In this episode, Greg and Rob cover a couple of hot topics in the 340B community. First, they will discuss the recently published HRSA notice regarding a 340B Rebate Model Pilot Program, which is set to initiate in January 2027. They discuss what the operational changes might look like for covered entities, and identify key upcoming dates in HRSA’s implementation timeline. Then, they discuss the recently introduced SENTATE 340B Act, a bipartisan Senate bill that addresses extensive 340B Program reforms. They debate the merits of various provisions in the bill from the perspective of the covered entity, and share opinions on how this might advance through the legislative process.

HRSA Notice Regarding 340B Rebate Model Pilot Program: https://public-inspection.federalregister.gov/2026-15633.pdf

List of Drugs Subject to 340B Rebate Model: 340B Rebate 2026 Chart.pdf

SUSTAIN 340B Act: https://www.moran.senate.gov/public/_cache/files/1/6/169a3bd3-466d-43ee-a15a-2d1f7a3506ca/56EA0919A4EEBD88A3E23AF3E1F6ED76A051C57C7E9B30FB4D1CC9E15FC3FE32.340b.pdf

Questions, comments? Email us at 340BUnscripted@spendmend.com