Commonly caused by antibiotics (PCN causes 95% of fatal reactions), anesthetics, radiocontrast (1:1000 to 1:14,000 injections, 10% of which are fatal [J Crit Illness 8: 332, 1993]), various foods, and insect stings. Presentation can be mild (flushing, rash, urticaria, abdominal cramping, diarrhea) or severe (angioedema, laryngeal edema, bronchospasm, hypotension). Treat with ABCs, 0.3 – 0.5 […]