🧂 Salt sensitivity of blood pressure (SSBP) is an independent risk factor for CVD.

🚹🚺 Women are more salt-sensitive than men, especially after menopause.

⚙️ Key drivers: RAAS, ENaC, natriuresis, and immune pathways.

💉 Estrogen protects, testosterone raises pressure, menopause tips the balance.

🐀 From Dahl’s rats to Conn’s syndrome, SSBP research shows why sex-specific, personalized therapy is the future of hypertension care.

🔗 Nature Reviews Cardiology