Ned Landau joins the TWiV team to discuss restriction of HIV replication by SAMHD1, and a viral antagonist that can be used to produce a dendritic cell vaccine.

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Brianne Barker

Guest: Ned Landau

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Links for this episode * Support Viruses Gordon Conference * TWiV #124 September 2008 * SAMHD1 restricts HIV-1 replication (Nature) * SAMHD1 restricts diverse retroviruses (Retrovirology) * Vpx degradation of SAMHD1 independent of uncoating (J Virol) * Transduction of myeloid cells with Vpx vector (Gene Ther) * Letters read on TWiV 511 * Timestamps by Jolene. Thanks!

Weekly Science Picks Brianne- Online Immunology Course
Alan- Bacteria Builder
Rich- 2018 Ig Nobel Prizes
Dickson- Between Fear and Hope
Ned - HUSH silencing of transposons
Vincent - Paywall publishing ban (Schlitz statement); Curry on DORA

Listener Pick Steve- Paywall: Business of Scholarship and Biohazard
Islam- Peer review Twitter post

Intro music is by Ronald Jenkees.

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