TWiV explains how vaccine-induced thrombotic thrombocytopenia develops from antibodies to adenovirus and somatic hypermutation, and castration by a viral protein tyrosine phosphatase that targets a host cell cycle checkpoint protein.

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Brianne Barker Subscribe (free): Apple Podcasts, RSS, email

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Links for this episode * Support science education at MicrobeTV * Positions in Rosenfeld Lab (email) * US repeals environmental endangerment finding (Nature) * Environmental groups sue EPA (Guardian) * NIAID to drop pandemic preparedness and biodefense (Nature) * FDA backpedals on Moderna mRNA rejection (npr) * Mechanism of VITT (NEJM) * Parasitc castration by a wasp virus protein (PNAS) * Polydnaviruses (PloS Path) * Timestamps by Jolene Ramsey. Thanks!

Weekly Picks Brianne – The effect of seeing scientists as intellectually humble on trust in scientists and their research Rich – The Great Bridge: The Epic Story of the Building of the Brooklyn Bridge by David McCullough Alan – Recipes from the American South, by Michael Twitty Vincent – Why Returning From Mars ls Impossible – Richard Feynman’s Warning Intro music is by Ronald Jenkees

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Content in this podcast should not be construed as medical advice.