In this series, Thomas Dayspring, M.D., one of the world's most recognised experts in lipidology, shares his breadth of knowledge on heart disease prevention. Part 1 covers cholesterol, atherosclerosis, production of cholesterol in the brain, lipoprotein classification and much more. This masterclass is perfect for those who cannot attend a lipid and atherosclerosis fellowship.

  • Intro [00:00]
  • Dr Thomas (“Tom”) Dayspring, MD [00:57]
  • Tom’s passion for lipids & perfectionism [03:00]
  • The link between cholesterol & atherosclerosis [13:00]
  • Purpose of cholesterol in the body [14:02]
  • Cholesterol toxicity [15:31]
  • Function & production of lipoproteins [16:18]
  • Foam cells, fatty streaks & plaque progression within the heart [18:41]
  • Ischaemia & myocardial infarction [21:10]
  • Benefits of stopping cholesterol deposition early in life within the artery wall [22:20]
  • Denovo synthesis of lipoproteins [24:10]
  • The brain’s amazing capacity to produce cholesterol [24:50]
  • How the belief that cholesterol is needed for hormone regulation is leading to worse health outcomes in individuals [27:05]
  • Lipoprotein classification [30:00]
  • Outro [36:33]

Give Tom a follow on Twitter: https://twitter.com/Drlipid

Other appearances from Tom: Drive Podcast https://www.youtube.com/watch?v=PllTHYgWpuw

Wellness: Fact vs. Fiction https://podcasts.apple.com/us/podcast/a-masterclass-in-cholesterol-and-lipid-lowering/id1447250475?i=1000581954971

Nutrition Made Simple lp(a): https://www.youtube.com/watch?v=-WRRyG8il4g

Dietary cholesterol: https://www.youtube.com/watch?v=GkWMDnTyxfo

Coronary Calcium Score (CAC): https://www.youtube.com/watch?v=gxIeRUbHauw Narrative glossary on lipids provided by Tom: https://peterattiamd.com/glossary-lipids/

Cholesterol crystallisation: https://pubmed.ncbi.nlm.nih.gov/27332905/

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