Uterotonics Oxytocin Whereas true oxytocin, which is similar to vasopressin, causes hypertension, synthetic oxytocin (Pitocin) causes hypotension and should be given slowly (ideally ~ 40U in at least 500 cc crystalloid over 10 mins). A bolus of 10U synthetic oxytocin was shown to lower MAP 40%, and SVR 59% (thus cardiac output actually increased), an […]