Dov is once again joined by Dr. Brian Cornblatt, Chief Medical Officer at BioHarvest Sciences, for a spirited and in-depth conversation. They take a deep dive into the detox process and discuss the science behind VINIA, a revolutionary supplement that leverages the power of technology to deliver unparalleled bioavailability of detoxifying phytochemical compounds. Dr. Cornblatt is a Johns Hopkins University School of Medicine Graduate with a Ph.D. in Pharmacology and Molecular Sciences and a postdoctoral fellowship from the Johns Hopkins Bloomberg School of Public Health, Environmental Health Sciences Division of Toxicology. He is also the inventor of three issued patents and four pending provisional patents focused on plant-based bioactive compounds and health promotion.

RESOURCES

Check out the following videos and studies to learn more about VINIA:

The Science of VINIA

VINIA’s Solubility Advantage

VINIA’s Bioavailability Advantage

Research Article

For a helpful primer on the phases of detoxification, be sure to listen to the previous episode, Detox Decoded.

Got a question, comment or suggestion for a future show topic? Email ROTC@rootofthecause.net.

SHOW NOTES

  • 5:15 – Dr. Cornblatt explains why he likes discussing the chemical compounds heterocyclic amines and benzene
  • 9:05 – Testing for benzene levels in the body
  • 10:30 – Objective methods Dr. Cornblatt implements to determine one’s ability to detox benzene using phytochemicals; Lab report measuring benzene levels (see page 4).
  • 11:34 – Phase 2 enzymes and how they work like a dimmer switch; how plant-based bioactive compounds can modulate the dimmer switch
  • 17:27 – Glutathione S Transferase: how these enzymes work and the many redundancies at the cellular level
  • 19:30 – How Glutathione is made and how plant phytochemicals can upregulate it
  • 21:40 – Are plant phytonutrients antioxidants, pro-oxidants or “indirect” antioxidants?
  • 24:14 – The evolutionary principle behind how and why these plant compounds produce phytochemicals and how we benefit from them
  • 26:32 – The most-known benefits of taking phytochemicals; the stimulation of NRF2, ET1 (impacts vasoconstriction) and eNOS (impacts vasodilation); how VINIA stimulates all 3 pathways, helping to modulate blood pressure and oxygenate the blood, aiding in the reversal of chronic fatigue
  • 31:40 – How the resveratrol (piceid form) in the product VINIA is vastly different from your standard resveratrol (cis and trans form) formulas; unparalleled absorbability and bioavailability and the innovative ways Dr. Cornblatt’s team at BioHarvest Sciences is able to achieve this
  • 41:00 – New innovations that are coming soon from BioHarvest Sciences
  • 44:00 – VINIA’s impact on insulin sensitivity/blood sugar stability; VINIA's wide-ranging polyphenolic content versus standard resveratrol's limited polyphenolic content (how resveratrol is like a lone drum while VINIA is the entire orchestra).
  • 48:55 – LDL cholesterol versus oxidized LDL and how VINIA upregulates a phase 2 enzyme called PON1, which helps to prevent the oxidation of LDL cholesterol, thus playing a profoundly cardio-protective role
  • 59:37 – The value of genetic testing when applying nutraceuticals and pharmaceuticals in a customized way
  • 1:04 – With NRF2 activation, does the body recognize the difference between human-made chemicals from plant-derived phytochemicals? Can we over-stimulate NRF2 with phytochemicals if it’s chronically being stimulated by human-made chemicals that are ubiquitous?
  • 1:11 – Is there merit to taking multiple supplemental phytochemicals if any one phytochemical in isolation has been shown to upregulate NRF2?

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