Professor Stephen Hawking was a British scientist and was famed for his work with black holes and relativity, and several popular science books including A Brief History of Time.

At the age of 22 Prof Hawking was given only a few years to live after being diagnosed with a rare form of motor neurone disease.

The illness left him in a wheelchair and largely unable to speak except through a voice synthesiser.

Prof Hawking was the first to set out a theory of cosmology as a union of relativity and quantum mechanics.

He also discovered that black holes leak energy and fade to nothing - a phenomenon that would later become known as Hawking radiation.

Through his work with mathematician Sir Roger Penrose he demonstrated that Einstein's general theory of relativity implies space and time would have a beginning in the Big Bang and an end in black holes.

The scientist gained popularity outside the academic world and appeared in several TV shows including The Simpsons, Red Dwarf and The Big Bang Theory.