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Patients regularly taking famotidine, sold as Pepcid, along with aspirin were 45% less likely to die with CoVid infections severe enough to require ICU-level therapy.  Researchers at the University of Virginia, collaborating with colleagues at Germany’s University of Berlin studied 1578 patients with severe CoVid.

The Pepcid alone reduced mortality 27% while aspirin alone reduced it 21%.  The investigators speculate that Pepcid and aspirin, both anti-inflammatory agents, help CoVid patients by squelching their deadly viral-induced cytokine storm.

This and other studies showing the therapeutic value of famotidine now trigger larger prospective trials.  The researchers suggest that aspirin should also be added to test a Pepcid cocktail.

https://www.medrxiv.org/content/10.1101/2021.03.29.21253914v1.full.pdf+html

#CoVid #icu #famotidine #pepcid #aspirin