Definition For information on Hypoxic Pulmonic Vasoconstriction, see Hypoxic Pulmonary Vasoconstriction While Hypoxic Pulmonary Vasoconstriction is a well-described phenomena, mammalian lungs may be capable of vasodilating following a hypoxemic challenge (pO2 < 25 mm Hg). It is thought that this response is mediated by adenosine [Gottlieb JE et al. Am J Physiol 247: H541, 1984]. […]