There is the common false belief that soy lowers testosterone around the world. In this episode, we dive into soy misinformation with Patrick Elliott, BSc, MPH. Let's learn!

Where to find Patrick Elliott, BSc, MPH:

https://linktr.ee/justhealthinfo

Patrick’s articles for My Nutrition Science:

• https://mynutritionscience.com/misinformation/soy-testosterone/
• https://mynutritionscience.com/misinformation/alkalinecancer/

Patrick’s articles for Training121:

• https://www.training121.com/post/can-vegans-match-omnivores-for-muscle-gains
• https://www.training121.com/post/spotting-nutribollocks-online

Patrick’s research:

• https://pubmed.ncbi.nlm.nih.gov/35452873/
• https://www.mdpi.com/2072-6643/14/24/5371

00:00 Intro | Patrick Elliott, BSc, MPH02:15 Why is soy relevant ?08:15 Soy & Breast Cancer12:18 Equol Producers16:17 Androgenic Hormones19:55 Oestradiol and Oestrone21:22 Does soy decrease testosterone?27:14 Does soy increase oestrogen?29:25 Other sources of plant based protein33:31 The limitations of the studies that support the claim37:02 Tofu 39:10 Outro

References:

Meta-analyses of lower likelihood of breast cancer for higher soy food/isoflavone intake:

2008 paper:

1.https://pubmed.ncbi.nlm.nih.gov/18182974/

2013 paper:

1. https://pubmed.ncbi.nlm.nih.gov/21113655/

2014 paper:

1. https://ncbi.nlm.nih.gov/pmc/articles/PMC3930722/pdf/pone.0089288.pdf

2019 paper (see Fig 3 for RR of 0.87):

4.https://reader.elsevier.com/reader/sd/pii/S0261561417314267?token=B71E40C2889BC54D3322BD5B2DE6D8A0641DB92C63BF7C58CD2B8FD6F13880FC4333CBF32DCD80C6F18742A94F056C94&originRegion=eu-west-1&originCreation=20230421123344

Equol

1. ​​https://pubmed.ncbi.nlm.nih.gov/21092366/

2. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4548170/

7.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5188409/#:~:text=Each%20gram%20of%20soy%20protein,provides%20about%2025%20mg%20isoflavones

8.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5136390/#:~:text=Sex%20Hormone%20Binding%20Globulin%20(SHBG)%20is%20the%20major%20sex%20hormone,free%20%5B1%2C%202%5D.

1. https://www.sciencedirect.com/science/article/pii/S0302283818305463?via%3Dihub

Couple of case-reports

1. https://www.sciencedir ect.com/science/article/abs/pii/S1530891X20433038

11.https://www.sciencedirect.com/science/article/abs/pii/S089990071000359X

Meta-analysis on soy & testosterone

12..https://www.sciencedirect.com/science/article/pii/S0890623820302926?via%3Dihub

Meta-analysis on soy & oestrogen

13.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2691652/pdf/dmp010.pdf

Umbrella Review (Soy and Isoflavone Consumption and Multiple Health Outcomes)

14.. https://pubmed.ncbi.nlm.nih.gov/31584249/

Quorn Study

1. https://pubmed.ncbi.nlm.nih.gov/36822394/

Limitations of the small studies that appear to support the claim

1. https://pubmed.ncbi.nlm.nih.gov/17416779/

2. https://www.nature.com/articles/1601495

Images:

• https://www.ahajournals.org/doi/10.1161/STROKEAHA.120.032042
• https://www.mdpi.com/2072-6643/11/9/2231

More about phytoestrogens:

https://www.sciencedirect.com/science/article/abs/pii/B978012811410000060X

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