In general, antibiotics as a class potentiate both depolarizing muscular blocking drugs and nondepolarizing neuromuscular blocking drugs to varying degrees. Aminoglycosides have been reported to have a magnesium like effect on the neuromuscular junction. Amphotericin induced hypokalemia has been observed to potentiate. Lincosamides (clindamycin, lincomycin) principal action is direct effect on muscle. Tetracycline administration chelates […]