Definition Acute Treatment Elevating head of bed to improve venous drainage. Oxygenation and ventilation to keep PaO2 >100, PaCO2 30-35, use lowest possible AW pressures to not impede venous drainage, and keep MAP at pre-intubation level. Mannitol decreases blood viscosity, CBF unchanged while CBV and ICP decrease. Mannitol also reduces ICP by reducing cerebral parenchymal […]