Jim Goetz and Dr. Mike Brandon of Functionised discuss the in's and out's of body fat, why you gain it, whats good about it, what's bad about it and how to remove excess.

Woes of Fat

Define fat- adipose, so body fat%, not bmi!

Speaking white adipose here, not brown

For men, a percentage of body fat greater than 25% defines obesity, with 21-25% being borderline. For women, over 33% defines obesity, with 31-33% being borderline.

-other than being ugly, we get told to lose it, but why?

Just to buy new clothes

Physical

Excess weight on joints, back, neck

More difficult for correct posture which leads to more pain

Hormones it effects- why they matter

Leptin

suppress hunger, when depleted increases obesity- Where does it come from/why does it stop

Injections dont help. Ceiling for it and brain becomes resistant to it Does not increase leptin by decreasing food intake; rather, lack of leptin acts as a signal to increase food intake Obesity decreases sensitivity to it, so DM and obese have a harder time feeling full

Aromatase- is released

Converts test to estrogen- decreases metabolism, increases insulin resistance

High estrogen issues

Females- Homronal acne, depressed metabolism,irregular menstration, bloating, cold/itchy hands/feet, insomnia, headaches, low sex drive, increased breast and other cancer risks

Males- gynecamastia, low sex drive, Erectile dsfunction, infertilaty

Resistin- also released by epithelial cells, increased secretion with a high body fat percentage

Directly increases insulin resistance-

Increases production of LDL cholesterol

Increases cardio vascular disease risk

Appears that centralised/wastline adipose releases more than other locations

Association with DMtype 2 and centralised obesity faster than booty fat

Pro inflammatides- mainly from resistin

Interlukin 1, 3, 6; tumor necrosis factor-

Causes systemic long term inflammation, like food sensitivities too

Inflammation basis for …

Increases risk of rheumatoid conditions

Neuro transmitters

Serotonin is released with insulin secretion, mainly from carb diet which is VERY common in obesity.

“Use too much” serotonin and we get a little depressed, eat more sugar to increase mood, becomes less effective so do more frequently

Part of the addiction cycle of carby foods

Leads to many more poor choices when depressed

Serotonin and dopamine

Decreased transporters, so it gets harder to use these happy hormones/endorphions

Comorbidities- things that are increased risk and caused by or in part by obesity

Heart disease

DM- resistin, and poor life style habits

Cancer- hormonal cancers more so, but increased of all cancers since others are inflammatory

Stroke - better chance surviving it...but also getting it

Homron imbalances- stated above

GI issues - inflammation of bowel, and then colon cancer,

Dementia-

Healing time?

Depression- serotonin burn out

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