A Crack in Creation: Gene Editing and the Unthinkable Power to Control Evolution

The TWiM hosts reveal how to test antimicrobial susceptibility in less than 30 minutes, and a carbonate-sensitive phytotransferrin in diatoms that controls iron uptake.

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Links for this episode:

  • Legionnaire’s Disease with Michele Swanson
  • Antibiotic susceptibility in less than 30 min (PNAS)
  • S. saprophyticus growing in microfluidic chip (movie, PNAS)
  • Mother machine (Jun lab)
  • E. coli growth in mother machine (YouTube)
  • Diatom phytotransferrin (Nature)
  • CRISPR tool kit (Nat Commun)
  • A Crack in Creation by Doudna and Sternberg
  • CRISPR/Cas9 for undergrads (BMBE)
  • John Oliver on gene editing (YouTube)
  • Image credit
  • Letters read on TWiM 182

Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments to twim@microbe.tv