Definition Carbon monoxide (CO) binds to hemoglobin about 200x tighter than oxygen. This results in Functional anemia (hemoglobin is unavailable for oxygen transport) Decreased oxygen delivery at tissues (left-ward shift of the oxygen-hemoglobin disassociation curve) Carboxyhemoglobin Level Symptoms 1-3% Normal nonsmoker 4-9% Smokers 15-20% Mild signs of toxicity (headache, nausea and vomiting, dizziness, etc.) 20-40% […]