Nels and Vincent explain a method to calculate the mutation rate of SARS-CoV-2, and the role of a single amino acid change in spike in enhancing fitness of the delta variant and enabling it to out-compete the alpha variant.

Hosts: Nels Elde and Vincent Racaniello

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Links for this episode * SARS-CoV-2 mutation rate (Genome Biology Evolution) * Delta spike change enhances fitness (bioRxiv) * Time stamps by Jolene. Thanks!

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Vincent – Epidemiological and evolutionary dynamics of SARS-CoV-2

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