Hyperkalemic periodic paralysis is an autosomal dominant disease leading to intermittent weakness associated with hyperkalemia and often precipitated by a potassium-rich meal, rest after exercise, or stressful situations. The paralysis lasts up to an hour. Caused (at least partly) by mutations in sodium channel NaV1.4 Cholinesterase inhibitors (ex. neostigmine), depolarizing muscle relaxants (SCh), and potassium can aggravate hyperkalemic periodic […]