Nervous System Gin and Chan showed that the median MAC of isoflurane in humans fell 28% during pregnancy (1.075% to 0.775%, p < 0.02) based on Dixon’s up-down method in 20 women (10 per group) [Gin T and Chan MT. Anesthesiology 81: 829, 1994]. They subsequently showed that the MAC of enflurane decreased from 1.65% […]