“Everything is in the hands of G-d, except for the fear of G-d.” – Berachos 33b

Yiras H’Shem (fear of G-d) is a major component of one’s relationship to G-d; fear, in the sense of awe, reverence, and respect. The quality of yiras H’Shem is what will determine the level of kedushah (holiness) in a person’s life.