Definition Meperidine is a synthetic opioid widely used for treating pain.  It is also used for controlling post anesthetic shivering. Its main pharmacological action is produced through μ receptors on the central nervous system (CNS). Meperidine is metabolized extensively in the human liver by 1) N-demethylation to normeperidine (6-N-desmethylmeperidine), which may be further hydrolyzed to […]