Today we will begin discussing issues that will lead our young nation War. This war still stands as America’s bloodiest war and is actually a war that is fought internally. North vs. South. Brother vs. Brother. We will specifically identify the causes using the acronym TISSUES and identify how slavery had created instability between a highly agriculture south and a vastly industrial north. I am glad you are here! Sit back, Relax, and let’s Conquer American History.