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Generic Name Captopril

Trade Name Capoten

Indication Hypertension, management of CHF, decrease progression of DM neuropathy

Action Block conversion of angiotensin I to angiotensin II, increases renin levels and decreases aldosterone leading to vasodilation

Therapeutic Class Antihypertensives

Pharmacologic Class ACE Inhibitor

Nursing Considerations • Can cause neutropenia – check WBCs regularly • Use cautiously with potassium supplements and potassium sparing diuretics • Use cautiously with diuretic therapy • Administer 1 hour before meals • Monitor blood pressure often • Monitor weight and fluid status • Monitor renal profile • Monitor CBC frequently • May lead to Rhabdomyolysis • Dry cough