Listen to the list of the 10 most-viewed papers on Aging-US.com of 2021.

10 - “Iron: an underrated factor in aging” DOI - https://doi.org/10.18632/aging.203612

9 - “Reversal of cognitive decline: A novel therapeutic program” https://doi.org/10.18632/aging.100690

8 - “Shorter telomere lengths in patients with severe COVID-19 disease” https://doi.org/10.18632/aging.202463

7 - “Hyperbaric oxygen therapy alleviates vascular dysfunction and amyloid burden in an Alzheimer’s disease mouse model and in elderly patients” https://doi.org/10.18632/aging.203485

6 - “Fighting the storm: could novel anti-TNFα and anti-IL-6 C. sativa cultivars tame cytokine storm in COVID-19?” https://doi.org/10.18632/aging.202500

5 - “Examining sleep deficiency and disturbance and their risk for incident dementia and all-cause mortality in older adults across 5 years in the United States” https://doi.org/10.18632/aging.202591

4 - “Rejuvant®, a potential life-extending compound formulation with alpha-ketoglutarate and vitamins, conferred an average 8 year reduction in biological aging, after an average of 7 months of use, in the TruAge DNA methylation test” https://doi.org/10.18632/aging.203736

3 - “Aging and rejuvenation - a modular epigenome model” https://doi.org/10.18632/aging.202712

2 - “Potential reversal of epigenetic age using a diet and lifestyle intervention: a pilot randomized clinical trial” https://doi.org/10.18632/aging.202913

1 - “Hyperbaric oxygen therapy increases telomere length and decreases immunosenescence in isolated blood cells: a prospective trial” https://doi.org/10.18632/aging.202188

Keywords - aging, science, research, longevity, lifespan, healthspan, openaccess, researchpapers, journalpublication

About Aging-US

Launched in 2009, Aging-US publishes papers of general interest and biological significance in all fields of aging research and age-related diseases, including cancer—and now, with a special focus on COVID-19 vulnerability as an age-dependent syndrome. Topics in Aging-US go beyond traditional gerontology, including, but not limited to, cellular and molecular biology, human age-related diseases, pathology in model organisms, signal transduction pathways (e.g., p53, sirtuins, and PI-3K/AKT/mTOR, among others), and approaches to modulating these signaling pathways.

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