The first time I heard this question answered was from Amazon's CEO Jeff Bezos.

Jeff was on stage at a press event, and a reporter asked him, "Jeff, what do you think is going to change most in the next 10 years?"

Jeff replied, "That's a good question. But a better question is: What's not going to change in the next 10-20 years?"

He went on to say that, from his perspective at Amazon, what won't change is people's desire for lower prices and faster delivery.

Accordingly, Jeff built Amazon to focus on and invest billions into figuring out how to lower prices and increase the speed with which items are shipped to you.

"When you have something that you know is true," says Jeff, "even over the long term, you can afford to put a lot of energy into it."

WHAT ELSE WON'T CHANGE? My friend Tony Robbins often speaks about the six fundamental human needs.

My guess is that these too will remain constant as long as we humans retain our current neurochemistry.

The six basic human needs include:

1. Certainty: We need assurance that we can avoid pain and gain pleasure

2. Uncertainty/Variety: We have a need for variety, continuous change, and stimulus

3. Significance: We have a need to feel unique, important, and special

4. Connection/Love: We need a strong feeling of connection with people and we need to feel loved

5. Growth: We need to expand each of our own capabilities and capacities

6. Contribution: We need to contribute, and we need a sense of service and focus on giving back.

I’d also add a 7th to this list:

1. The individual’s desire for more freedom: We will constantly be looking for ways to achieve more freedom in our lives. One great example of this is the shift that’s happening in freelance work. From designers on 99Designs to Uber drivers to independent consultants, more and more people are choosing “freelance” career paths because doing so affords them freedom of time, location and association.

While these needs will remain constant, the way we fulfill them will change.

For entrepreneurs, to the extent that you can make achieving these basic needs easier or more fulfilling, people will preferentially adopt your approach.