Regulatory T cells are an incredibly important part of a healthy immune system. Many of the chronic diseases that we face including, autoimmune diseases, require modification of the immune system in order to support healing. In today’s episode we discuss various pharmacological and natural methods that have been shown to regulate Tregs production and function.

Research DiscussedMedical treatment can unintentionally alter the Treg compartment in patients with widespread pathophysiologic conditions https://ajp.amjpathol.org/article/S0002-9440(20)30369-2/fulltext

The role of vitamin D in increasing circulating T regulatory cell numbers and modulating T regulatory cell phenotypes in patients with inflammatory disease or in healthy volunteers: A systematic review

https://pubmed.ncbi.nlm.nih.gov/31550254/

Metformin reduces autoimmune antibody levels in patients with Hashimoto's thyroiditis: A systematic review and meta-analysis

https://pubmed.ncbi.nlm.nih.gov/32741222/

Promotion of regulatory T cell induction by immunomodulatory herbal medicine licorice and its two constituents

https://www.nature.com/articles/srep14046

Anti-inflammatory effects of the neurotransmitter agonist Honokiol in a mouse model of allergic asthma

https://pubmed.ncbi.nlm.nih.gov/20889543/

Modulation of Immune Function by Polyphenols: Possible Contribution of Epigenetic Factors

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3738975/

N‐acetylcysteine reduces disease activity by blocking mammalian target of rapamycin in T cells from systemic lupus erythematosus patients: A randomized, double‐blind, placebo‐controlled trial†

https://onlinelibrary.wiley.com/doi/full/10.1002/art.34502

Immune Responses Regulated by Cannabidiol

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7173676/

Influence of Dietary Components on Regulatory T Cells

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276397/

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