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Generic Name Clopidogrel

Trade Name Plavix

Indication Atherosclerotic events, MI, CVA, PVD, acute coronary syndrome

Action Inhibits platelet aggregation

Therapeutic Class Antiplatelet agent

Pharmacologic Class Platelet aggregation inhibitors

Nursing Considerations • May cause GI bleeding, neutropenia, hypercholesterolemia • May increase risk for bleeding in warfarin, aspirin, heparin • Can increase risk for bleeding with garlic, ginkgo, ginger • Monitor for signs of bleeding • Monitor bleeding times • Monitor CBC and platelet count • Discontinue use 5-7 days before surgery