Neuro Podcases: Recent Episodes
Neuro Podcases
In this episode with are joined by Mr Nick Carleton-Bland to discuss some of the essential cranial Neurosurgery topics relevant to the UK Medical Licensing exam (MLA).
In episode seven of our Neuroscience Research series, Filippo Dall'Armellina and Dr. Michael Cearns speak with Dr. Nicoletta Landsberger from the University of Milan. Her research focuses on Rett syndrome: a rare, severe X-linked neurodevelopmental disorder and a leading cause of intellectual disability in females. They discuss how the disease progresses in Mecp2-deficient mice, the therapeutic potential of neural precursor cell transplants, and a promising non-invasive treatment strategy: intranasal delivery of nerve growth factor.Research Highlights from the Episode:- Paper 1: Carli et al. A comprehensive longitudinal study of magnetic resonance imaging identifies novel features of the Mecp2-deficient mouse brain. Neurobiology of Disease, 2023. PMID: 36931532.- Paper 2: Frasca et al. Neural precursor cells rescue symptoms of Rett syndrome by activation of the Interferon Ī³ pathway. EMBO, 2024. PMID: 39496971.- Paper 3: Pozzer et al. Clinical-grade intranasal NGF fuels neurological and metabolic functions of Mecp2-deficient mice. Brain, 2025. PMID: 39300821.š§ #NeuroscienceResearchX/Twitter: @NPodcasesVisit the Neuro Podcases website: neuropodcases.co.uk
In this episode of our Neuroscience Research series, Filippo Dall'Armellina and Dr Michael Cearns speak with Professor Julie Williams (Cardiff University), a leading figure in the genetics of Alzheimerās disease. Prof. Williams also co-hosts āIn Two Mindsā with Justine Pickering, so be sure to check it out.Research highlights:- Paper 1: Harold D et al. (2009). Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimerās disease. Nature Genetics. [PMID: 19734902].- Paper 2: Sims R et al. (2017). Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimerās disease. Nature Genetics. [PMID: 28714976].
In this episode of our Neuroscience Research series, hosts Filippo Dall'Armellina and Michael Cearns welcome Professor Adrian Isaacs (UCL), who investigates the molecular and cellular mechanisms underlying FTD and ALS. Research Highlights:- Paper 1: Mizielinska S, et al. C9orf72 repeat expansions cause neurodegeneration in Drosophila through arginine-rich proteins. Science, 2014. [PMID: 25103406] - Paper 2: Kempthorne L, et al. Dual-targeting CRISPR-CasRx reduces C9orf72 ALS/FTD sense and antisense repeat RNAs in vitro and in vivo. Nat Commun., 2025. [PMID: 39779704] - Paper 3: Giblin A, et al. Neuronal polyunsaturated fatty acids are protective in ALS/FTD. Nat Neurosci., 2025. [PMID: 40000803]
In this episode we are joined by Dr Ingrid Hoeritzauer to discuss her approach to the diagnosis and management of functional neurological disorders.
In the fourth episode of our Neuroscience Research series, hosts Filippo Dall'Armellina and Dr. Michael Cearns are joined by Prof. Michele Jacob, Professor of Neuroscience at Tufts University. Prof. Jacobās research focuses on autism spectrum disorders, intellectual disabilities, and the molecular mechanisms underlying neurodevelopmental disorders. Her work spans basic biology, including the Wnt/Ī²-catenin signalling pathway, as well as electrophysiological studies and preclinical mouse models. Together, we discuss groundbreaking evidence for therapeutic interventions targeting conditions such as autism spectrum disorder and the rare CTNNB1 syndrome. Research Highlights from the Episode:- Paper 1: Alexander JM, et al. Excessive Ī²-Catenin in Excitatory Neurons Results in Reduced Social and Increased Repetitive Behaviors and Altered Expression of Multiple Genes Linked to Human Autism. Front Synaptic Neurosci. 2020 Mar 31; PMID: 32296324. - Paper 2: Alexander JM, et al. Inhibition of GSK3Ī±,Ī² Rescues Cognitive Phenotypes in a Preclinical Mouse Model of CTNNB1 Syndrome. EMBO Mol Med. 2024 Sep; PMID: 39103699. š§ #NeuroscienceResearch X/Twitter: @NPodcases Visit the Neuro Podcases website: neuropodcases.co.uk
In this episode of our Neuroscience Research series, hosts Filippo Dall'Armellina and Dr. Michael Cearns engage in a fascinating conversation with Professor Ben Michael, Director of TheĀ BrainĀ Infection & Inflammation Group at the University of Liverpool. Together, they delve into the emerging field of neuro-COVID and Covid-19 associated neurological complications, exploring the ongoing research and the challenges of understanding this novel and complex topic.Research Highlights:- Needham EJ, et al. Brain injury in COVID-19 is associated with dysregulated innate and adaptive immune responses. Brain. 2022.- Michael BD, et al. Para-infectious brain injury in COVID-19 persists at follow-up despite attenuated cytokine and autoantibody responses. Nat Commun. 2023.- Wook GK, et al. Post-hospitalisation COVID-19 cognitive deficits at one year are global and associated with elevated brain injury markers and grey matter volume reduction. Nat Med. 2024. Thank you for listening!Follow and share on X/Twitter: @NPodcasesCheck out the Neuro Podcases website: neuropodcases.co.uk #NeuroScienceResearch#Neuroscience#ClinicalNeuroscience#BrainHealth#Neurology#MedicalEducation#MedTwitter#BrainMatters#Brain#Nature
In this episode we are joined by Dr Ethan Meltzer to discuss how his approach to clinical reasoning in Neurology. Further information on his book can be found at the following link https://global.oup.com/academic/product/how-to-think-like-a-neurologist-9780197576663?cc=gb&lang=en&
In this episode we are joined by Professor Michael Jenkinson to discuss his career in Brain Tumour research
This is the first episode in our Neuroscience research series. In this episode we are joined by Professor Tony Mason to discuss his career in epilepsy research.
In this episode we are joined by Dr Mirasol Forcadela to discuss diagnosis and management of patients presenting with MS
In this episode we are joined by Dr Mirasol Forcadela to discuss Neuromyelitis Optica Spectrum Disorder
In this episode we are joined by Cognitive Neurologist Dr Christopher Kyndt to discuss his top tips for diagnostic assessment of patients presenting to cognitive clinic.
In this two part series on CNS infection we are joined by Dr Mark Ellul to discuss an approach to Meningitis and Encephalitis
In this episode we are joined by Consultant Neurologist and Neuro-opthalmologist Dr Sui Wong.
In this episode we are joined by Dr Regan Cooley to discuss his approach to a young patient presenting with ischaemic stroke.
In this episode we are joined by Senior Clinical Lecturer and Consultant Neurologist Dr James Lilleker to discuss how he approaches the patient presenting with a suspected myopathy
In this episode we are joined by Consultant vascular surgeon Mr Jagjeeth Naik to discuss the topic of carotid endarterectomy in secondary stroke prevention
In this episode we are joined by Professor Hannah Cock to discuss the topic of Status Epilepticus
In this episode we are joined by Consultant Neurologist Dr John Williamson to discuss some of the common referrals seen in general neurology clinic.
In this episode we are joined by Dr Stephen Keddie to discuss the topic of paraproteinaemic neuropathy
In this episode we are joined by Mr Carlton-Bland to discuss the diagnosis of cauda equine syndrome
In this episode we are joined by consultant anaesthetist Dr Jed Smith to discuss common clinical scenarios encountered on the Neuro ICU.
In this episode we are joined by Consultant Neurologist and Clinical Neurophysiologist Dr Edrich Rodrigues to discuss how nerve conduction studies
In this episode we are joined by Dr Gargi Banerjee to discuss the topic of cerebral amyloid angiopathy
In this episode we are joined by movement disorder specialist Dr Jayachandran Panicker to discuss his approach to myoclonus
In this episode we are joined by Dr Malcolm Steiger, consultant neurologist with special interest in movement disorders, to discuss management of Parkinson's disease.
In this episode we are joined by consultant neurologist and headache specialist Dr Nick Silver to discuss his approach to migraine
Building on from the principles discussed in part 1, in this second episode Dr John Williamson discusses localisation through clinical cases.
In this episode we are joined by consultant neurologist Dr Matt Jones to discuss his approach to a patient presenting with primary progressive aphasia
In this episode we are joined by consultant neuroradiologist Dr Shubhabrata Biswas to discuss the neuroradiological features of dementias. Please visit our website to access the video for this episode where you will also be able to view the images being discussed.
In this episode we are joined by Dr James Holt, consultant neurologist with a special interest in neuromuscular disorders, to discuss how he approaches a patient presenting with a suspected peripheral neuropathy.
In this episode we are joined by Dr Benedict Michael to discuss the neurological effects of Covid-19 infection. Alongside this we also discuss the practicalities of performing clinical research during an evolving global pandemic as well as some of the ongoing research he is currently conducting.
In this podcast episode we are joined by Dr Laura Bricio Moreno, a postdoc research fellow at the Massachusetts General Hospital in Harvard Medical School. The discussion focuses on the pathogenesis of HSV-1 encephalitis as well as some of the pre-clinical research currently being undertaken in this field.
In this episode we are joined by Dr Jeremy Mason to discuss the topic of hyperbaric oxygen therapy and its use in neurological disorders.
In this episode we are joined by consultant neuroligist Dr Rajith De Silva. The discussion focusses on his approach to a patient presenting with progressive cerebellar ataxia.
In this episode we are joined by consultant neurologist Dr Henry Zhao who is the operational clinical lead for the Melbourne mobile stroke unit. In the episode we discuss his experience working with the Melbourne mobile stroke unit alongside a more general discussion around the pre-hospital management stroke.
In this episode we are joined by consultant neurologist Dr Thomas Chemmanam to discuss his approach to disorders of the thalamus. During the episode we discuss the clinical importance of the thalamus and the myriad ways thalamic disorders may present in clinical practice.
In this episode we are joined by consultant neurologist Dr Regan Cooley to discuss his approach to the patient presenting with acute vertigo.
In this episode we are joined by consultant neurologist Dr Robert Edis to discuss motor neurone disease. In this second part of the episode we discuss the management of this condition.
Music: Good Starts - Jingle Punks https://youtu.be/NstTz8iyl-c
In this episode we are joined by consultant neurologist Dr Robert Edis to discuss motor neurone disease. In this first part of the episode we discuss the pathophysiology, clinical presentation and diagnostic approach to this condition.
Music: Good Starts - Jingle Punks https://youtu.be/NstTz8iyl-c
In this episode we are joined by Consultant neurologist and epilepsy specialist Professor Tony Marson to discuss current UK regulations regarding epilepsy and driving.
In this episode we are joined by Dr Anu Jacob to discuss his approach to patients presenting with a suspected spinal cord disorder. Using two cases we discuss how the clinical examinations can localise the site of pathology to the spinal cord and discuss the different clinical features of common spinal cord syndromes.
Music: Good Starts - Jingle Punks https://youtu.be/NstTz8iyl-c
In this episode we are joined by Associate Professor Nawaf Yassi to discuss his approach to the investigation and management of a patient presenting with intracerebral haemorrhage. We discuss boht common and rarer causes for the presentation alongside the evidence base behind treatment decisions.
Music: Good Starts - Jingle Punks https://youtu.be/NstTz8iyl-c
In this episode we are joined by cognitive neurologist Dr Rhys Davies to discuss his approach to cognitive examination.
In this episode with Dr Mills, Consultant Neuroradiologist, we discuss acute imaging taken in the AED from a patient presenting with a thunderclap headache. See the Neuropodcases website for the accompanying video - www.neuropodcases.co.uk
In this episode we are joined by Professor Bruce Campbell to discuss CT perfusion scanning and it's role in the diagnosis and management of acute ischaemic stroke. Visit www.neuropodcases.co.uk to access the radiology images discussed in the episode.
All clinical cases in these podcast episodes have been created based on past interactions with real patients but are not intended to represent any specific person. No specific individual patient information will ever be provided in the podcast.
Music: Good Starts - Jingle Punks https://youtu.be/NstTz8iyl-c
In this episode we are joined by Dr Michael Bonello who discusses his approach to a patient with movement disorders.
Music: Good Starts - Jingle Punks https://youtu.be/NstTz8iyl-c
In this episode we are joined by Professor Bernard Yan to discuss the past, present and future of mechanical thrombectomy as a treatment for patients presenting with acute ischaemic stroke.
Music: Good Starts - Jingle Punks https://youtu.be/NstTz8iyl-c
Diagnosis of an acute stroke is only the first step in the management of a patient. In this episode we discuss how to approach investigate for stroke aetiology as well as manage future stroke prevention.
Music: Good Starts - Jingle Punks https://youtu.be/NstTz8iyl-c
We discuss four cases of transient loss of consciousness that might get referred to the first fit clinic from GP or AED.
Dr Smith highlights important features that help make a diagnosis and also discusses a very important presentation to be aware of!
\Music: Good Starts - Jingle Punks https://youtu.be/NstTz8iyl-c
A chat through 4 cases that may present to a cognitive clinic with consultant Neurologist, Dr Davies.
In this podcast, we discuss three major causes of dementia and how they present, along with a fourth, common presentation.
Music: Good Starts - Jingle Punks https://youtu.be/NstTz8iyl-c
A session with Dr Smith, consultant Neurologist, about how to take a neurologically focussed history based on answering 3 key questions.
In this podcast, we also discuss cases to demonstrate how important a clear history is when looking at a neurological presentation.
Music: Good Starts - Jingle Punks https://youtu.be/NstTz8iyl-c
Discussion with consultant Neurosurgeon, Mr Carleton-Bland, about back pain - what symptoms and signs to worry about and when to act on them.
This discussion covers the more benign causes of back pain along with the 'not to miss' cauda equina and metastatic cord compression that are often seen in GP and emergency departments.
All clinical cases in these podcast episodes have been created based on past interactions with real patients but are not intended to represent any specific person. No specific individual patient information will ever be provided in the podcast.
The information in this episode is intended for the purposes of medical student education and should not be used as medical advice for your own medical treatment or the treatment of your patients.
This episode with consultant Neurologist, Dr Davies, provides a memorable approach to aid the diagnosis of a confused patient on a ward.
All clinical cases in these podcast episodes have been created based on past interactions with real patients but are not intended to represent any specific person. No specific individual patient information will ever be provided in the podcast.
The information in this episode is intended for the purposes of medical student education and should not be used as medical advice for your own medical treatment or the treatment of your patients.
In this episode, Dr Davies, consultant Neurologist, discusses his subspecialty interest of cognitive neurology - what conditions he helps manage and how the roles of psychology and psychiatry play a crucial role in managing patients.
All clinical cases in these podcast episodes have been created based on past interactions with real patients but are not intended to represent any specific person. No specific individual patient information will ever be provided in the podcast.
The information in this episode is intended for the purposes of medical student education and should not be used as medical advice for your own medical treatment or the treatment of your patients.
Discussion with consultant Neurologist, Dr Davies, regarding the anatomy and clinical findings of a foot drop with common and important causes reviewed.
All clinical cases in these podcast episodes have been created based on past interactions with real patients but are not intended to represent any specific person. No specific individual patient information will ever be provided in the podcast.
The information in this episode is intended for the purposes of medical student education and should not be used as medical advice for your own medical treatment or the treatment of your patients.
A discussion with neuromuscular specialist, Dr Dougan, regarding a case of sensory and motor disturbance that progresses over months: what to consider, how to investigate and key points when considering nerve conduction studies.
All clinical cases in these podcast episodes have been created based on past interactions with real patients but are not intended to represent any specific person. No specific individual patient information will ever be provided in the podcast.
The information in this episode is intended for the purposes of medical student education and should not be used as medical advice for your own medical treatment or the treatment of your patients.
A discussion with Dr Samantha Mills, Consultant Neuroradiologist, about considerations when assessing a mass lesion on brain imaging.
In this episode we discuss the diagnostic approach to a patient presenting with suspected stroke with Dr Regan Cooley.
All clinical cases in these podcast episodes have been created based on past interactions with real patients but are not intended to represent any specific person. No specific individual patient information will ever be provided in the podcast.
The information in this episode is intended for the purposes of medical student education and should not be used as medical advice for your own medical treatment or the treatment of your patients.
In this episode we discuss the diagnostic approach to a patient presenting with a suspected stroke with Dr Regan Cooley.
All clinical cases in these podcast episodes have been created based on past interactions with real patients but are not intended to represent any specific person. No specific individual patient information will ever be provided in the podcast.
The information in this episode is intended for the purposes of medical student education and should not be used as medical advice for your own medical treatment or the treatment of your patients.
A discussion with Dr Rhys Davies regarding two different presentations that have a common pathology.
All clinical cases in these podcast episodes have been created based on past interactions with real patients but are not intended to represent any specific person. No specific individual patient information will ever be provided in the podcast.
The information in this episode is intended for the purposes of medical student education and should not be used as medical advice for your own medical treatment or the treatment of your patients.
A discussion with movement disorder specialist, Dr Richard Ellis, about an approach to assessment and management of a patient with a tremor.
All clinical cases in these podcast episodes have been created based on past interactions with real patients but are not intended to represent any specific person. No specific individual patient information will ever be provided in the podcast.
The information in this episode is intended for the purposes of medical student education and should not be used as medical advice for your own medical treatment or the treatment of your patients.
A discussion with consultant neurosurgeon, Mr Carleton-Bland, about an approach to history taking from a neurosurgical perspective with an illustrative case and interpretation of a scan.
All clinical cases in these podcast episodes have been created based on past interactions with real patients but are not intended to represent any specific person. No specific individual patient information will ever be provided in the podcast.
The information in this episode is intended for the purposes of medical student education and should not be used as medical advice for your own medical treatment or the treatment of your patients.
This episode discusses presentations to the TIA clinic with stroke neurologist Dr Regan Cooley.
All clinical cases in these podcast episodes have been created based on past interactions with real patients but are not intended to represent any specific person. No specific individual patient information will ever be provided in the podcast.
The information in this episode is intended for the purposes of medical student education and should not be used as medical advice for your own medical treatment or the treatment of your patients.
A discussion with Dr Bonello regarding key points to consider in genetic conditions, with a focus on the inheritance, clincial features and management options in Huntington's Disease.
All clinical cases in these podcast episodes have been created based on past interactions with real patients but are not intended to represent any specific person. No specific individual patient information will ever be provided in the podcast.
The information in this episode is intended for the purposes of medical student education and should not be used as medical advice for your own medical treatment or the treatment of your patients.
Discussion with Dr Davies about the key points and common difficulties in taking a neurology focussed history.
All clinical cases in these podcast episodes have been created based on past interactions with real patients but are not intended to represent any specific person. No specific individual patient information will ever be provided in the podcast.
The information in this episode is intended for the purposes of medical student education and should not be used as medical advice for your own medical treatment or the treatment of your patients.
A case based discussion with consultant neurologist Dr Rhys Davies.
All clinical cases in these podcast episodes have been created based on past interactions with real patients but are not intended to represent any specific person. No specific individual patient information will ever be provided in the podcast.
The information in this episode is intended for the purposes of medical student education and should not be used as medical advice for your own medical treatment or the treatment of your patients.
Discussion with Dr Smith regarding his approach to epilepsy definition, diagnosis and classification.
All clinical cases and "patients" presented in this podcast are fictional. They are made up based on past interactions with real patients but are not intended to represent any specific person. No specific individual patient information will ever be provided in the podcast. Any direct similarities to any real person is purely coincidental and unintentional.
The information in this episode is intended for the purposes of medical student education and should not be used as medical advice. By listening to this material, you agree not to use it as the basis for your own medical treatment or the treatment of your patients.
In this bonus podcast episode we focus on the clinico-anatomical correlation of neurological symptoms.
All clinical cases in these podcast episodes have been created based on past interactions with real patients but are not intended to represent any specific person. No specific individual patient information will ever be provided in the podcast.
The information in this episode is intended for the purposes of medical student education and should not be used as medical advice for your own medical treatment or the treatment of your patients.
In thispodcast episode we focus on the clinico-anatomical correlation of neurological symptoms.
All clinical cases in these podcast episodes have been created based on past interactions with real patients but are not intended to represent any specific person. No specific individual patient information will ever be provided in the podcast.
The information in this episode is intended for the purposes of medical student education and should not be used as medical advice for your own medical treatment or the treatment of your patients.
In this bonus podcast episode we focus on the clinico-anatomical correlation of neurological symptoms.
All clinical cases in these podcast episodes have been created based on past interactions with real patients but are not intended to represent any specific person. No specific individual patient information will ever be provided in the podcast.
The information in this episode is intended for the purposes of medical student education and should not be used as medical advice for your own medical treatment or the treatment of your patients.
In this bonus podcast episode we focus on the clinico-anatomical correlation of neurological symptoms.
All clinical cases in these podcast episodes have been created based on past interactions with real patients but are not intended to represent any specific person. No specific individual patient information will ever be provided in the podcast.
The information in this episode is intended for the purposes of medical student education and should not be used as medical advice for your own medical treatment or the treatment of your patients.
In this podcast episode we discuss a presentation of walking difficulties.
All clinical cases in these podcast episodes have been created based on past interactions with real patients but are not intended to represent any specific person. No specific individual patient information will ever be provided in the podcast.
The information in this episode is intended for the purposes of medical student education and should not be used as medical advice for your own medical treatment or the treatment of your patients.
In this podcast episode we discuss a presentation of acute confusion.
All clinical cases in these podcast episodes have been created based on past interactions with real patients but are not intended to represent any specific person. No specific individual patient information will ever be provided in the podcast.
The information in this episode is intended for the purposes of medical student education and should not be used as medical advice for your own medical treatment or the treatment of your patients.
In this episode we discuss a presentation of episodic headache.
All clinical cases in these podcast episodes have been created based on past interactions with real patients but are not intended to represent any specific person. No specific individual patient information will ever be provided in the podcast.
The information in this episode is intended for the purposes of medical student education and should not be used as medical advice for your own medical treatment or the treatment of your patients.
In this podcast episode we discuss a presentation of transient loss of consciousness.
All clinical cases in these podcast episodes have been created based on past interactions with real patients but are not intended to represent any specific person. No specific individual patient information will ever be provided in the podcast.
The information in this episode is intended for the purposes of medical student education and should not be used as medical advice for your own medical treatment or the treatment of your patients.
In this podcast episode we discuss a presentation of acute headache.
All clinical cases in these podcast episodes have been created based on past interactions with real patients but are not intended to represent any specific person. No specific individual patient information will ever be provided in the podcast.
The information in this episode is intended for the purposes of medical student education and should not be used as medical advice for your own medical treatment or the treatment of your patients.