The FRTR Spring 2022 Meeting will explore advances in applying artificial intelligence technologies to site cleanup. Artificial intelligence technologies are beginning to transform how people and machines work together. Robotics and unmanned systems provide opportunities to access dangerous or toxic environments, and improve worker safety. Advances in machine learning are making it possible to process and analyze large data sets in new ways to support remediation decisions. Specific objectives are Review recent technology advances supporting site characterization and remediation.Identify potential benefits, risks and limits of robotics and unmanned aerial systems to support site characterization and remediation.Discuss appropriate use of machine learning and artificial intelligence to support remediation decisions. To view this archive online or download the slides associated with this seminar, please visit http://www.clu-in.org/conf/tio/FRTRSpring22_060622/