Today, my guest is Dr. Matt Kaeberlein, a CEO of Optispan, anti-aging researcher, Professor at the University of Washington, and founding Director of the University of Washington Healthy Aging and Longevity Research Institute. Dr Kaeberlein is the author of over 250 published scientific research articles on aging, healthspan, and longevity of people and companion animals. Dr. Kaeberlein is a Fellow of the American Association for the Advancement of Science, the American Aging Association, and the Gerontological Society of America. He has received numerous prestigious awards from organizations such as the Alzheimer’s Association and the National Institutes of Health. He has co-founded two companies, Ora Biomedical, Inc., a leading longevity drug discovery biotech, and Optispan, Inc., a healthcare technology company focused on developing innovative tools for 21st-century medicine. He is also the Co-Founder of the Dog Aging Project and Dog Aging Institute.In this episode, Dr Kaeberlein explains the science and practice of nutrition and longevity. We cover animal and human research on nutrition and anti aging. We discuss calorie restriction, intermittent fasting, time-restricted eating, keto diet (ketogenic diet), protein, Mediterranean diet, and the carnivore diet. We also discuss mechanisms of aging and the most convincing human evidence for nutrition and longevity. Finally, Dr Kaeberlein gives tips and tools for everyday anti aging. We also discuss anti aging in dogs (Dog Aging Project).------------------------------------------------------SUBSCRIBE TOSpotify: https://shorturl.at/wAKM2iTunes: https://podcasts.apple.com/ee/podcast/inka-land-podcast/id1654391974------------------------------------------------------SIGN UP / FOLLOWNewsletter: https://www.inkaland.co/newsletterInstagram: https://www.instagram.com/iaminkaland/Subscribe: https://www.youtube.com/@iaminkaland?sub_confirmation=1------------------------------------------------------DR MATT KAEBERLEIN LINKS Website: https://www.optispan.life/YouTube: https://www.youtube.com/@optispanX: https://x.com/mkaeberleinDog Aging Project: https://dogagingproject.org/------------------------------------------------------DISCLAIMERhttps://www.inkaland.co/disclaimer------------------------------------------------------TIMESTAMPS00:00 Intro00:00:25 Anti Aging Trends00:04:00 Anti aging, longevity, and healthspan00:11:50 Healthspan and Biology of Aging00:13:27 Healthspan and Biology of Aging00:14:35 Health in Organs00:15:50 NAD, Health Decline, and Optimal Age for Anti aging00:17:40 Reversing Aging Damage00:19:20 Anti Aging Nutrition Research 00:21:10 Caloric Restriction, Calorie Restriction, and Protein Restriction00:26:00 Risks of Extrapolating and Inflammation00:28:30 Caloric Restriction, Reproduction and Hormonal Health00:32:00 Can Ketogenic Diet Increase Lifespan00:32:50 Genes, Keto diet and Health Benefits00:35:20 Tool: Blood Test, Labs, DEXA, Vo2max, etc00:37:15 Biological Age Tests00:38:20 Human Nutritional Strategies for Anti Aging (Anti Aging diet)00:39:00 Non-Diet Factors00:39:40 Sugar, Protein, Continuous Glucose Monitoring, Processed Foods00:41:20 Mediterranean Diet, MIND Diet, Alzheimer’s Disease00:42:45 Alcohol00:43:21 Extreme Diet and Carnivore Diet00:44:45 Inflammation, Food Intolerance, Immunity, Allergy and Aging00:50:00 Biological Mechanisms of Aging00:53:00 IGF-1, mTOR, and cancer00:54:40 mTOR and Rapamycin, FGF2100:58:30 Dr. Matt Kaeberlein Longevity Protocol01:04:00 Anti Aging in Dogs: Dog Aging Project