Definition Background: Glucagon was originally thought to be a “contaminant” that caused hyperglycemia found in pancreatic extracts in studies from 1923. Looking for the hyperglycemic mechanism of this “contaminant” led to the nobel prize-winning discovery of cyclic adenosine monophosphate (c-AMP) in the 1960s. Full understanding of this hormone did not come until the 1970s, when […]