🧠 Brain Aging & Research Advances

🔍 Key Findings:

• Brain Age Gap (BAG): Difference between estimated and chronological brain age.

• 64 genes identified as influencing brain aging.

• 13 proteins in blood linked to accelerated/slowed brain aging.

🩺 Potential Interventions:

• 13 anti-aging drugs (e.g., Rapamycin, Dasatinib) show promise in slowing decline.

• Plasma proteomics reveals key biomarkers for early intervention.

🌍 Influencing Factors:

• Socioeconomic status, pollution, and gender inequality impact brain aging.

• Functional connectivity decline linked to cognitive disorders.

🚀 Future Directions:

• Clinical trials needed for drug validation.

• Genetic & proteomic studies should expand to diverse populations.