Found My Fitness - Rhonda Patrick
Podcast Notes Key Takeaways * The way we respond to a diet is highly individualized – people uniquely respond to diet, even if fed the exact same foods * “The dominant factor that determines the diurnal activity of microbes throughout the day is the timing of our feeding.” – Dr. Eran Elinav * Our gut microbiome senses when we eat or don’t eat and changes activity accordingly * Changes in health status, stress status, medication, the way we live, where we live, etc. reflect on our gut microbes and may impact the risk of developing diseases * A leaky gut is related to disease: diverse molecules secreted by the gut microbe are important in creating the normal state of leakiness which allows us to absorb food and block foreign molecules we don’t want in our body – when disrupted, there’s a strong link to disease (cancer, autoimmune & cardiovascular disease) * The success of probiotic supplementation depends on whether the exogenous probiotic is welcomed by endogenous microbes in the gut * The complexity of taking antibiotics and probiotics: giving probiotics together with antibiotics may protect individuals from adverse effects of antibiotics – but the price may be a chronic disturbance in gut microbiome with probiotics taking over and reducing the diversity of the innate gut microbiome * About 80% of overweight people who diet will gain back the weight plus some – the microbiome seems to store a metabolic memory of past obesity which predisposes people to exaggerated weight gain * Best practices for a healthy microbiome: (1) maintain a consistent, healthy sleep pattern; (2) stop smoking cigarettes; (3) eat during a regular window during the day (avoid night eating); (4) explore wearing a continuous glucose monitor for personalized data; (5) try a personalized nutrition approach (check out Day Two)
Read the full notes @ podcastnotes.org
Eran Elinav, MD, PhD, is a professor of immunology and principal investigator at the Weizmann Institute of Science in Tel Aviv, Israel, where he co-directs the Personalized Nutrition Project. Dr. Elinav is also a principal investigator at the German Cancer Research Center in Heidelberg, Germany. His research focuses on understanding the complex interactions between humans and the bacteria that reside in their gut and how these interactions shape human health and disease.
In this episode, Dr. Elinav and I discuss...
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