🧬 New Nature Medicine review reframes immune aging as a clinical-trial target, not just a biologic curiosity.

The authors propose five criteria for immune-aging biomarkers: immune relevance, temporal association, internal validity, predictive value, and responsiveness.

Key message: move beyond single markers like CRP or IL-6 toward multidimensional, dynamic, standardized measures such as iAge, IMM-AGE, and functional immune-response assays.

The future endpoint may be immune resilience. 🛡️ #Geroscience #Healthspan #Immunology #Biomarkers #MedicalPodcasts