Volatile Anesthetics Both IV (with the exception of ketamine) and volatile anesthetics reduce CMRO2, however with IV anesthetics there is a concomitant reduction in CBF. Volatile anesthetics, which are vasodilators, do not reduce CBF. In fact, they raise it. Sevoflurane Desflurane Isoflurane N2O CBF + + + + + + CPP – – – – […]