Chris Mason is a professor of Genomics, Physiology, and Biophysics at Weill Cornell Medicine. He is also one of the founding Directors of the WorldQuant Initiative for Quantitative Prediction.

He is the author of The Next 500 Years: Engineering Life to Reach New Worlds, and the co-author of The Age of Prediction: Algorithms, AI, and the Shifting Shadows of Risk.

0:00 - Intro2:29 - How Long Will Humanity Last?9:01 - On Societal Pessimism and Long-Term Thinking13:02 - Aliens!17:36 - The NASA Twins Study23:17 - Nature vs Nurture25:56 - Chris’ Dream Experiments27:45 - Genomics: Ethics, Opportunities, and the Future37:38 - Space Race 2.0: Colonization, Regulation and Planetary Liberty40:36 - Colonizing Mars and Achieving Planetary Liberty45:46 - The Extreme Microbiome Project47:14 - The Earth Similarity Index, Generation Ships and Leaving the Solar System53:10 - Why Do Any of This in The First Place?56:19 - The Age of Prediction1:01:19 - On Chris, Science, Academia, and Big Questions1:08:47 - Synthetic Biology, Cyborgs and the Future of Human Life1:10:10 - Chris’ Biggest Goal1:11:06 - What Should More People Be Thinking About?

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