What is Middle C? Middle C is the 4th C note from the left hand side of a standard 88-key piano (the 5th C from the right hand side) and is commonly tuned to 256 Hz. It is referred to as C4 in scientific pitch notation, is note number 60 in the MIDI protocol and is located on the 1st fret of the 2nd string on a guitar. Middle C sounds like this on a piano: Middle C Note Why is Middle C so important? Middle C is the starting point for many people in their musical journey on a

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