We're previewing, predicting, and picking (against the spread) the biggest - or at least the most interesting - NFL games coming up in Week 6. Here are the NFL previews and picks we're hitting this week, along with point spreads, over/unders, game time and channel, analytics, and more:

• [1:58] 49ers @ Rams
• [5:38] Lions @ Packers (Monday)
• [8:07] Eagles @ Vikings
• [12:00] Panthers @ Bucs (London)
• [14:30] Texans @ Chiefs
• [20:16] Interesting Games Rapid Fire
• • Saints @ Jags
• • Seahawks @ Browns
• • SNF: Steelers @ Chargers
• • [26:30] Kids make you age faster... so is Phillip Rivers actually older than 38?
• • Giants @ Patriots (Thursday)
• • Redskins @ Dolphins (battle for the #1 pick!)

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