Definition Normal p50 is 27 mm Hg. Several factors can cause a right shift (increased unloading) in the oxyhemoglobin dissociation curve – acidemia, hypercarbia, increased temperature, and increased 2,3-DPG (all of which are more effective during hypoxemia, ex. at tissue levels). Changes in pH and pCO2 generally go hand-in-hand. This is know as the Bohr […]