🔬🫀 When Troponin Lies: A Case of Macrotroponin 🧪❗

We’ve all seen elevated troponins trigger cath lab calls—but what if the numbers don’t add up? This fascinating case from EHJ Case Reports reveals how an IgG–troponin T complex (macrotroponin) mimicked an acute coronary syndrome in a patient with a structurally normal heart and clean coronaries.

📈 Persistently high cTnT

🧪 Normal cTnI

🧫 Confirmed macrotroponin via SDS-PAGE + immunoblotting

🤝 Biochemistry + Clinical Team = Diagnostic Clarity

This is your reminder: always match the lab to the patient, not the other way around.

🎧 Catch our new podcast episode: “Troponin Trickery: When the Lab Lies, Not the Heart”

#Cardiology #LabMedicine #Troponin #Macrotroponin #Diagnostics #ClinicalPearls #CardiacBiomarkers #Podcast #MedEd #EHJCaseReports