Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2022.10.28.514245v1?rss=1

Authors: Rakesh, M., Vezina, H., Laprise, C., Freeman, E., Burkett, K., Roy-Gagnon, M.-H.

Abstract: Summary Founder populations with deep genealogical data are well suited for investigating genetic variants contributing to diseases. Here, we present a new function added to the genealogical analysis R package GENLIB, which can simulate the transmission of haplotypes from founders to probands along very large and complex user-specified genealogies. Availability and implementation The new function is available in the latest version of the GENLIB package (v1.1.6), available on the CRAN repository and from https://github.com/R-GENLIB/GENLIB. Stand-alone scripts for analyzing the output of the function can be accessed at https://github.com/R-GENLIB/simuhaplo_scripts.

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