This is a discussion on the use of early, peripheral vasopressors in patients with septic shock.

The core messages:

- limit fluids

• use vasopressors earlier / synergistically with IV fluids

• Use Noradrenaline

• use it peripherally (ie. through a good, watched, flowing IVC - idealaly proxiaml to the elbow.

• think about the use of CVCs and potential harms / benefits in small hospitals.