Illnesses in Preschool Children With a History of Such Illnesses: A Randomized Clinical Trial
Interview with Lee M. Jampol, MD, author of Panretinal Photocoagulation vs Intravitreous Ranibizumab for Proliferative Diabetic Retinopathy: A Randomized Clinical Trial
ACS is a common and potentially lethal problem. However, only about 10% of patients who present to an emergency department with chest pain actually have ACS. In this JAMA Clinical Reviews podcast, we discuss which signs, symptoms and tests used to make the diagnosis of ACS are reliable.
Edward H. Livingston MD, speaks with Alexander Fanaroff, MD, author of Does This Patient With Chest Pain Have Acute Coronary Syndrome? The Rational Clinical Examination Systematic Review as well as a patient who was diagnosed with myocardial infarction.
Interview with David Simel, MD, author of Does This Patient With Chest Pain Have Acute Coronary Syndrome? The Rational Clinical Examination Systematic Review
Interview with David A. Asch, MD and Kevin G. Volpp, MD, PhD, authors of Effect of Financial Incentives to Physicians, Patients, or Both on Lipid Levels: A Randomized Clinical Trial
Interview with Elizabeth D. Kantor, PhD, MPH, author of Trends in Prescription Drug Use Among Adults in the United States From 1999-2012
Interview with Ahmedin Jemal, DVM, PhD, author of Temporal Trends in Mortality in the United States, 1969-2013, and J. Michael McGinnis, MD, MPP, author of Mortality Trends and Signs of Health Progress. Also in this episode is a conversation with Christopher J.L. Murray, MD, DPhil, a Professor of Global Health at the University of Washington and Institute Director of the Institute for Health Metrics and Evaluation.
Interview with Ahmedin Jemal, DVM, PhD, author of Temporal Trends in Mortality in the United States, 1969-2013
Interview with Elizabeth T. H. Fontham, MPH, DrPH, author of Breast Cancer Screening for Women at Average Risk: 2015 Guideline Update From the American Cancer Society, Nancy L. Keating, MD, MPH, author of New Guidelines for Breast Cancer Screening in US Women, and Evan R. Myers, MD, MPH, author of Benefits and Harms of Breast Cancer Screening: A Systematic Review
Interview with Kevin C. Oeffinger, MD, author of Breast Cancer Screening for Women at Average Risk: 2015 Guideline Update From the American Cancer Society
Interview with James Fleshman, MD, author of Effect of Laparoscopic-Assisted Resection vs Open Resection of Stage II or III Rectal Cancer on Pathologic Outcomes: The ACOSOG Z6051 Randomized Clinical Trial
Interview with Carlos G. Grijalva, MD, MPH, author of Association Between Hospitalization With Community-Acquired Laboratory-Confirmed Influenza Pneumonia and Prior Receipt of Influenza Vaccination
Interview with Timothy Fendler, MD, MS, author of Alignment of Do-Not-Resuscitate Status With Patients’ Likelihood of Favorable Neurological Survival After In-Hospital Cardiac Arrest
Interview with Jeffrey L. Cummings, MD, ScD, author of Effect of Dextromethorphan-Quinidine on Agitation in Patients With Alzheimer Disease Dementia: A Randomized Clinical Trial
Adi Nadimpalli, MD, the Doctors Without Borders/Médecins Sans Frontières (MSF) Head of Mission in Nepal, and the former vice president of the US board of directors, talks about MSF’s mission and the challenges he has faced serving in countries where access to health care is insufficient or strained due to natural or manmade disasters, violent conflicts, epidemics, and population displacement.
Interview with Anupam Jena, MD, PhD, author of Sex Differences in Academic Rank in US Medical Schools in 2014
Interview with Andy Menke, PhD, author of Prevalence of and Trends in Diabetes Among Adults in the United States, 1988-2012
Interview with Luke Rudmik, MD, MSc, author of Medical Therapies for Adult Chronic Sinusitis: A Systematic Review. This systematic review summarizes the evidence-based medical treatment of adult chronic sinusitis and proposes a treatment algorithm.
Interview with Bridget A. Fernandez, MD, author of Molecular Diagnostic Yield of Chromosomal Microarray Analysis and Whole-Exome Sequencing in Children With Autism Spectrum Disorder
Interview with Timothy Ley, MD, author of Association Between Mutation Clearance After Induction Therapy and Outcomes in Acute Myeloid Leukemia
Interview with Kaycee M. Sink, MD, MAS, author of Effect of a 24-Month Physical Activity Intervention vs Health Education on Cognitive Outcomes in Sedentary Older Adults: The LIFE Randomized Trial
Interview with Nancy A. Rigotti, MD, author of e-Cigarette Use and Subsequent Tobacco Use by Adolescents: New Evidence About a Potential Risk of e-Cigarettes
Interview with Adam M. Leventhal, PhD, author of Association of Electronic Cigarette Use With Initiation of Combustible Tobacco Product Smoking in Early Adolescence
Interview with Rachel E. Patzer, PhD, MPH, author of Variation in Dialysis Facility Referral for Kidney Transplantation Among Patients With End-Stage Renal Disease in Georgia. This population epidemiology study uses United States Renal Data System data to characterize dialysis facility–level referral for kidney transplant evaluation in Georgia, the US state with the lowest transplantation rates, and patient and facility factors associated with referral and waitlisting.
Interview with Shalender Bhasin, MBBS, author of Effects of Testosterone Administration for 3 Years on Subclinical Atherosclerosis Progression in Older Men With Low or Low-Normal Testosterone Levels: A Randomized Clinical Trial
Edward H. Livingston, MD, interviews a war veteran and discusses PTSD with Maria Steenkamp, PhD, author of Psychotherapy for Military-Related PTSD, and Michele Spoont, PhD, author of Rational Clinical Exam: Does This Patient Have Posttraumatic Stress Disorder? The article by Dr Steenkamp reports that many military personnel and veterans with posttraumatic stress disorder achieve clinically meaningful improvement with use of the first-line trauma-focused interventions cognitive processing therapy and prolonged exposure. The Rational Clinical Examination Systematic Review by Dr Spoont examines the utility of self-report screening instruments for posttraumatic stress disorder among primary care and high-risk populations.
Interview with Melissa A. Polusny, PhD, author of Mindfulness-Based Stress Reduction for Posttraumatic Stress Disorder Among Veterans: A Randomized Clinical Trial
Interview with Drew Altman, PhD and William Frist, MD, authors of Medicare and Medicaid at 50 Years: Perspectives of Beneficiaries, Health Care Professionals and Institutions, and Policy Makers
Interview with Harlan M. Krumholz, MD, SM, author of Mortality, Hospitalizations, and Expenditures for the Medicare Population Aged 65 Years or Older, 1999-2013
Edward H. Livingston, MD discusses atrial fibrillation with Eric N. Prystowsky, MD, author of Treatment of Atrial Fibrillation. This review article reports that therapy for atrial fibrillation should include rate control for all patients, but maintenance of sinus rhythm with drugs or catheter ablation should be considered on an individual patient basis. Also on the program is a conversation about new technologies to facilitate screening for atrial fibrillation with Leslie Saxon, MD.
Interview with Carolina Malta Hansen, MD, author of Association of Bystander and First-Responder Intervention With Survival After Out-of-Hospital Cardiac Arrest in North Carolina, 2010-2013
Interview with Thomas A. Gaziano, MD, MSc, author of Cost-effectiveness of 10-Year Risk Thresholds for Initiation of Statin Therapy for Primary Prevention of Cardiovascular Disease
Interview with Diana W. Bianchi, MD, author of Noninvasive Prenatal Testing and Incidental Detection of Occult Maternal Malignancies
Interview with Francis Couturaud, MD, PhD, author of Six Months vs Extended Oral Anticoagulation After a First Episode of Pulmonary Embolism: The PADIS-PE Randomized Clinical Trial
Interview with Deborah A. Levine, MD, MPH, author of Trajectory of Cognitive Decline After Incident Stroke
Harold Varmus, MD, former director of the National Cancer Institute, talks about his career and his ideas for improving the biomedical research enterprise.
Interview with Kevin P. Hill, MD, MHS, author of Medical Marijuana for Treatment of Chronic Pain and Other Medical and Psychiatric Problems: A Clinical Review, and Deepak Cyril D'Souza, MBBS, MD, author of Medical Marijuana: Is the Cart Before the Horse?
Interview with Tracy Y. Wang, MD, MHS, MSc, author of Implantable Cardioverter-Defibrillator Use Among Medicare Patients With Low Ejection Fraction After Acute Myocardial Infarction
JAMA Topic Review: Edward Livingston, MD, FACS, AGAF, Deputy Editor of JAMA, explores how the study by Paulina Salminen, MD, PhD, supports treating appendicitis without surgery
Interview with Chyke A. Doubeni, MD, MPH, author of Variation in Adenoma Detection Rate and the Lifetime Benefits and Cost of Colorectal Cancer Screening: A Microsimulation Model
Interview with Ellen Wright Clayton, MD, JD , author of Why the Americans With Disabilities Act Matters for Genetics
Interview with Samuel R. Bagenstos, JD, author of The ADA and the Supreme Court: A Mixed Record
Interview with Levi J. Hargrove, PhD, author of Intuitive Control of a Powered Prosthetic Leg During Ambulation: A Randomized Clinical Trial
Interview with Patrick H. Conway, MD, MSc, author of Association of Pioneer Accountable Care Organizations vs Traditional Medicare Fee for Service With Spending, Utilization, and Patient Experience
Interview with Krista F. Huybrechts, MS, PhD, author of Antidepressant Use Late in Pregnancy and Risk of Persistent Pulmonary Hypertension of the Newborn
Interview with Anne R. Cappola, MD, ScM, author of Subclinical Thyroid Dysfunction and Fracture Risk: A Meta-analysis
Interview with Harley Goldberg, DO, author of Oral Steroids for Acute Radiculopathy Due to a Herniated Lumbar Disk: A Randomized Clinical Trial
Interview with Andrew J. Muir, MD, author of Daclatasvir in Combination With Asunaprevir and Beclabuvir for Hepatitis C Virus Genotype 1 Infection With Compensated Cirrhosis
Interview with Dale N. Gerding, MD, author of Administration of Spores of Nontoxigenic Clostridium difficile Strain M3 for Prevention of Recurrent C difficile Infection: A Randomized Clinical Trial
Interview with Gail D'Onofrio, MD, MS, author of Emergency Department-Initiated Buprenorphine/Naloxone Treatment for Opioid Dependence: A Randomized Clinical Trial
Interview with Ezio Bonifacio, PhD, author of Effects of High-Dose Oral Insulin on Immune Responses in Children at High Risk for Type 1 Diabetes: The Pre-POINT Randomized Clinical Trial
Interview with Anjali Jain, MD, author of Autism Occurrence by MMR Vaccine Status Among US Children With Older Siblings With and Without Autism
Interview with Anny H. Xiang, PhD, author of Association of Maternal Diabetes With Autism in Offspring
Interview with Justin B. Dimick, MD, MPH, author of Hospital Credentialing and Privileging of Surgeons: A Potential Safety Blind Spot
Interview with Mark J. Mulligan, MD, author of Emergency Postexposure Vaccination With Vesicular Stomatitis Virus-Vectored Ebola Vaccine After Needlestick
Interview with Jeffrey G. Jarvik, MD, MPH, author of Association of Early Imaging for Back Pain With Clinical Outcomes in Older Adults
Interview with Joann G. Elmore, MD, MPH, author of Diagnostic Concordance Among Pathologists Interpreting Breast Biopsy Specimens
Interview with Xiaobin Wang, MD, ScD, author of Efficacy of Folic Acid Therapy in Primary Prevention of Stroke Among Adults With Hypertension in China: The CSPPT Randomized Clinical Trial
Interview with David R. Holmes Jr, MD, author of Clinical Outcomes at 1 Year Following Transcatheter Aortic Valve Replacement
Interview with Sebastiano Filetti, MD, author of The Natural History of Benign Thyroid Nodules
Interview with Vicky Stergiopoulos, MD, author of Effect of Scattered-Site Housing Using Rent Supplements and Intensive Case Management on Housing Stability Among Homeless Adults With Mental Illness
Interview with William E. Evans, PharmD, author of Association of an Inherited Genetic Variant With Vincristine-Related Peripheral Neuropathy in Children With Acute Lymphoblastic Leukemia
Interview with Antoni Torres, MD, PhD, author of Effect of Corticosteroids on Treatment Failure Among Hospitalized Patients With Severe Community-Acquired Pneumonia and High Inflammatory Response: A Randomized Clinical Trial
Interview with Jon O. Ebbert, MD, MSc, author of Effect of Varenicline on Smoking Cessation Through Smoking Reduction
Interview with Joseph E. Kiss, MD, author of Oral Iron Supplementation After Blood Donation
Interview with Donald M. Berwick, MD, MPP, author of Measuring Surgical Outcomes for Improvement: Was Codman Wrong?
Interview with Karl Y. Bilimoria, MD, MS, author of Underlying Reasons Associated With Hospital Readmission Following Surgery in the United States
Interview with Peter A. Pinto, MD, author of Comparison of MR/Ultrasound Fusion-Guided Biopsy With Ultrasound-Guided Biopsy for the Diagnosis of Prostate Cancer
Interview with Richard K. Burt, MD, author of Association of Nonmyeloablative Hematopoietic Stem Cell Transplantation With Neurological Disability in Patients With Relapsing-Remitting Multiple Sclerosis
Interview with Sheree L. Boulet, DrPH, MPH, author of Trends in Use of and Reproductive Outcomes Associated With Intracytoplasmic Sperm Injection
Interview with Steven A. Narod, MD, FRCPC, author of Differences in Breast Cancer Stage at Diagnosis and Cancer-Specific Survival by Race and Ethnicity in the United States
Interview with David E. Arterburn, MD, MPH and Matthew L. Maciejewski, PhD, authors of Association Between Bariatric Surgery and Long-term Survival
Interview with David M. Nathan, MD, author of Association Between 7 Years of Intensive Treatment of Type 1 Diabetes and Long-term Mortality
Interview with Seetha Shankaran, MD, author of Effect of Depth and Duration of Cooling on Deaths in the NICU Among Neonates With Hypoxic Ischemic Encephalopathy: A Randomized Clinical Trial
Tom Frieden, MD, MPH, Director, Centers for Disease Control and Prevention, talks with Howard Bauchner, MD, Editor in Chief of JAMA, about the Ebola crisis and the CDC’s response (originally posted on 10-23-2014).
Dr Aiah A. Gbakima, editor in chief of the Sierra Leone Journal of Biomedical Research, talks about confronting the Ebola outbreak in Sierra Leone (originally posted on 10-2-2014).
Interview with Ricardo A. Mosquera, MD, author of Effect of an Enhanced Medical Home on Serious Illness and Cost of Care Among High-Risk Children With Chronic Illness
Interview with Frank M. Sacks, MD, author of Effects of High vs Low Glycemic Index of Dietary Carbohydrate on Cardiovascular Disease Risk Factors and Insulin Sensitivity
Interview with Bradley M. Gray, PhD, author of Association Between Imposition of a Maintenance of Certification Requirement and Ambulatory Care-Sensitive Hospitalizations and Health Care Costs
Interview with Mitesh S. Patel, MD, MBA, MS, author of Association of the 2011 ACGME Resident Duty Hour Reforms With Mortality and Readmissions Among Hospitalized Medicare Patients
Interview with Joseph B. Muhlestein, MD, author of Effect of Screening for Coronary Artery Disease Using CT Angiography on Mortality and Cardiac Events in High-Risk Patients With Diabetes
Interview with Michelle M. Mello, JD, PhD, MPhil, author of The Medical Liability Climate and Prospects for Reform
Interview with Arthur J. Reynolds, PhD, author of Association of a Full-Day vs Part-Day Preschool Intervention With School Readiness, Attendance, and Parent Involvement
Interview with Stefanie Schulz-Schüpke, MD, author of Comparison of Vascular Closure Devices vs Manual Compression After Femoral Artery Puncture: The ISAR-CLOSURE Randomized Clinical Trial
Interview with George A. Stouffer, MD, author of Association of Inpatient vs Outpatient Onset of ST-Elevation Myocardial Infarction With Treatment and Clinical Outcomes
Interview with Ziad Obermeyer, MD, MPhil, author of Association Between the Medicare Hospice Benefit and Health Care Utilization and Costs for Patients With Poor-Prognosis Cancer
Interview with Ilan Youngster, MD, MMSc, author of Oral, Capsulized, Frozen Fecal Microbiota Transplantation for Relapsing Clostridium difficile Infection
Interview with Thomas M. Maddox, MD, MSc, author of Nonobstructive Coronary Artery Disease and Risk of Myocardial Infarction
Interview with Ashish K. Jha, MD, MPH, author of Association Between Hospital Conversions to For-Profit Status and Clinical and Economic Outcomes
Interview with Jonathan A. Patz, MD, MPH, author of Climate Change: Challenges and Opportunities for Global Health
Interview with Elizabeth A Howell, MD, MPP, author of Durability of Benefits of an Outpatient Antimicrobial Stewardship Intervention After Discontinuation of Audit and Feedback
Interview with Shelley S. Magill, MD, PhD, author of Prevalence of Antimicrobial Use in US Acute Care Hospitals, May-September 2011
Interview with Kim L. Bennell, PhD, author of Acupuncture for Chronic Knee Pain: A Randomized Clinical Trial
Interview with Irfan A. Dhalla, MD, MSc, author of Effect of a Postdischarge Virtual Ward on Readmission or Death for High-Risk Patients
Interview with Miriam Kuppermann, PhD, MPH, author of Effect of Enhanced Information, Values Clarification, and Removal of Financial Barriers on Use of Prenatal Genetic Testing
Interview with Marc Carrier, MD, MSc, author of Clinical and Safety Outcomes Associated With Treatment of Acute Venous Thromboembolism: A Systematic Review and Meta-analysis
Interview with Andrea S. Gershon, MD, MSc, author of Combination Long-Acting β-Agonists and Inhaled Corticosteroids Compared With Long-Acting β-Agonists Alone in Older Adults With Chronic Obstructive Pulmonary Disease
Interview with Bradley C. Johnston, PhD, author of Comparison of Weight Loss Among Named Diet Programs in Overweight and Obese Adults: A Meta-analysis
Interview with Allison W. Kurian, MD, MSc, author of Use of and Mortality After Bilateral Mastectomy Compared With Other Surgical Treatments for Breast Cancer in California, 1998-2011
Interview with Laura P. Richardson, MD, MPH, author of Collaborative Care for Adolescents With Depression in Primary Care
Interview with Harsha Thirumurthy, PhD, author of Effect of Providing Conditional Economic Compensation on Uptake of Voluntary Medical Male Circumcision in Kenya: A Randomized Clinical Trial
Interview with Nancy A. Rigotti, MD, author of Sustained Care Intervention and Postdischarge Smoking Cessation Among Hospitalized Adults
Interview with Hooman Kamel, MD, author of Perioperative Atrial Fibrillation and the Long-term Risk of Ischemic Stroke
Interview with Karen A. D'Silva, MD, MS, author of Does This Man With Lower Urinary Tract Symptoms Have Bladder Outlet Obstruction? The Rational Clinical Examination: A Systematic Review
Interview with Richard Saitz, MD, MPH, author of Screening and Brief Intervention for Drug Use in Primary Care
Interview with Mark S. Sulkowski, MD, author of Sofosbuvir and Ribavirin for Hepatitis C in Patients With HIV Coinfection
Interview with Mads E. Jørgensen, MB, author of Time Elapsed After Ischemic Stroke and Risk of Adverse Cardiovascular Events and Mortality Following Elective Noncardiac Surgery
Interview with Kurt Kroenke, MD, author of Telecare Collaborative Management of Chronic Pain in Primary Care
Interview with Danny Dvir, MD, author of Transcatheter Aortic Valve Implantation in Failed Bioprosthetic Surgical Valves
Interview with Claudia S. Robertson, MD, author of Effect of Erythropoietin and Transfusion Threshold on Neurological Recovery After Traumatic Brain Injury: A Randomized Clinical Trial
Interview with John F. Tisdale, MD, author of Nonmyeloablative HLA-Matched Sibling Allogeneic Hematopoietic Stem Cell Transplantation for Severe Sickle Cell Phenotype
Interview with Sarah M. Friedewald, MD, author of Breast Cancer Screening Using Tomosynthesis in Combination With Digital Mammography
Interview with Nynne Nyboe Andersen, MD, author of Association Between Tumor Necrosis Factor-α Antagonists and Risk of Cancer in Patients With Inflammatory Bowel Disease
Interview with Christianne L. Roumie, MD, MPH, author of Association Between Intensification of Metformin Treatment With Insulin vs Sulfonylureas and Cardiovascular Events and All-Cause Mortality Among Patients With Diabetes
Interview with Rupert M. Pearse, MD, author of Effect of a Perioperative, Cardiac Output-Guided Hemodynamic Therapy Algorithm on Outcomes Following Major Gastrointestinal Surgery: A Randomized Clinical Trial and Systematic Review
Interview with Eric M. Mortensen, MD, MSc, author of Association of Azithromycin With Mortality and Cardiovascular Events Among Older Patients Hospitalized With Pneumonia
Interview with Marco Pahor, MD, author of Effect of Structured Physical Activity on Prevention of Major Mobility Disability in Older Adults: The LIFE Study Randomized Clinical Trial
Interview with Kim L. Bennell, PhD, author of Effect of Physical Therapy on Pain and Function in Patients With Hip Osteoarthritis: A Randomized Clinical Trial
Interview with Mark G. Kris, MD, author of Using Multiplexed Assays of Oncogenic Drivers in Lung Cancers to Select Targeted Drugs
Interview with Mario Castro, MD, author of Effect of Vitamin D3 on Asthma Treatment Failures in Adults With Symptomatic Asthma and Lower Vitamin D Levels
Interview with Larry Wolk, MD, MSPH, chief medical officer for the Colorado Department of Public Health, about medical and legalized marijuana in Colorado.
Interview with Robert N. Weinreb, MD, author of The Pathophysiology and Treatment of Glaucoma
Interview with Dana Dabelea, MD, PhD, author of Prevalence of Type 1 and Type 2 Diabetes Among Children and Adolescents From 2001 to 2009
Interview with Gregg C. Fonarow, MD, author of Door-to-Needle Times for Tissue Plasminogen Activator Administration and Clinical Outcomes in Acute Ischemic Stroke Before and After a Quality Improvement Initiative
Interview with Mohamed Abdel-Wahab, MD, author of Comparison of Balloon-Expandable vs Self-expandable Valves in Patients Undergoing Transcatheter Aortic Valve Replacement: The CHOICE Randomized Clinical Trial
Interview with Louise C. Walter, MD and Mara A. Schonberg, MD, MPH, authors of Screening Mammography in Older Women: A Review
Interview with Nancy L. Keating, MD, MPH, author of A Systematic Assessment of Benefits and Risks to Guide Breast Cancer Screening Decisions
Interview with Ann Marie Navar-Boggan, MD, PhD, author of Proportion of US Adults Potentially Affected by the 2014 Hypertension Guideline
Interview with Nicholas J. Horton, ScD, author of Web-Based Alcohol Screening and Brief Intervention for University Students: A Randomized Trial
Interview with Michael J. Barry, MD, author of Screening for Prostate Cancer With the Prostate-Specific Antigen Test: A Review of Current Evidence
Interview with Derek C. Angus, MD, MPH, author of Psychiatric Diagnoses and Psychoactive Medication Use Among Nonsurgical Critically Ill Patients Receiving Mechanical Ventilation
Interview with Matthew D. Barber, MD, MHS, author of Comparison of 2 Transvaginal Surgical Approaches and Perioperative Behavioral Therapy for Apical Vaginal Prolapse
Interview with Juan Jesús Carrero, PhD(Pharm and Med), author of Warfarin, Kidney Dysfunction, and Outcomes Following Acute Myocardial Infarction in Patients With Atrial Fibrillation
Interview with Ronald C. Kessler, PhD, author of Associations of Housing Mobility Interventions for Children in High-Poverty Neighborhoods With Subsequent Mental Disorders During Adolescence
Interview with Mark W. Friedberg, MD, MPP, author of Association Between Participation in a Multipayer Medical Home Intervention and Changes in Quality, Utilization, and Costs of Care
Interview with Claudia A. Steiner, MD, MPH, author of Surgical Site Infections Following Ambulatory Surgery Procedures
Interview with Constantine G. Lyketsos, MD, MHS, author of Effect of Citalopram on Agitation in Alzheimer Disease
Interview with Lisen Arnheim-Dahlström, PhD, author of Association of Varying Number of Doses of Quadrivalent Human Papillomavirus Vaccine With Incidence of Condyloma
Interview with Troyen A. Brennan, MD, MPH, author of Ending Sales of Tobacco Products in Pharmacies
Interview with Norrina B. Allen, PhD, MPH, author of Blood Pressure Trajectories in Early Adulthood and Subclinical Atherosclerosis in Middle Age
Interview with Joseph S. Ross, MD, MHS, author of Clinical Trial Evidence Supporting FDA Approval of Novel Therapeutic Agents, 2005-2012
Interview with John N. Primrose, MD, FRCS, author of Effect of 3 to 5 Years of Scheduled CEA and CT Follow-up to Detect Recurrence of Colorectal Cancer: The FACS Randomized Clinical Trial
Interview with Michael H. Criqui, MD, MPH, author of Calcium Density of Coronary Artery Plaque and Risk of Incident Cardiovascular Events
Interview with Theodore R. Holford, PhD, author of Tobacco Control and the Reduction in Smoking-Related Premature Deaths in the United States, 1964-2012
Interview with Susan Z. Yanovski, MD, author of Long-term Drug Treatment for Obesity: A Systematic and Clinical Review
Interview with Maurice W. Dysken, MD, author of Effect of Vitamin E and Memantine on Functional Decline in Alzheimer Disease: The TEAM-AD VA Cooperative Randomized Trial
Interview with Scott W. Powers, PhD, author of Cognitive Behavioral Therapy Plus Amitriptyline for Chronic Migraine in Children and Adolescents
Interview with Paul A. James, MD, author of 2014 Evidence-Based Guideline for the Management of High Blood Pressure in Adults: Report From the Panel Members Appointed to the Eighth Joint National Committee (JNC 8)
Interview with Amit X. Garg, MD, PhD, author of Calcium-Channel Blocker-Clarithromycin Drug Interactions and Acute Kidney Injury
Interview with Deepak L. Bhatt, MD, MPH, author of Three vs Twelve Months of Dual Antiplatelet Therapy After Zotarolimus-Eluting Stents
Interview with Anita P. Courcoulas, MD, MPH, author of Weight Change and Health Outcomes at 3 Years After Bariatric Surgery Among Individuals With Severe Obesity
Interview with J. Randall Curtis, MD, MPH, author of Effect of Communication Skills Training for Residents and Nurse Practitioners on Quality of Communication With Patients With Serious Illness: A Randomized Trial
Interview with Amy J. Starmer, MD, MPH, author of Rates of Medical Errors and Preventable Adverse Events Among Hospitalized Children Following Implementation of a Resident Handoff Bundle
Interview with Marianna K Baum, PhD, author of Effect of Micronutrient Supplementation on Disease Progression in Asymptomatic, Antiretroviral-Naive, HIV-Infected Adults in Botswana
Interview with Prashanthan Sanders, MBBS, PhD, author of Effect of Weight Reduction and Cardiometabolic Risk Factor Management on Symptom Burden and Severity in Patients With Atrial Fibrillation: A Randomized Clinical Trial
Interview with Michael J. Mack, MD, author of Outcomes Following Transcatheter Aortic Valve Replacement in the United States
Interview with Hamilton Moses III, MD, author of The Anatomy of Health Care in the United States
Interview with Christopher Vinden, MD, author of Complications of Daytime Elective Laparoscopic Cholecystectomies Performed by Surgeons Who Operated the Night Before
Interview with Michael Ho, MD, PhD, author of Association of Testosterone Therapy With Mortality, Myocardial Infarction, and Stroke in Men With Low Testosterone Levels
Interview with Jacob A. Udell, MD, MPH, FRCPC, author of Association Between Influenza Vaccination and Cardiovascular Outcomes in High-Risk Patients: A Meta-analysis
Howard Bauchner, MD interviews Ramin W. Parsa-Parsi, MD, MPH and Heikki Pälve, MD, PhD about the World Medical Association's Declaration of Helsinki: Ethical Principles for Medical Research Involving Human Subjects
Interview with Björn Pasternak, MD, PhD, author of Metoclopramide in Pregnancy and Risk of Major Congenital Malformations and Fetal Death
Interview with Karl Y. Bilimoria, MD, author of Evaluation of Surveillance Bias and the Validity of the Venous Thromboembolism Quality Measure
Interview with Anthony D. Harris, MD, author of Universal Glove and Gown Use and Acquisition of Antibiotic-Resistant Bacteria in the ICU: A Randomized Trial
Interview with Christian Torp-Pedersen, MD, DSc, author of Association of National Initiatives to Improve Cardiac Arrest Management With Rates of Bystander Intervention and Patient Survival After Out-of-Hospital Cardiac Arrest
Interview with JoAnn E. Manson, MD, author of Menopausal Hormone Therapy and Health Outcomes During the Intervention and Extended Poststopping Phases of the Women's Health Initiative Randomized Trials
Interview with Sarah D. Berry, MD, author of Repeat Bone Mineral Density Screening and Prediction of Hip and Major Osteoporotic Fracture
Interview with Cynthia J. Brown, MD, author of Mobility Limitation in the Older Patient: A Clinical Review
Interview with Richard Saitz, MD, MPH, author of Chronic Care Management for Dependence on Alcohol and Other Drugs
Interview with Laura A. Petersen, MD, MPH, author of Effects of Individual Physician-Level and Practice-Level Financial Incentives on Hypertension Care
Interview with Graeme M. Clark, AC, FRS, FAA, author of The Evolving Science of Cochlear Implants
Interview with Stephen MacMahon, DSc, FMedSci, author of Industry-Sponsored Clinical Trials in Emerging Markets: Time to Review the Terms of Engagement
Interview with Simon Thom, MB,BS, MD, author of Effects of a Fixed-Dose Combination Strategy on Adherence and Risk Factors in Patients With or at High Risk of CVD: The UMPIRE Randomized Clinical Trial
Interview with Anthony S. Fauci, MD, author of Sofosbuvir and Ribavirin for Hepatitis C Genotype 1 in Patients With Unfavorable Treatment Characteristics: A Randomized Clinical Trial
Interview with Neal L. Benowitz, MD, author of The Regulatory Challenge of Electronic Cigarettes
Interview with Marc G. Jaffe, MD, author of Improved Blood Pressure Control Associated With a Large-Scale Hypertension Program
Interview with Edna B. Foa, PhD, author of Concurrent Naltrexone and Prolonged Exposure Therapy for Patients With Comorbid Alcohol Dependence and PTSD: A Randomized Clinical Trial
Interview with Cynthia A. LeardMann, MPH, author of Risk Factors Associated With Suicide in Current and Former US Military Personnel
Interview with Jon C. Tilburt, MD, MPH, author of Views of US Physicians About Controlling Health Care Costs
Interview with Jared P. Reis, PhD, author of Association Between Duration of Overall and Abdominal Obesity Beginning in Young Adulthood and Coronary Artery Calcification in Middle Age
Interview with Wendy M. Chung, MD, SM, author of The 2012 West Nile Encephalitis Epidemic in Dallas, Texas
Interview with Christopher J. L. Murray, MD, DPhil, author of The State of US Health, 1990-2010: Burden of Diseases, Injuries, and Risk Factors
Interview with Daniel D. Matlock, MD, MPH, author of Geographic Variation in Cardiovascular Procedure Use Among Medicare Fee-for-Service vs Medicare Advantage Beneficiaries
Interview with Harvey V. Fineberg, MD, PhD, author of The Paradox of Disease Prevention: Celebrated in Principle, Resisted in Practice
Interview with Karen L. Margolis, MD, MPH, author of Effect of Home Blood Pressure Telemonitoring and Pharmacist Management on Blood Pressure Control: A Cluster Randomized Clinical Trial
Interview with Brent K. Hollenbeck, MD, MS, author of Use of Advanced Treatment Technologies Among Men at Low Risk of Dying From Prostate Cancer
Interview with Jeffrey L. Saver, MD, author of Time to Treatment With Intravenous Tissue Plasminogen Activator and Outcome From Acute Ischemic Stroke
Interview with Anurag N. Malani, MD, author of Magnetic Resonance Imaging Screening to Identify Spinal and Paraspinal Infections Associated With Injections of Contaminated Methylprednisolone Acetate
Interview with Jeffrey S. Gerber, MD, PhD, author of Effect of an Outpatient Antimicrobial Stewardship Intervention on Broad-Spectrum Antibiotic Prescribing by Primary Care Pediatricians: A Randomized Trial
Interview with Jonas Rutishauser, MD, author of Short-term vs Conventional Glucocorticoid Therapy in Acute Exacerbations of Chronic Obstructive Pulmonary Disease: The REDUCE Randomized Clinical Trial
Interview with Sayeed Ikramuddin, MD, author of Roux-en-Y Gastric Bypass vs Intensive Medical Management for the Control of Type 2 Diabetes, Hypertension, and Hyperlipidemia: The Diabetes Surgery Study Randomized Clinical Trial
Interview with Christopher O'Connor, MD, author of Effect of Escitalopram on Mental Stress-Induced Myocardial Ischemia: Results of the REMIT Trial
Interview with Linda Brubaker, MD, author of Long-term Outcomes Following Abdominal Sacrocolpopexy for Pelvic Organ Prolapse
Interview with Emily Y. Chew, MD, author of Lutein + Zeaxanthin and Omega-3 Fatty Acids for Age-Related Macular Degeneration: The Age-Related Eye Disease Study 2 (AREDS2) Randomized Clinical Trial
Interview with Jeffrey Ecker, MD, author of Elective Cesarean Delivery on Maternal Request
Interview with Hope Weiler, RD, PhD, author of Effect of Different Dosages of Oral Vitamin D Supplementation on Vitamin D Status in Healthy, Breastfed Infants: A Randomized Trial
Interview with Simon R. M. Dobson, MD, author of Immunogenicity of 2 Doses of Human Papillomavirus Vaccine in Younger Adolescents Versus 3 Doses in Young Women: A Randomized Clinical Trial
Interview with Jakob Christensen, PhD, author of Prenatal Valproate Exposure and Risk of Autism Spectrum Disorders and Childhood Autism
Interview with Koon Teo, MB, PhD, author of Prevalence of a Healthy Lifestyle Among Individuals With Cardiovascular Disease in High-, Middle- and Low-Income Countries: The Prospective Urban Rural Epidemiology (PURE) Study
Interview with Atul A. Gawande, MD, MPH, author of Relationship Between Occurrence of Surgical Complications and Hospital Finances, and Uwe E. Reinhardt, PhD, author of Making Surgical Complications Pay
Interview with Atul A. Gawande, MD, MPH, author of Relationship Between Occurrence of Surgical Complications and Hospital Finances, and Uwe E. Reinhardt, PhD, author of Making Surgical Complications Pay
Interview with Richard Mayeux, MD, MSc, author of Variants in the ATP-Binding Cassette Transporter (ABCA7), Apolipoprotein E ε4, and the Risk of Late-Onset Alzheimer Disease in African Americans
Interview with Ciaran J. McMullan, MD, author of Melatonin Secretion and the Incidence of Type 2 Diabetes
Interview with Ellen M. Lavoie Smith, PhD, author of Effect of Duloxetine on Pain, Function, and Quality of Life Among Patients With Chemotherapy-Induced Painful Peripheral Neuropathy: A Randomized Clinical Trial
Interview with Gervasio A. Lamas, MD, author of Effect of Disodium EDTA Chelation Regimen on Cardiovascular Events in Patients With Previous Myocardial Infarction: The TACT Randomized Trial
Interview with Frank-Erik de Leeuw, MD, PhD and Loes C. A. Rutten-Jacobs, MSc, authors of Long-term Mortality After Stroke Among Adults Aged 18 to 50 Years
Interview with Maria C. Raven, MD, MPH, MSc, author of Comparison of Presenting Complaint vs Discharge Diagnosis for Identifying "Nonemergency" Emergency Department Visits
Interview with James B. Meigs, MD, MPH, author of Association of Smoking Cessation and Weight Change With Cardiovascular Disease Among People With and Without Diabetes
Interview with Kevin L Winthrop, MD, MPH, author of Association Between the Initiation of Anti-Tumor Necrosis Factor Therapy and the Risk of Herpes Zoster
Interview with Justin B. Dimick, MD, MPH, author of Bariatric Surgery Complications Before vs After Implementation of a National Policy Restricting Coverage to Centers of Excellence
Interview with Jason D. Wright, MD, author of Robotically Assisted vs Laparoscopic Hysterectomy Among Women With Benign Gynecologic Disease
Interview with Pål Surén, author of Association Between Maternal Use of Folic Acid Supplements and Risk of Autism Spectrum Disorders in Children
Interview with Joan M. Teno, MD, MS, author of Change in End-of-Life Care for Medicare Beneficiaries: Site of Death, Place of Care, and Health Care Transitions in 2000, 2005, and 2009
Interview with Harlan M. Krumholz, MD, SM, author of Diagnoses and Timing of 30-Day Readmissions After Hospitalization for Heart Failure, Acute Myocardial Infarction, or Pneumonia
Interview with Daniel S. Chertow, MD, MPH, author of Bacterial Coinfection in Influenza: A Grand Rounds Review
Interview with William H. Shrank, MD, MSHS, author of Association Between Medicare Advantage Plan Star Ratings and Enrollment
Interview with Timothy McAlindon, DM, MPH, author of Effect of Vitamin D Supplementation on Progression of Knee Pain and Cartilage Volume Loss in Patients With Symptomatic Osteoarthritis: A Randomized Controlled Trial
Interview with Victor R. Fuchs, PhD, author of How and Why US Health Care Differs From That in Other OECD Countries
Interview with Katherine M. Flegal, PhD, author of Association of All-Cause Mortality With Overweight and Obesity Using Standard Body Mass Index Categories: A Systematic Review and Meta-analysis
Interview with Bryant J. Webber, MD, author of Prevalence of and Risk Factors for Autopsy-Determined Atherosclerosis Among US Service Members, 2001-2011
Interview with Gilles Montalescot, MD, PhD, author of Association of Clopidogrel Pretreatment With Mortality, Cardiovascular Events, and Major Bleeding Among Patients Undergoing Percutaneous Coronary Intervention: A Systematic Review and Meta-analysis
Interview with Steven D. Stellman, PhD, MPH, author of Association Between World Trade Center Exposure and Excess Cancer Risk
Interview with David S. Friedman, MD, MPH, PhD, author of Prevalence of Nonrefractive Visual Impairment in US Adults and Associated Risk Factors, 1999-2002 and 2005-2008
Interview with Colin P. West, MD, PhD, author of General Medicine vs Subspecialty Career Plans Among Internal Medicine Residents
Interview with Kevin G. Volpp, MD, PhD, author of Effect of a Protected Sleep Period on Hours Slept During Extended Overnight In-hospital Duty Hours Among Medical Interns: A Randomized Trial
Interview with Lara K. Misegades, PhD, MS, author of Association of Childhood Pertussis With Receipt of 5 Doses of Pertussis Vaccine by Time Since Last Vaccine Dose, California, 2010
Interview with Sangeeta Mehta, MD, author of Daily Sedation Interruption in Mechanically Ventilated Critically Ill Patients Cared for With a Sedation Protocol
Interview with Ted E. Palen, MD, PhD, MSPH, author of Association of Online Patient Access to Clinicians and Medical Records With Use of Clinical Services
Interview with Donald M. Lloyd-Jones, MD, ScM, author of Lifetime Risk and Years Lived Free of Total Cardiovascular Disease
Interview with J. Michael Gaziano, MD, MPH, author of Multivitamins in the Prevention of Cardiovascular Disease in Men: The Physicians' Health Study II Randomized Controlled Trial
Interview with Tarak K. Trivedi, BS, author of Hospitalizations and Mortality Associated With Norovirus Outbreaks in Nursing Homes, 2009-2010
Interview with Vineet Chopra, MD, MSc and Scott A Flanders, MD, authors of The Problem With Peripherally Inserted Central Catheters
Interview with Margaret D. Carroll, MSPH, author of Trends in Lipids and Lipoproteins in US Adults, 1988-2010
Interview with Karen E. Joynt, MD, MPH, author of Association of Public Reporting for Percutaneous Coronary Intervention With Utilization and Outcomes Among Medicare Beneficiaries With Acute Myocardial Infarction
Interview with Matthew K. Wynia, MD, MPH, author of Challenges at the Intersection of Team-Based and Patient-Centered Health Care: Insights From an IOM Working Group
Interview with Carlos A. Camargo, MD, author of Effect of Vitamin D3 Supplementation on Upper Respiratory Tract Infections in Healthy Adults: The VIDARIS Randomized Controlled Trial
Interview with Peter Cram, MD, MBA, author of Total Knee Arthroplasty Volume, Utilization, and Outcomes Among Medicare Beneficiaries, 1991-2010
Interview with Griffin P. Rodgers, MD, author of The Next Generation of Obesity Research: No Time to Waste
Interview with Ted D. Adams, PhD, MPH, author of Health Benefits of Gastric Bypass Surgery After 6 Years
Special interview by Howard Bauchner, MD, Editor in Chief of JAMA, with Robert M. Wachter, MD, and Abraham Verghese, MD, MACP, authors of The Attending Physician on the Wards: Finding a New Homeostasis
Interview with William J. Calhoun, MD, author of Comparison of Physician-, Biomarker-, and Symptom-Based Strategies for Adjustment of Inhaled Corticosteroid Therapy in Adults With Asthma: The BASALT Randomized Controlled Trial
Interview with Maria E Suarez-Almazor, MD, PhD, author of Risk of Malignancies in Patients with Rheumatoid Arthritis Treated with Biologic Therapy: A Meta-analysis
Interview with Gary F. Mitchell, MD, author of Aortic Stiffness, Blood Pressure Progression, and Incident Hypertension
Interview with Stephan Windecker, MD, author of Effect of Biolimus-Eluting Stents With Biodegradable Polymer vs Bare-Metal Stents on Cardiovascular Events Among Patients With Acute Myocardial Infarction: The COMFORTABLE AMI Randomized Trial
Interview with Paul Spiegel, MD, author of The State of the World's Refugees: Adapting Health Responses to Urban Environments
Interview with Joanne Klevens, MD, PhD, author of Effect of Screening for Partner Violence on Women's Quality of Life: A Randomized Controlled Trial
Interview with Brian K. Kit, MD, MPH, author of Trends in Serum Lipids Among US Youths Aged 6 to 19 Years, 1988-2010
Interview with James A. Blumenthal, PhD, author of Effects of Exercise Training on Depressive Symptoms in Patients With Chronic Heart Failure: The HF-ACTION Randomized Trial
Interview with Anne L. Coleman, MD, PhD, author of Risk of Fractures Following Cataract Surgery in Medicare Beneficiaries
Interview with Adria Tassy Prosser, PhD, author of HIV in Persons Born Outside the United States, 2007-2010
Interview with Gary S. Kaplan, MD, author of Marshaling Leadership for High-Value Health Care
Interview with Helen Tremlett, PhD, author of Association Between Use of Interferon Beta and Progression of Disability in Patients With Relapsing-Remitting Multiple Sclerosis
Interview with Björn Pasternak, MD, PhD, author of Risk of Adverse Fetal Outcomes Following Administration of a Pandemic Influenza A(H1N1) Vaccine During Pregnancy
Interview with Jeffrey R. Curtis, MD, MS, author of Association Between Vaccination for Herpes Zoster and Risk of Herpes Zoster Infection Among Older Patients With Selected Immune-Mediated Diseases: Herpes Zoster and Immune-Mediated Diseases
Interview with Clinton K. Murray, MD, author of Epidemiology of Staphylococcus aureus Blood and Skin and Soft Tissue Infections in the US Military Health System, 2005-2010
Interview with John M. Jakicic, PhD, author of Effect of a Stepped-Care Intervention Approach on Weight Loss in Adults: A Randomized Clinical Trial
Interview with Emanuele Di Angelantonio, MD, author of Lipid-Related Markers and Cardiovascular Disease Prediction
Interview with Wendy C. King, PhD, author of Prevalence of Alcohol Use Disorders Before and After Bariatric Surgery
Interview with Rebecca Smith-Bindman, MD, author of Use of Diagnostic Imaging Studies and Associated Radiation Exposure for Patients Enrolled in Large Integrated Health Care Systems, 1996-2010
Interview with Victor R. Fuchs, PhD, author of If Accountable Care Organizations Are the Answer, Who Should Create Them?
Interview with David C. Mohr, PhD, author of Effect of Telephone-Administered vs Face-to-face Cognitive Behavioral Therapy on Adherence to Therapy and Depression Outcomes Among Primary Care Patients: A Randomized Trial
Interview with Ferran Barbé, MD, author of Effect of Continuous Positive Airway Pressure on the Incidence of Hypertension and Cardiovascular Events in Nonsleepy Patients With Obstructive Sleep Apnea: A Randomized Controlled Trial
Interview with Jeffrey D. Sachs, PhD, author of Primary Health Care in Low-Income Countries: Building on Recent Achievements
Interview with Eran Bendavid, MD, MS, author of HIV Development Assistance and Adult Mortality in Africa
Interview with Stephen W. Patrick, MD, MPH, MS, author of Neonatal Abstinence Syndrome and Associated Health Care Expenditures: United States, 2000-2009
Interview with Benjamin D. Smith, MD, author of Association Between Treatment With Brachytherapy vs Whole-Breast Irradiation and Subsequent Mastectomy, Complications, and Survival Among Older Women With Invasive Breast Cancer
Interview with Paul A. Offit, MD, author of Studying Complementary and Alternative Therapies
Interview with Eileen T. Lake, PhD, RN, author of Association Between Hospital Recognition for Nursing Excellence and Outcomes of Very Low-Birth-Weight Infants
Interview with Melissa S. Stockwell, MD, MPH, author of Effect of a Text Messaging Intervention on Influenza Vaccination in an Urban, Low-Income Pediatric and Adolescent Population: A Randomized Controlled Trial
Interview with Samuel M. Galvagno Jr, DO, PhD, author of Association Between Helicopter vs Ground Emergency Medical Services and Survival for Adults With Major Trauma
Interview with Donald M. Berwick, MD, MPP, author of Eliminating Waste in US Health Care
Interview with Wendie A. Berg, MD, PhD, author of Detection of Breast Cancer With Addition of Annual Screening Ultrasound or a Single Screening MRI to Mammography in Women With Elevated Breast Cancer Risk
Interview with Dana P. Goldman, PhD, author of Out-of-Pocket Medication Costs and Use of Medications and Health Care Services Among Children With Asthma
Interview with Clifton W. Callaway, MD, PhD, author of Questioning the Use of Epinephrine to Treat Cardiac Arrest
Interview with Soeren Mattke, MD, DSc, author of Utilization of Anesthesia Services During Outpatient Endoscopies and Colonoscopies and Associated Spending in 2003-2009
Interview with Therese A. Stukel, PhD, author of Association of Hospital Spending Intensity With Mortality and Readmission Rates in Ontario Hospitals
Interview with Karen H. Seal, MD, MPH, author of Association of Mental Health Disorders With Prescription Opioids and High-Risk Opioid Use in US Veterans of Iraq and Afghanistan
Interview with John G. Canto, MD, MSPH, author of Association of Age and Sex With Myocardial Infarction Symptom Presentation and In-Hospital Mortality
Interview with Jay F. Piccirillo, MD, author of Amoxicillin for Acute Rhinosinusitis: A Randomized Controlled Trial
Interview with Ulf Ekelund, PhD, author of Moderate to Vigorous Physical Activity and Sedentary Time and Cardiometabolic Risk Factors in Children and Adolescents
Interview with Irene M. Shui, ScD, author of Risk of Intussusception Following Administration of a Pentavalent Rotavirus Vaccine in US Infants
Interview with Laurence E. McCahill, MD, author of Variability in Reexcision Following Breast Conservation Surgery
Interview with Janet T. Holbrook, MPH, PhD, author of Lansoprazole for Children With Poorly Controlled Asthma: A Randomized Controlled Trial
Interview with Eric J. Topol, MD, author of Bridging Antiplatelet Therapy With Cangrelor in Patients Undergoing Cardiac Surgery: A Randomized Controlled Trial
Interview with Frederick P. Rivara, MD, MPH, author of Universal Screening and Drug Treatment of Dyslipidemia in Children and Adolescents
Interview with Stefan Kertesz, MD, author of Association Between Marijuana Exposure and Pulmonary Function Over 20 Years
Interview with George A. Bray, MD, author of Effect of Dietary Protein Content on Weight Gain, Energy Expenditure, and Body Composition During Overeating: A Randomized Controlled Trial
Interview with Ezekiel J. Emanuel, MD, PhD, author of Where Are the Health Care Cost Savings?
Interview with Laurel A. Habel, PhD, author of ADHD Medications and Risk of Serious Cardiovascular Events in Young and Middle-aged Adults
Interview with Roger Chou, MD, author of Prostate Cancer Screening-The Evidence, the Recommendations, and the Clinical Implications
Interview with Charles A. Czeisler, PhD, MD, FRCP, author of Sleep Disorders, Health, and Safety in Police Officers
Interview with Allan S. Detsky, MD, PhD, author of What Patients Really Want From Health Care
Interview with Waldemar A. Carlo, MD, author of Association of Antenatal Corticosteroids With Mortality and Neurodevelopmental Outcomes Among Infants Born at 22 to 25 Weeks' Gestation
Interview with Andrew Wang, MD, author of Association Between Valvular Surgery and Mortality Among Patients With Infective Endocarditis Complicated by Heart Failure
Interview with Martin J. O'Donnell, MB, PhD, author of Urinary Sodium and Potassium Excretion and Risk of Cardiovascular Events
Interview with Jay H. Traverse, MD, author of Effect of Intracoronary Delivery of Autologous Bone Marrow Mononuclear Cells 2 to 3 Weeks Following Acute Myocardial Infarction on Left Ventricular Function: The LateTIME Randomized Trial
Interview with Steven E. Nissen, MD, author of Effects of the CETP Inhibitor Evacetrapib Administered as Monotherapy or in Combination With Statins on HDL and LDL Cholesterol: A Randomized Controlled Trial
Interview with Bimal R. Shah, MD, MB, author of Association Between Physician Billing and Cardiac Stress Testing Patterns Following Coronary Revascularization
Interview with Eric Courchesne, PhD, author of Neuron Number and Size in Prefrontal Cortex of Children With Autism
Interview with Wendy Y. Chen, MD, MPH, author of Moderate Alcohol Consumption During Adult Life, Drinking Patterns, and Breast Cancer Risk
Interview with Pim A. de Jong, MD, PhD, author of Identification of Chronic Obstructive Pulmonary Disease in Lung Cancer Screening Computed Tomographic Scans
Interview with Jersey Chen, MD, MPH, author of National and Regional Trends in Heart Failure Hospitalization and Mortality Rates for Medicare Beneficiaries, 1998-2008
Interview with Mercedeh Kiaii, MD, author of Use of Electron-Beam Sterilized Hemodialysis Membranes and Risk of Thrombocytopenia
Interview with Eric A. Klein, MD, author of Vitamin E and the Risk of Prostate Cancer: The Selenium and Vitamin E Cancer Prevention Trial (SELECT)
Interview with Lauren Hersch Nicholas, PhD, MPP, author of Regional Variation in the Association Between Advance Directives and End-of-Life Medicare Expenditures
Interview with Sunil V. Rao, MD, author of Prevalence and Outcomes of Same-Day Discharge After Elective Percutaneous Coronary Intervention Among Older Patients
Interview with Kevin T. McVary, MD, author of Effect of Increasing Doses of Saw Palmetto Extract on Lower Urinary Tract Symptoms: A Randomized Trial
Interview with Martin E. Franklin, PhD, author of Cognitive Behavior Therapy Augmentation of Pharmacotherapy in Pediatric Obsessive-Compulsive Disorder: The Pediatric OCD Treatment Study II (POTS II) Randomized Controlled Trial
Interview with Martin G. Sanda, MD, author of Prediction of Erectile Function Following Treatment for Prostate Cancer
Interview with Scott V. Masten, PhD, author of Graduated Driver Licensing and Fatal Crashes Involving 16- to 19-Year-Old Drivers
Interview with Colin P. West, MD, PhD, author of Quality of Life, Burnout, Educational Debt, and Medical Knowledge Among Internal Medicine Residents
Interview with Julie A. Freischlag, MD, author of Association of Unconscious Race and Social Class Bias With Vignette-Based Clinical Assessments by Medical Students
Interview with David J. A. Jenkins, MD, author of Effect of a Dietary Portfolio of Cholesterol-Lowering Foods Given at 2 Levels of Intensity of Dietary Advice on Serum Lipids in Hyperlipidemia: A Randomized Controlled Trial
Interview with Megan R. Haymart, MD, author of Use of Radioactive Iodine for Thyroid Cancer
Interview with Stephen M. Shortell, PhD, MPH, MBA, author of Implementing Accountable Care Organizations: Ten Potential Mistakes and How to Learn From Them
Interview with J. Michael McWilliams, MD, Phd, author of Implementation of Medicare Part D and Nondrug Medical Spending for Elderly Adults With Limited Prior Drug Coverage
Interview with Katie L. Stone, PhD, author of Sleep-Disordered Breathing, Hypoxia, and Risk of Mild Cognitive Impairment and Dementia in Older Women
Interview with John H. Krystal, MD, author of Adjunctive Risperidone Treatment for Antidepressant-Resistant Symptoms of Chronic Military Service-Related PTSD
Interview with Charles Hoge, MD, author of Interventions for War-Related Posttraumatic Stress Disorder: Meeting Veterans Where They Are
Interview with June K. Robinson, MD, author of Prevention of Melanoma With Regular Sunscreen Use
Interview with Ryan Radecki, MD, author of Application of Electronic Health Records to the Joint Commission's 2011 National Patient Safety Goals
Interview with Mihai Gheorghiade, MD, author of Improving Postdischarge Outcomes in Patients Hospitalized for Acute Heart Failure Syndromes
Interview with Benjamin Djulbegovic, MD, PhD, author of From Efficacy to Effectiveness in the Face of Uncertainty: Indication Creep and Prevention Creep
Interview with Wendy Levinson, MD, author of Patient-Physican Communication: It's About Time
Interview with David Wendler, PhD, author of How to Enroll Participants in Research Ethically
Interview with Nora D. Volkow, MD, author of Curtailing Diversion and Abuse of Opioid Analgesics Without Jeopardizing Pain Treatment
Interview with Allan S. Detsky, MD, PhD, author of Physician Communication in the 21st Century
Interview with Lawrence O. Gostin, JD, author of Biosafety Concerns Involving Genetically Modified Mosquitoes to Combat Malaria and Dengue in Developing Countries
Interview with Charles Sabatino, JD, author of Damage Prevention and Control for Financial Incapacity
Interview with Peter J. Pronovost, MD, PhD, author of A Physician Management Infrastructure
Interview with Alex H. Krist, MD, MPH, author of A Vision for Patient-Centered Health Information Systems
Interview with Lawrence O. Gostin, JD, author of The United States' Engagement in Global Tobacco Control
Interview with Mark Otto Baerlocher, MD, author of Discussing Radiation Risks Associated With CT Scans With Patients
Interview with Daniel P. Sulmasy, MD, PhD, author of Substituted Interests and Best Judgments: An Integrated Model of Surrogate Decision Making
Interview with Tara Lagu, MD, MPH, author of Putting the Public Back in Public Reporting of Health Care Quality
Interview with Robert H. Brook, MD, ScD, author of What If Physicians Actually Had to Control Medical Costs?
Interview with Laura Weiss Roberts, MD, MA, author of Understanding Depression and Distress Among Medical Students
Interview with Sachin H. Jain, MD, MBA and Christine K. Cassel, MD, authors of Societal Perceptions of Physicians: Knights, Knaves, or Pawns?