The little San Francisco brewery that could has come of age and is celebrating its 21st year. One of the early innovators, 21st Amendment helped put San Francisco on the brewery map. Check the website for special brews and happenings at their venues in San Francisco and San Leandro. They're open Sunday to Wednesday from 11:30 a.m. to 7 p.m. and Thursday to Saturday from 11:30 a.m. to 9 p.m.