A recent study evaluated the role of metformin in causing birth defects, but when the men are prescribed metformin. This obstetrics study evaluates the role of the partner in risk for birth defects. Does the study change practice? Listen as host Geoff Wall discusses how pregnancy involves both partners.
The GameChangerEmerging data suggest that male metformin use during sperm development may increase the risk of birth defects, specifically among baby boys.
Show Segments00:00 - Introduction
01:23 - Metformin Use in Males & Birth Defects
12:29 - The GameChanger
17:29 - Discussing Risk with Patients
19:39 - Closing Remarks
HostGeoff Wall, PharmD., BCPS, FCCP, CGP
Professor of Pharmacy Practice, Drake University
Internal Medicine/Critical Care, UnityPoint Health
All relevant financial relationships have been mitigated.
References and Resources
Preconception Antidiabetic Drugs in Men and Birth Defects in Offspring: A Nationwide Cohort Study
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CE Information
Learning Objectives
1. Describe the design for a population health study using a national database
2. Discuss what type of birth defects were associated with male metformin use in the study
0.05 CEU/0.5 Hr
UAN: 0107-0000-22-213-H01-P
Initial release date: 05/16/2022
Expiration date: 05/16/2023
Additional CPE and CME details can be found here.