🧬 Can chemical protein aging be reversed? This fascinating study introduces CMLase, an engineered enzyme that removes Nε-carboxymethyl-lysine (CML)—a stable advanced glycation end product (AGE) long believed to be irreversible.

Ex vivo, CMLase repaired AGE damage in aged human lens, skin, and arterial tissues, providing the first proof-of-concept that age-related protein damage may be enzymatically reversible.

While clinical translation remains distant, this work opens an exciting new frontier in regenerative medicine and healthy aging. 🎙️ #Aging #ProteinRepair #RegenerativeMedicine #MedicalPodcasts