In this episode of the Oncology Brothers podcast, we are joined by esteemed hematologists Dr. Onyee Chan from Moffitt Cancer Center and Dr. Fadi Haddad from MD Anderson to discuss the management of side effects associated with tyrosine kinase inhibitors (TKIs) used in the treatment of chronic myeloid leukemia (CML).

Join us as we delve into:

  • An overview of the different generations of TKIs, including imatinib, dasatinib, nilotinib, bosutinib, ponatinib, and asciminib.
  • Common class-wide toxicities such as fatigue, hypertension, gastrointestinal symptoms, and cytopenias.
  • Unique side effects associated with each TKI and strategies for dose optimization.
  • The importance of patient education and monitoring to ensure effective management of side effects.

Don't forget to check out our other ToxCheck episodes on antibody drug conjugates, CAR-T therapies, and more!

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