Definition Sepsis is an infection-induced syndrome defined as the presence of two or more manifestations of a systemic inflammatory response syndrome (SIRS). SIRS includes: Body temp greater than 38 C or less than 36 C. HR > 90/min. RR> 20/min or PaCO2 < 32mmHg. Leukocytosis (>12×109/L (>12,000/mm³)) or leukopenia (<4×109/L (<4000/mm³)). Mechanical control of ventilation […]