Download the cheat: https://bit.ly/50-meds  View the lesson:     Generic Name ondansetron Trade Name Zofran

Indication nausea/vomiting

Action blocks effects of serotonin on vagal nerve and CNS

Therapeutic Class antiemetic

Pharmacologic Class 5-HT3 antagonist

Nursing Considerations • administer slowly over 2-5 minutes – fatal QT prolongation and VTach, respiratory arrest • may cause headache, constipation, diarrhea, dry mouth • asses nausea and vomiting • assess for extrapyramidal symptoms • monitor liver function tests